Protein (view, download) , Domain (view, download)
PLK4_Hsap_SAK                 MATC--------------------------------------------------------
PLK3_Hsap_PLK2                MEPAAGF-----------------L--S-P------------------------------
PLK2_Hsap_PLK2                MELLRTI-----------------T--YQPA-AST------K------------------
PLK1_Hsap_PLK1                MSAAVTA-----------------G--K-L------------------------------
polo_Dmel_PLK1                MAAKPED-----------------K-----------------------------------
SAK_Dmel_SAK                  MLSNRA------------------------------------------------------
PLK5_Mmus_PLK2                MEPRSRR-----------------------------------------------------
PLK4_Mmus_SAK                 MAAC--------------------------------------------------------
PLK3_Mmus_PLK2                MEPAAGF-----------------L--S-P------------------------------
PLK2_Mmus_PLK2                MELLRTI-----------------T--YQPA-AGT------K------------------
PLK1_Mmus_PLK1                MNAAAKA-----------------G--K-L------------------------------
plk-2_Cele_PLK1               MQRVQPS-----------------A-----------------------------------
plk-1_Cele_PLK1               MNRLPNI-----------------A--K-P------------------------------
F55G1.8_Cele_PLK1             MQHVLRT-----------------R-----------------------------------
CDC5_Scer_PLK1                MSLGPLK-----------------AIND------------------------KQLNTRSK
zyg-1_Cele_SAK                MSGGKSG-----------------------------------------------------
PLK_Ddis_PLK1                 MVSINQN-----------------F--KLPI-SMNSQ-------PIQ--IQQQQFK----
8635_Tthe_SAK                 MQGLA-------------------------------------------------------
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   MSYFKNI-----------------F--KLRLRDFDKEGVVVFLVEVQLTVENKQFM----
21183_Tthe_SAK                MIQQK-------------------------------------------------------
22503_Tthe_PLK-Unclassified   MSTEN-------------------------------------------------------
5034_Tthe_SAK                 MFSQE-------------------------------------------------------
8829_Tthe_PLK-Unclassified    MDKAN-------------------------------------------------------
SAK_Spur_SAK                  ME----------------------------------------------------------
PLK1_Spur_PLK1                MASRHKE-----------------D-----------------------------------
PLK2_Spur_PLK2                MPLTRSPVLPVGLSKDVRYTMDQLQ--K-P------------------------------
n1170_Tthe_PLK-Unclassified   MSNQD-------------------------------------------------------
n808_Tthe_PLK-Unclassified    MSNQD-------------------------------------------------------
CC1G_07437_Ccin_PLK1          MYQMNGY-----------------R--M-P------------------------------
AqueK200_Aque_PLK1            MAHHLSE-----------------K--D-K------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   MSHSNAP-----------------------------------------------------


PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                ---------------------RP-------------------------------------
PLK2_Hsap_PLK2                MCE------------------QA-----------LGKGCGA-------------------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                ---------------------RP-------------------------------------
PLK2_Mmus_PLK2                MCE------------------QA-----------LGKACGG-------------------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                LVHTPIKGNTADLVGKENHFKQTKRLDPNND-----------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 -QP------------------QQ-------QPQQKSNSCFSDQENYPANIQPSSSTSSSS
8635_Tthe_SAK                 ------------------------------Q-----------------------------
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   -SQ------------------QA-------A-----------------------------
21183_Tthe_SAK                ------------------------------K-----------------------------
22503_Tthe_PLK-Unclassified   ------------------------------Q-----------------------------
5034_Tthe_SAK                 ------------------------------E-----------------------------
8829_Tthe_PLK-Unclassified    ------------------------------E-----------------------------
SAK_Spur_SAK                  ------------------------------------------------------------
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   ------------------------------K-----------------------------
n808_Tthe_PLK-Unclassified    ------------------------------K-----------------------------
CC1G_07437_Ccin_PLK1          ------------------------------------------------------------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                ---------------------F----------------------------------QRA-
PLK2_Hsap_PLK2                ---------------------D----------------------------------SKK-
PLK1_Hsap_PLK1                ----------------------------------------------------------A-
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                ---------------------F----------------------------------PRA-
PLK2_Mmus_PLK2                ---------------------D----------------------------------SKK-
PLK1_Mmus_PLK1                ----------------------------------------------------------A-
plk-2_Cele_PLK1               ----------------------------------------------------------A-
plk-1_Cele_PLK1               ----------------------------------------------------------P-
F55G1.8_Cele_PLK1             ----------------------------------------------------------G-
CDC5_Scer_PLK1                --------------------------------------------------------HHH-
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 SSSIHITKSMVIRPPLESNQPQPQQQQQQQQTLQQIHHQQVQLQQQQSLQMQQQQLQQQ-
8635_Tthe_SAK                 --------------------------------------------------------TPFD
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   --------------------------------------------------------QQQ-
21183_Tthe_SAK                --------------------------------------------------------DQK-
22503_Tthe_PLK-Unclassified   --------------------------------------------------------NQQ-
5034_Tthe_SAK                 --------------------------------------------------------AKE-
8829_Tthe_PLK-Unclassified    --------------------------------------------------------GKD-
SAK_Spur_SAK                  ------------------------------------------------------------
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ----------------------------------------------------------A-
n1170_Tthe_PLK-Unclassified   --------------------------------------------------------QQQ-
n808_Tthe_PLK-Unclassified    --------------------------------------------------------QQQ-
CC1G_07437_Ccin_PLK1          ----------------------------------------------------------P-
AqueK200_Aque_PLK1            ----------------------------------------------------------L-
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                ---A--AAPAPPA-------------------GPGP------------------------
PLK2_Hsap_PLK2                ---K--RPPQPPE-------------------ESQP------------------------
PLK1_Hsap_PLK1                ---R--APADPGK-------------------AGVP------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                ---A--APSAPPA-------------------GPGP------------------------
PLK2_Mmus_PLK2                ---K--RPQQPSE-------------------DGQP------------------------
PLK1_Mmus_PLK1                ---R--APADLGK-------------------GGVP------------------------
plk-2_Cele_PLK1               ---R--VKSQ--------------------------------------------------
plk-1_Cele_PLK1               ---Q--KSNQ--------------------------------------------------
F55G1.8_Cele_PLK1             ---N--SAQDKNK-----------------------------------------------
CDC5_Scer_PLK1                ---Q--PAQKKKR-----------------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ---Q--QQ-QQQQ-------------------QMPP------------------------
8635_Tthe_SAK                 LFEPQQRLFRLPQ-------------------KKSGVLKQQIFKEFIEKAQIKIKILDEE
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   ---P--QQ-KQSE-------------------QGQN------------------------
21183_Tthe_SAK                ---P--KSSS--Q-------------------Q---------------------------
22503_Tthe_PLK-Unclassified   ---Q--KPAQDPV-------------------SCY-------------------------
5034_Tthe_SAK                 ---Q--NSDEQNQ-------------------E---------------------------
8829_Tthe_PLK-Unclassified    ---Q--------------------------------------------------------
SAK_Spur_SAK                  ------------------------------------------------------------
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ---P-LSPEDTPKTTPS---LSSKPHGAGREENVKP------------------------
n1170_Tthe_PLK-Unclassified   ---Q--QQ-QQPQ-------------------GAQR------------------------
n808_Tthe_PLK-Unclassified    ---Q--QQ-QQPQ-------------------GAQR------------------------
CC1G_07437_Ccin_PLK1          ---A--APGPSSKRNPLVNAVNHHPNV--MQMNAVP------------------------
AqueK200_Aque_PLK1            ---G--S-----------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                ------------------------------------------------------------
PLK2_Hsap_PLK2                ------------------------------------------------------------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                ------------------------------------------------------------
PLK2_Mmus_PLK2                ------------------------------------------------------------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                ------------------------------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ------------------------------------------------------------
8635_Tthe_SAK                 NDNEVLFYTPILFGYLSLIILKESSSTIILKHTLCYCNGKPYLIKDHQIRLLFTRCLNKI
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   ------------------------------------------------------------
21183_Tthe_SAK                ------------------------------------------------------------
22503_Tthe_PLK-Unclassified   ------------------------------------------------------------
5034_Tthe_SAK                 ------------------------------------------------------------
8829_Tthe_PLK-Unclassified    ------------------------------------------------------------
SAK_Spur_SAK                  ------------------------------------------------------------
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   ------------------------------------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ------------------------------------------------------------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                ------------P--P--------------------------------------------
PLK2_Hsap_PLK2                ------------P--Q--------------------------------------------
PLK1_Hsap_PLK1                ---------------G--------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                ------------P--A--------------------------------------------
PLK2_Mmus_PLK2                ---------------Q--------------------------------------------
PLK1_Mmus_PLK1                ---------------G--------------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                ------------------------------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ------------P--QS-------------------------------------------
8635_Tthe_SAK                 NNIEKFSKYAMNP--RNGEISLKDALFFEKETFQKFNESPLLAIKPMLELYNQQIHILKQ
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   ------------N--NN-------------------------------------------
21183_Tthe_SAK                ------------------------------------------------------------
22503_Tthe_PLK-Unclassified   ------------------------------------------------------------
5034_Tthe_SAK                 ------------------------------------------------------------
8829_Tthe_PLK-Unclassified    ------------------------------------------------------------
SAK_Spur_SAK                  ------------------------------------------------------------
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------PIPP--------------------------------------------
n1170_Tthe_PLK-Unclassified   ------------------------------------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ------------PVPA--------------------------------------------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                -----------SA----LR-----------------------------------------
PLK2_Hsap_PLK2                -----------SQ-AQVPP-----------------------------------------
PLK1_Hsap_PLK1                -----------VA----AP-----------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                -----------NA----SP-----------------------------------------
PLK2_Mmus_PLK2                --------------AQVTP-----------------------------------------
PLK1_Mmus_PLK1                -----------DA----VP-----------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                ------------------------------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 -----------LP----NK-----------------------------------------
8635_Tthe_SAK                 YTKLILVVLEELP----QIFNQYSDISFLSLNQINLQLLKVKMWLIDPDTFEDQSEINEQ
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   -----------DQ----GV-----------------------------------------
21183_Tthe_SAK                ------------------------------------------------------------
22503_Tthe_PLK-Unclassified   ------------------------------------------------------------
5034_Tthe_SAK                 ------------------------------------------------------------
8829_Tthe_PLK-Unclassified    ------------------------------------------------------------
SAK_Spur_SAK                  ------------------------------------------------------------
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                -----------AR----AP-----------------------------------------
n1170_Tthe_PLK-Unclassified   ------------------------------------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          -----------KAPAKG-P-----------------------------------------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 ------------------------I-G-EKIEDFKVGNLLGKGSFAGVYR----------
PLK3_Hsap_PLK2                -G-PE-LEMLAG-LPTSDP-GRLIT-DPRSGRTYLKGRLLGKGGFARCYE----------
PLK2_Hsap_PLK2                -AAPH-HHHHH-SHSGPEI-SRIIV-DPTTGKRYCRGKVLGKGGFAKCYE----------
PLK1_Hsap_PLK1                -GAP-----AA-APPAKEI-PEVLV-DPRSRRRYVRGRFLGKGGFAKCFE----------
polo_Dmel_PLK1                ---------------STDI-PDRLV-DINQRKTYKRMRFFGKGGFAKCYE----------
SAK_Dmel_SAK                  ------------------------F-G-ETIEDYEVQHLLGKGGFATVYK----------
PLK5_Mmus_PLK2                ------------RRSRQLV-ATFLR-DPGSGRVYRRGKLIGKGAFSRCYK----------
PLK4_Mmus_SAK                 ------------------------I-G-ERIEDFKVGNLLGKGSFAGVYR----------
PLK3_Mmus_PLK2                -R-SE-PEVLAGPRAPDPP-GRLIT-DPLSGRTYTKGRLLGKGGFARCYE----------
PLK2_Mmus_PLK2                -AAPH-HHHHH-SHSGPEI-SRIIV-DPTTGKRYCRGKVLGKGGFAKCYE----------
PLK1_Mmus_PLK1                -GAP-----VA-APLAKEI-PEVLV-DPRSRRQYVRGRFLGKGGFAKCFE----------
plk-2_Cele_PLK1               ---------KK-EKAPPDV-PDVIL-DGERKTRYEKGKFLGKGGFAHCYE----------
plk-1_Cele_PLK1               ---------RK-EKAPPEV-PALIA-DKDRGTYYEKGRFLGKGGFAHCYE----------
F55G1.8_Cele_PLK1             ------------KH-VPNV-PPIIY-D-DMQVPYEKGAFLGEGGFAHCFE----------
CDC5_Scer_PLK1                ----E----KL-SA-LCKT-PPSLI-K-TRGKDYHRGHFLGEGGFARCFQ----------
zyg-1_Cele_SAK                ----------------------------SRLSAYSHLKEIGKGGFGVVYA----------
PLK_Ddis_PLK1                 -SNEP----QE-PIVVYET-IR-SG-DSKRLKEYRQGEFLGKGGFAKCYL----------
8635_Tthe_SAK                 IKRQS----Q--I-VQKKDDLKILNE-IEIIGDIQNIEQINKGGFGSIQKGKLAKILKYP
18358b_Tthe_PLK-Unclassified  -----------------------------------------KGGFAKCYE----------
18380_Tthe_PLK-Unclassified   -ANYP----TE-QKIIEEKTENKVT-GEKIIKKYSRGKLLGSGGFAKCYE----------
21183_Tthe_SAK                --------------V-EEEENHLMNSISTSLHNFKITLTLGRGAGSCVFL----------
22503_Tthe_PLK-Unclassified   -QAQP----QR-N-LLHEKRKN-QDGEWKVERSYEVLSKLGKGGFAKVYL----------
5034_Tthe_SAK                 --------------INEQERNSLFNSLSAQLSDYIISHPIGSGAGSLVVK----------
8829_Tthe_PLK-Unclassified    ------------LIIIEEK-ISKVN-GEMAVKKYLRGKLLGKGGFAKCYE----------
SAK_Spur_SAK                  ----------------------------DRIENYQVLNLLGRGGFACVYR----------
PLK1_Spur_PLK1                -------------LRVKEV-PDVVT-DPSTGKTYTKGRFLGKGGFAKCYE----------
PLK2_Spur_PLK2                -KAT-----PA-VSKLPEL-PAVIV-DPESGERYRRGRLLG-GGFARCYE----------
n1170_Tthe_PLK-Unclassified   -AASD----TE-PLIIEER-VQIVN-GEQIIKRYQRGSLLGKGGFAKCFQ----------
n808_Tthe_PLK-Unclassified    -AASD----TE-PLIIEER-VQIVN-GEQIIKRYQRGSLLGKGGFAKCFQ----------
CC1G_07437_Ccin_PLK1          -SSPPLPRQNS-KTRPPSP-PKVIS-DKAGRLQFNRVGFLGEGGFARVYE----------
AqueK200_Aque_PLK1            ----------A-SSLSKPL-KEFVT-NPDTKKRYEKGRFLGKGGFAKCYE----------
AqueK201_Aque_SAK             --------------------------------DYEVLNRLGKGSFADVYR----------
GK066_Glam_PLK-Unclassified   -----------------EL-HPQIV-DPFHNVTYRPGKLLGKGGFAYVYE----------
                                                                        *. .

PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                ------------------------------------------------------------
PLK2_Hsap_PLK2                ------------------------------------------------------------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                ------------------------------------------------------------
PLK2_Mmus_PLK2                ------------------------------------------------------------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                ------------------------------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ------------------------------------------------------------
8635_Tthe_SAK                 LYGHFSQTMSLITKLYIMWQIAQGIQFLTSKNVAHLDLKPANIVISKGYLAKIIDFGEAY
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   ------------------------------------------------------------
21183_Tthe_SAK                ------------------------------------------------------------
22503_Tthe_PLK-Unclassified   ------------------------------------------------------------
5034_Tthe_SAK                 ------------------------------------------------------------
8829_Tthe_PLK-Unclassified    ------------------------------------------------------------
SAK_Spur_SAK                  ------------------------------------------------------------
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   ------------------------------------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ------------------------------------------------------------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                ------------------------------------------------------------
PLK2_Hsap_PLK2                ------------------------------------------------------------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                ------------------------------------------------------------
PLK2_Mmus_PLK2                ------------------------------------------------------------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                ------------------------------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ------------------------------------------------------------
8635_Tthe_SAK                 HPDVCNGKEFYNNQQRLIFKSYFLMKGNPNYKPGRTLPYTPYSNNNDRQASYKNLDIFSF
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   ------------------------------------------------------------
21183_Tthe_SAK                ------------------------------------------------------------
22503_Tthe_PLK-Unclassified   ------------------------------------------------------------
5034_Tthe_SAK                 ------------------------------------------------------------
8829_Tthe_PLK-Unclassified    ------------------------------------------------------------
SAK_Spur_SAK                  ------------------------------------------------------------
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   ------------------------------------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ------------------------------------------------------------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                ------------------------------------------------------------
PLK2_Hsap_PLK2                ------------------------------------------------------------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                ------------------------------------------------------------
PLK2_Mmus_PLK2                ------------------------------------------------------------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                ------------------------------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ------------------------------------------------------------
8635_Tthe_SAK                 GMVLSEIVFDTYPVDFKRGALHKLEEKFSRGDIRGRLVKNYQRHFGPKHIINLLHCLIFR
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   ------------------------------------------------------------
21183_Tthe_SAK                ------------------------------------------------------------
22503_Tthe_PLK-Unclassified   ------------------------------------------------------------
5034_Tthe_SAK                 ------------------------------------------------------------
8829_Tthe_PLK-Unclassified    ------------------------------------------------------------
SAK_Spur_SAK                  ------------------------------------------------------------
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   ------------------------------------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ------------------------------------------------------------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                ------------------------------------------------------------
PLK2_Hsap_PLK2                ------------------------------------------------------------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                ------------------------------------------------------------
PLK2_Mmus_PLK2                ------------------------------------------------------------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                ------------------------------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ------------------------------------------------------------
8635_Tthe_SAK                 CIDEKENRPTIDWIILISIYFKEVNKFYQQQICKHKKTFKATKRVLTKKESTEIYFERQI
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   ------------------------------------------------------------
21183_Tthe_SAK                ------------------------------------------------------------
22503_Tthe_PLK-Unclassified   ------------------------------------------------------------
5034_Tthe_SAK                 ------------------------------------------------------------
8829_Tthe_PLK-Unclassified    ------------------------------------------------------------
SAK_Spur_SAK                  ------------------------------------------------------------
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   ------------------------------------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ------------------------------------------------------------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 ---------------------------------------AES------------------
PLK3_Hsap_PLK2                ---------------------------------------ATD------------------
PLK2_Hsap_PLK2                ---------------------------------------MTD------------------
PLK1_Hsap_PLK1                ---------------------------------------ISD------------------
polo_Dmel_PLK1                ---------------------------------------IID------------------
SAK_Dmel_SAK                  ---------------------------------------ARC------------------
PLK5_Mmus_PLK2                ---------------------------------------LTD------------------
PLK4_Mmus_SAK                 ---------------------------------------AES------------------
PLK3_Mmus_PLK2                ---------------------------------------ATD------------------
PLK2_Mmus_PLK2                ---------------------------------------MTD------------------
PLK1_Mmus_PLK1                ---------------------------------------ISD------------------
plk-2_Cele_PLK1               ---------------------------------------LRN------------------
plk-1_Cele_PLK1               ---------------------------------------LTN------------------
F55G1.8_Cele_PLK1             ---------------------------------------FRK------------------
CDC5_Scer_PLK1                ---------------------------------------IKD------------------
zyg-1_Cele_SAK                ---------------------------------------AQR------------------
PLK_Ddis_PLK1                 ---------------------------------------MTE------------------
8635_Tthe_SAK                 KQFLYPLMIYTQVSDELSFKDIEASLDYDIKGANGFVCKIEDFKSKECYNSNEAKKYYVY
18358b_Tthe_PLK-Unclassified  ---------------------------------------FTN------------------
18380_Tthe_PLK-Unclassified   ---------------------------------------VIA------------------
21183_Tthe_SAK                ---------------------------------------IEE------------------
22503_Tthe_PLK-Unclassified   ---------------------------------------AKD------------------
5034_Tthe_SAK                 ---------------------------------------VKS------------------
8829_Tthe_PLK-Unclassified    ---------------------------------------VTN------------------
SAK_Spur_SAK                  ---------------------------------------AKT------------------
PLK1_Spur_PLK1                ---------------------------------------LTD------------------
PLK2_Spur_PLK2                ---------------------------------------LTH------------------
n1170_Tthe_PLK-Unclassified   ---------------------------------------VTN------------------
n808_Tthe_PLK-Unclassified    ---------------------------------------VTN------------------
CC1G_07437_Ccin_PLK1          ---------------------------------------VQD------------------
AqueK200_Aque_PLK1            ---------------------------------------LIC------------------
AqueK201_Aque_SAK             ---------------------------------------AKC------------------
GK066_Glam_PLK-Unclassified   ---------------------------------------FHD------------------


PLK4_Hsap_SAK                 --IHT--GLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKH-PSILELYNYFEDSNYVY
PLK3_Hsap_PLK2                --TET--GSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQH-RHIVRFSHHFEDADNIY
PLK2_Hsap_PLK2                --LTN--NKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHH-KHVVQFYHYFEDKENIY
PLK1_Hsap_PLK1                --ADT--KEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAH-QHVVGFHGFFEDNDFVF
polo_Dmel_PLK1                --VET--DDVFAGKIVSKKLMIKHNQKEKTAQEITIHRSLNH-PNIVKFHNYFEDSQNIY
SAK_Dmel_SAK                  --LHT--HQDVAIKMIDKKLIQGTGLTNRVRQEVEIHSRLKH-PSVLQLYTFFQDANYVY
PLK5_Mmus_PLK2                --MST--SAVFALKVVPRGGAGRLRLRGKVEREIALHSRLRH-RNIVAFHAHFADRDHVY
PLK4_Mmus_SAK                 --IHT--GLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKH-PSVLELYNYFEDNNYVY
PLK3_Mmus_PLK2                --TES--GIAYAVKVIPQSRVAKPHQREKILNEIELHRDLQH-RHIVRFSHHFEDADNIY
PLK2_Mmus_PLK2                --LTN--NKVYAAKIIPHSRVAKPHQREKIDKEIELHRLLHH-KHVVQFYHYFEDKENIY
PLK1_Mmus_PLK1                --ADT--KEVFAGKIVPKSLLLKPHQKEKMSMEISIHRSLAH-QHVVGFHDFFEDSDFVF
plk-2_Cele_PLK1               --KST--GELFAGKVVPKALLIKQYQRDKMAQEVQIHRNLQH-RNVVKLYHFFEDKSNVY
plk-1_Cele_PLK1               --RAT--REVVAGKVVPKSMLVKQYQRDKMTQEVQIHRELGH-INIVKLFNFFEDNLNVY
F55G1.8_Cele_PLK1             --LDC--NDRLAVKVVPKVILLKSTAREKLTREVEIHRQLSH-RNIVQFHHFFEDSQNVY
CDC5_Scer_PLK1                ---DS--GEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSH-PNIVQFIDCFEDDSNVY
zyg-1_Cele_SAK                ---EN--GEKVAIKRIDKK-----VPKNRVWTEIQTMKELKKSKYVVEFYEDFVEDGYTY
PLK_Ddis_PLK1                 --VET--NRIYAAKIIPKSTLQKTRARSKLKSEIKIHSSLSH-ENIVKFEHCFENEENVY
8635_Tthe_SAK                 LLLTY--TKQKAMKVVDKKRKDIQNVMKRLDQEIKIQKELDH-PNIIKLFKHFEDDQNHY
18358b_Tthe_PLK-Unclassified  --LER--KQVLAAKVIPKSSLTKSRARQKLMSEIRIHKSLNH-RNIVKFQHFFEDQENVY
18380_Tthe_PLK-Unclassified   --LDTDPKAIFAAKIIPKSTLTKSRQRVKLISEIKIHKSLHH-KNIVQFEHVFEDHDNVY
21183_Tthe_SAK                --YKS--G------------------------SLYLHSQLDH-PNIVKILKRFEDNEYVY
22503_Tthe_PLK-Unclassified   --ISS--NEQYAIKVVDKSSLEKDSFKEKLNQEIKIQKSLNH-ENVVKYYTSFEDSQNVY
5034_Tthe_SAK                 --IKT--KKEYAIKVVDKQSQYYKSAYKRLKNEIEIHLDLKH-KNIVKMIKSFEDSENLY
8829_Tthe_PLK-Unclassified    --LET--KKIIAAKIIPKQTLTKNRARQKLISEIKIHKSLNH-QHVVAFEHVFEDHENVY
SAK_Spur_SAK                  --IST--GQEVAIKMIDKKLMQSSGMATRVKNEVEIHCQLKH-PSILELYSYFEDNNYVY
PLK1_Spur_PLK1                --DAT--KQIFAGKVVSKALLVKPHQKDKMTMEIHIHKSLHH-RHVVGFHSFFEDKENVY
PLK2_Spur_PLK2                --LDT--HYVYAGKIVPKERISKPSQREKMEREIAVHAQLRH-PHIVGFHKHFQDAENIY
n1170_Tthe_PLK-Unclassified   --LEN--KKVMAAKIIPKSTLVKNRARQKLISEIKIHKSLHH-NNIVKFEHVFEDHDNVY
n808_Tthe_PLK-Unclassified    --LEN--KKVMAAKIIPKSTLVKNRARQKLISEIKIHKSLHH-NNIVKFEHVFEDHDNVY
CC1G_07437_Ccin_PLK1          --PR---GSRLACKVVTKSALKTKKAKTKLYAEIKIHRSLDH-PNIVTFIDCFEDEDNVY
AqueK200_Aque_PLK1            --EET--GTVYAGKIVAKELLVKPHQKEKMTQEIEIHRSLSH-KHVVGFHGFFDDSNNVY
AqueK201_Aque_SAK             --KRT--KKEVAIKMIDKKLMVKKGMTERVKNEVKIHSHLKH-PSILELYDFFEDSNYVY
GK066_Glam_PLK-Unclassified   --VNS--DSSYACKITPRSALQKKKYYDKFVTEVTIHRGLVH-PNICRVLNVFKDQMNYY
                                                              .:     : :   :      * :    :

PLK4_Hsap_SAK                 LVLEMCHNG----EMNRYL-------KNRVKPFSENEARHFMHQIITGMLYLHSHGILHR
PLK3_Hsap_PLK2                IFLELCSRK----SLAHIW-------KAR-HTLLEPEVRYYLRQILSGLKYLHQRGILHR
PLK2_Hsap_PLK2                ILLEYCSRR----SMAHIL-------KAR-KVLTEPEVRYYLRQIVSGLKYLHEQEILHR
PLK1_Hsap_PLK1                VVLELCRRR----SLLELH-------KRR-KALTEPEARYYLRQIVLGCQYLHRNRVIHR
polo_Dmel_PLK1                IVLELCKKR----SMMELH-------KRR-KSITEFECRYYIYQIIQGVKYLHDNRIIHR
SAK_Dmel_SAK                  LVLELAHNG----ELHRYM-------NHIARPFTETEAASILKQVVAGLLYLHSHNIMHR
PLK5_Mmus_PLK2                MVLEYCSRQVPLQSLAHVL-------KVR-RTLTEPEVRYYLRGLVSGLRYLHQQRIVHR
PLK4_Mmus_SAK                 LVLEMCHNG----EMNRYL-------KNRMKPFSEREARHFMHQIITGMLYLHSHGILHR
PLK3_Mmus_PLK2                IFLELCSRK----SLAHIW-------KAR-HTLLEPEVRYYLRQILSGLKYLHQRGILHR
PLK2_Mmus_PLK2                ILLEYCSRR----SMAHIL-------KAR-KVLTEPEVRYYLRQIVSGLKYLHEQEILHR
PLK1_Mmus_PLK1                VVLELCRRR----SLLELH-------KRR-KALTEPEARYYLRQIVLGCQYLHRNQVIHR
plk-2_Cele_PLK1               ITLELCPRR----SLMELH-------KRR-KAVTEPEARYFTYQIVEGVLYLHNLKIVHR
plk-1_Cele_PLK1               ITLELCARR----SLMELH-------KRR-KAVTEPEARYFTHQIVDGVLYLHDLNIIHR
F55G1.8_Cele_PLK1             FTLELCSKN----SLMELN-------KQR-GPLTEHEARFYTIQVAEGVKHLHNLQIIHR
CDC5_Scer_PLK1                ILLEICPNG----SLMELL-------KRR-KVLTEPEVRFFTTQICGAIKYMHSRRVIHR
zyg-1_Cele_SAK                IVMELCEGG----SLQAYV-------REH-GALDDATAVHVLRQLISAVSFMHRVNVIHR
PLK_Ddis_PLK1                 ILLELCNQK----TVMDIH-------KKR-KYLMEYETKYYVYQVIMAVQYLHNNNIIHR
8635_Tthe_SAK                 LIMELAQNG----EIKDYL-------NIN-K----------PYQLACGIKYLHDKDIVHR
18358b_Tthe_PLK-Unclassified  ILLEMCTNQ----TMNELI-------RRR-KRLTELEVQCYLLQILYSIKYLHDNRVIHR
18380_Tthe_PLK-Unclassified   ILLELCPYQ----TLNELI-------KRR-KRITEYETQIYVMQIVNALKYLHQNKIIHR
21183_Tthe_SAK                MMLEYCPGG----SLFDYIVYINFQLFEK-TRLNEDEARDISYQIVQGLEYLHKNKIIHR
22503_Tthe_PLK-Unclassified   IVLEYCSNQ----EL---L-------DRR-KRLTEIEVKSHLFQIIQSLKYIHSKGVIHR
5034_Tthe_SAK                 LVMEYCEGG----DLFHYL-------KHH-KKLSETEAKRITYKLAEGLKYLHDKSIIHR
8829_Tthe_PLK-Unclassified    ILLELCTNH----TLNELI-------KRR-KRLTELEVQCYVVQIVNALKYLHSHKVIHR
SAK_Spur_SAK                  LVLELAQNG----ELLRYL-------KKKARVFGEEEARQFLEEIVIGLLYLHSHGILHR
PLK1_Spur_PLK1                VLLELCRRR----SLMELH-------KRR-KAITEPETRYFMRQCILACQYLSKTKVIHR
PLK2_Spur_PLK2                ILLELCRHK----SLLHML-------KLR-KHLTEPEVRYFMLQIIEGVRYLHSHCVIHR
n1170_Tthe_PLK-Unclassified   ILLELCPHQ----TLNELI-------KRR-KRITELETLCYTVQIVQALKYLHQNRVIHR
n808_Tthe_PLK-Unclassified    ILLELCPHQ----TLNELI-------KRR-KRITELETLCYTVQIVQALKYLHQNRVIHR
CC1G_07437_Ccin_PLK1          ITLELCPSG----SLMDML-------RRR-RRFTEPETRFFMVQLIGACHYMHTHQVIHR
AqueK200_Aque_PLK1            ILLELCKRR----SLMELH-------KRR-KALTEPEVRYLFRQTVLAVDYLHDVKVIHR
AqueK201_Aque_SAK             LILEFCQNG----ELNRYL-------KHRQKSLSE-DERIILNQVVKGLIYLHSFNIVHR
GK066_Glam_PLK-Unclassified   IILEKCNGG----TLTDLI-------RRR-KHLTETEARFFSKRILNALWYLHDLYIIHR
                              . :* .        :                                .  .:    ::**

PLK4_Hsap_SAK                 DLTLSNLLLTR----NMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEI---------
PLK3_Hsap_PLK2                DLKLGNFFITE----NMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEV---------
PLK2_Hsap_PLK2                DLKLGNFFINE----AMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEV---------
PLK1_Hsap_PLK1                DLKLGNLFLNE----DLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEV---------
polo_Dmel_PLK1                DLKLGNLFLND----LLHVKIGDFGLATRIEYEGERKKTLCGTPNYIAPEI---------
SAK_Dmel_SAK                  DISLSNLLLSR----EMHVKIADFGLATQLKRPDERHMTMCGTPNYISPEV---------
PLK5_Mmus_PLK2                DLKPSNFFLNK----NMEVKIGDLGLAARVGPAGRCHRVLCGTPNFQAPEV---------
PLK4_Mmus_SAK                 DLTLSNILLTR----NMNIKIADFGLATQLNMPHEKHYTLCGTPNYISPEI---------
PLK3_Mmus_PLK2                DLKLGNFFITD----NMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEV---------
PLK2_Mmus_PLK2                DLKLGNFFINE----AMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEV---------
PLK1_Mmus_PLK1                DLKLGNLFLNE----DLEVKIGDFGLATKVEYEGERKKTLCGTPNYIAPEV---------
plk-2_Cele_PLK1               DLKLGNLFLND----ELQVKIGDFGLATTCDN-DERKKTLCGTPNYIAPEV---------
plk-1_Cele_PLK1               DMKLGNLFLND----DLVVKIGDFGLATTVNG-DERKKTLCGTPNYIAPEV---------
F55G1.8_Cele_PLK1             DLKLGNLFLNE----HLQVKIGDFGLATFCEK-NEKKMTRGGTPNYIAPEV---------
CDC5_Scer_PLK1                DLKLGNIFFDS----NYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEV---------
zyg-1_Cele_SAK                DLSAGNVFIKDSKKKKMTVKLGDFGLATTLGR-GETTCTIVGTPGFIAPQV---------
PLK_Ddis_PLK1                 DLKLGNLFI-D----NMRIKLGDFGLSTKVEH-GERKKTICGTPNYIAPEI---------
8635_Tthe_SAK                 DLKLNNVLLS-----NGKIKIADFGLATKVNDENPECNTMCGTANYLSPEI---------
18358b_Tthe_PLK-Unclassified  DLKLGNLFLSD----KMEIKLGDFGLATKLEYDGERKRTICGTPNYIAPEI---------
18380_Tthe_PLK-Unclassified   DLKLGNLFLGD----NMTLKIGDFGLATKIEYEGEKKKTVCGTPNYIAPEI---------
21183_Tthe_SAK                DLKPGNILLTG----NNSVKICDFGLAVRVTNYESERDTFCGTPNYIAPEK---------
22503_Tthe_PLK-Unclassified   DLKIANIFLND----KMVVKLADFGLSAMMKN-AQKRKTVCGTPNYIAPEV---------
5034_Tthe_SAK                 DLKLGNVLLSS----DHQVKICDFGLAVRLNGNEQEKNTICGTPNYISPEI---------
8829_Tthe_PLK-Unclassified    DLKLGNLFLNE----KMEIKLGDFGLATKLEFDGEKKHTICGTPNYIAPEI---------
SAK_Spur_SAK                  DLTLANILLTR----DMHCKIADFGLAAQLKLPEEQHYTMCGTPNYISPEI---------
PLK1_Spur_PLK1                DLKLGNLFIDD----NMELKVGDFGLATKVDFSGERKKTLCGTPNYIAPEV---------
PLK2_Spur_PLK2                DLKLGNMFLTD----TMGVKIGDFGLAAKLEFEGDRKRTMCGTPNYIAPEV---------
n1170_Tthe_PLK-Unclassified   DLKLGNLFVGE----KMEIKLGDFGLATKLEFDGEKKRTICGTPNYIAPEI---------
n808_Tthe_PLK-Unclassified    DLKLGNLFVGE----KMEIKLGDFGLATKLEFDGEKKRTICGTPNYIAPEI---------
CC1G_07437_Ccin_PLK1          DLKLGNLFLDA----NMNVKVGDFGLAALIENPGERKKTICGTPNYIAPEV---------
AqueK200_Aque_PLK1            DLKLGNLFLND----DIEIKLGDFGLATRLEEDGERKKTLCGTPNYIAPEV---------
AqueK201_Aque_SAK             DLSLSNILLTS----SMDIKIADFGLSVTLDLPGDKHHTLCGTPNYIAPYVICCYEGCFL
GK066_Glam_PLK-Unclassified   DIKTSNIFLME----DFDVKVGDFGLAVKCETPEELHWTMCGTPNFLPSEV---------
                              *:.  *.:.          *: *:**:.          .  **..: ..

PLK4_Hsap_SAK                 --------AT---------------------------------RSAHGLESDVWSLGCMF
PLK3_Hsap_PLK2                --------LL---------------------------------RQGHGPEADVWSLGCVM
PLK2_Hsap_PLK2                --------LN---------------------------------KQGHGCESDIWALGCVM
PLK1_Hsap_PLK1                --------LS---------------------------------KKGHSFEVDVWSIGCIM
polo_Dmel_PLK1                --------LT---------------------------------KKGHSFEVDIWSIGCVM
SAK_Dmel_SAK                  --------VS---------------------------------RTSHGLPADVWSVGCML
PLK5_Mmus_PLK2                --------VS---------------------------------RNGHSCKSDIWALGCIM
PLK4_Mmus_SAK                 --------AT---------------------------------RSAHGLESDIWSLGCMF
PLK3_Mmus_PLK2                --------LL---------------------------------RQGHGPEADVWSLGCVM
PLK2_Mmus_PLK2                --------LN---------------------------------KQGHGCESDIWALGCVM
PLK1_Mmus_PLK1                --------LS---------------------------------KKGHSFEVDVWSIGCIM
plk-2_Cele_PLK1               --------LN---------------------------------KIGHSFEVDLWAIGCIL
plk-1_Cele_PLK1               --------LN---------------------------------KAGHSFEVDIWAVGCIL
F55G1.8_Cele_PLK1             --------LN---------------------------------ETGHAFEVDIWAIGCIL
CDC5_Scer_PLK1                --------LMG-------------------------------KHSGHSFEVDIWSLGVML
zyg-1_Cele_SAK                --------YD---------------------------------Q-EYTQSADVYSLGAVL
PLK_Ddis_PLK1                 --------LD--------------------------------NSNGHSYEVDVWSIGIIL
8635_Tthe_SAK                 --------LN---------------------------------SKGYGKKTDIWSFGCIL
18358b_Tthe_PLK-Unclassified  --------LEA-------------------------------KETGHSYEVDVWSFGVIA
18380_Tthe_PLK-Unclassified   --------LE--------------------------------GKDGHSYEVDMWSLGVII
21183_Tthe_SAK                ----------------------------------------------YGIQSDCWSFGCIL
22503_Tthe_PLK-Unclassified   --------LK---------------------------------NQGHDYLVDNWAIGVIV
5034_Tthe_SAK                 --------LN---------------------------------KQPYGMKIDCWSFGCIL
8829_Tthe_PLK-Unclassified    --------LD--------------------------------GKTGHSYQVDIWSLGVII
SAK_Spur_SAK                  --------AT---------------------------------RGPHGLQSDVWSLGCML
PLK1_Spur_PLK1                --------LS---------------------------------KKGHSYEVDLWSLGCIM
PLK2_Spur_PLK2                --------LG---------------------------------KIGHSFEADVWALGCIM
n1170_Tthe_PLK-Unclassified   --------LD--------------------------------GRVGHSYEVDIWSLGVIL
n808_Tthe_PLK-Unclassified    --------LD--------------------------------GRVGHSYEVDIWSLGVIL
CC1G_07437_Ccin_PLK1          --------LFD-------------------------------TANGHSFEVDIWSIGVIL
AqueK200_Aque_PLK1            --------LT---------------------------------KKGHSYEVDIWSLGCIL
AqueK201_Aque_SAK             IFIFCREVAK---------------------------------REAHGLESDIWSLGCMV
GK066_Glam_PLK-Unclassified   --------IYSHIMKRKASGRGPDPNLDEDCVNLCHQLLPAYSGQGHSFSADMWSFGCLV
                                                                            :    * ::.* :

PLK4_Hsap_SAK                 YTLLIGRPPFDTDTVKNTLNKVV-LAD--YEMPS--FLSIEAKDLIHQLLRRNPADRLSL
PLK3_Hsap_PLK2                YTLLCGSPPFETADLKETYRCIK-QVH--YTLPAS--LSLPARQLLAAILRASPRDRPSI
PLK2_Hsap_PLK2                YTMLLGRPPFETTNLKETYRCIR-EAR--YTMPSS--LLAPAKHLIASMLSKNPEDRPSL
PLK1_Hsap_PLK1                YTLLVGKPPFETSCLKETYLRIK-KNE--YSIPKH--INPVAASLIQKMLQTDPTARPTI
polo_Dmel_PLK1                YTLLVGQPPFETKTLKDTYSKIK-KCE--YRVPSY--LRKPAADMVIAMLQPNPESRPAI
SAK_Dmel_SAK                  YTLLVGRPPFETDAVQSTLNKVV-MSE--YIMPA--HLSYEAQDLINKLLKKLPHERITL
PLK5_Mmus_PLK2                YTVLTGTPPFAAAPLSEMYQNIR-DGH--YLEPTH--LSPSARSLIARLLAPDPAERPSL
PLK4_Mmus_SAK                 YTLLIGRPPFDTDTVKNTLNKVV-LAD--YEMPA--FLSREAQDLIHQLLRRNPADRLSL
PLK3_Mmus_PLK2                YTLLCGSPPFETADLKETYRCIK-QVH--YTLPAS--LSLPARQLLAAILRASPRDRPSI
PLK2_Mmus_PLK2                YTMLLGRPPFETTNLKETYRCIR-EAR--YTMPSS--LLAPAKHLIASMLSKNPEDRPSL
PLK1_Mmus_PLK1                YTLLVGKPPFETSCLKETYLRIK-KNE--YSIPKH--INPVAASLIQKMLQTDPTARPTI
plk-2_Cele_PLK1               YILLFGHPPFESKSLEETYSRIK-NNN--YVIPTS--ASAAASQLIRVLLDPVPSRRPNA
plk-1_Cele_PLK1               YILLFGQPPFESKSLEETYSRIR-HNN--YTIPSI--ATQPAASLIRKMLDPEPTRRPTA
F55G1.8_Cele_PLK1             YVLLFGSPPFESRRVQETYVRIK-NND--YVVPE--NASPTANRLIRSLLDPVPDRRPTA
CDC5_Scer_PLK1                YALLIGKPPFQARDVNTIYERIK-CRD--FSFPRDKPISDEGKILIRDILSLDPIERPSL
zyg-1_Cele_SAK                YTMLTARNPPPK------------------GLPPTCGMSPNAARLVEQMMDTDAKKRIPL
PLK_Ddis_PLK1                 YTLLIGKPPFETSDVKHTYQRIK-QNQ--YSFPDEPIISHYGKSLIISILNPVPEQRPNL
8635_Tthe_SAK                 YALCSGNLPFFSGNPSQTIQNIK-EGK--WQLPQN--ISDNVKDLLSNTLNWDQNSRFSI
18358b_Tthe_PLK-Unclassified  YTLLIGKPPFETNDVKSTYKKIR-TNE--YSFPEQIQISSAAKNMIKKILTTDPSKRPTI
18380_Tthe_PLK-Unclassified   YTLLIGKPPFETKDVRTTYKRIK-MNN--YCFPEQIQISDNAKSIITSILNLNPQKRLTL
21183_Tthe_SAK                YTIATGRPPFETVSIQQTLKMLQKKNK--VEYPSH--LSKSLVDLIDHILDWNQDTRYNI
22503_Tthe_PLK-Unclassified   YTFLIGKPPFEEKEVENTLRNIK-ANR--YSFPENCTISKEAKDFIQKILVPNPDQRLTM
5034_Tthe_SAK                 YALIVGHPPFQGQDIVQTLKKVT-SQEQFFELPNN--ISDNLKDLLVNIINWNQDSRFTI
8829_Tthe_PLK-Unclassified    YTLLIGKPPFETPDVKTTYKKIR-NIS--YGFPENVPISDQARGLITRILNIDPQRRPTL
SAK_Spur_SAK                  YTFLTGTPPFDTEAVKTTLNKVM-LAE--YIIPT--HISMEAKDLINKMLRKDPTERIGL
PLK1_Spur_PLK1                YTLLVGKPPFETQSLKDTYQRIK-RNE--YRVPSH--VSTPARNLIVKLLKNDPTQRPHI
PLK2_Spur_PLK2                YTMLVGRPPFETSSLKETYARIK-HNK--YHFPET--LSPVAKEIISDLLSSDPEERPPL
n1170_Tthe_PLK-Unclassified   YTLLIGKPPFETHDVKTTYRKIK-SNQ--YSFPDHAPIPDSAKALIQLILQQDPAKRPTL
n808_Tthe_PLK-Unclassified    YTLLIGKNNCIQL----SFRRSR-K-Q--YSR----------------------------
CC1G_07437_Ccin_PLK1          YTLVIGRPPFQTKEVKEIYKRIR-DNE--YEFPAERAISTAVKVLIQQILTPDPSQRPTL
AqueK200_Aque_PLK1            YTLLVGKPPFETKTLKDTYQRIK-RNE--YHIPHY--VGPEARTLISNLLRPNPANRPTA
AqueK201_Aque_SAK             YTMLVGTPPFDTDDVQSTLDNVV-NGD--FDIPQ--YITTNCTSLNL--HVYHPSKRLTL
GK066_Glam_PLK-Unclassified   FSMIYGRPPFEAADIKTTYKRIV-RCD--FSFPGSISVSEDLKNFIKGLLTPDPRKRFTV
                              : .  .

PLK4_Hsap_SAK                 SSVLDHPFMSRN--SSTK-----SKDLGT--V----------------------------
PLK3_Hsap_PLK2                DQILRHDFFTKG--YTPD-----RLPISS--C----------------------------
PLK2_Hsap_PLK2                DDIIRHDFFLQG--FTPD-----RLSSSC--C----------------------------
PLK1_Hsap_PLK1                NELLNDEFFTSG--YIPA-----RLPITC--L----------------------------
polo_Dmel_PLK1                GQLLNFEFLKGS--KVPM-----FLPSSC--L----------------------------
SAK_Dmel_SAK                  EAVLCHPFMLKC--SNGGHSAPGALNVFS--Q----------------------------
PLK5_Mmus_PLK2                DHLLQDDFFSQG--FTPE-----RLPPHS--C----------------------------
PLK4_Mmus_SAK                 SSVLDHPFMSRN--PSPK-----SKDVGT--V----------------------------
PLK3_Mmus_PLK2                EQILRHDFFTKG--YTPD-----RLPVSS--C----------------------------
PLK2_Mmus_PLK2                DDIIRHDFFLQG--FTPD-----RLSSSC--C----------------------------
PLK1_Mmus_PLK1                HELLNDEFFTSG--YIPA-----RLPITC--L----------------------------
plk-2_Cele_PLK1               RAVCRDHFFKSG--FMPA-----RLPVSC--L----------------------------
plk-1_Cele_PLK1               KQVQRDGFFKSG--FMPT-----RLPVSC--L----------------------------
F55G1.8_Cele_PLK1             EAVLLDQFFKTT--IEPT-----YPPVHQ--Q----------------------------
CDC5_Scer_PLK1                TEIMDYVWFRGT---FPP-----SIPSTV--M----------------------------
zyg-1_Cele_SAK                TQIVLSEFMYEN--TNEN-----AVIFSR-------------------------------
PLK_Ddis_PLK1                 TQILEHDFFTYS--PIPK-----YLPVSS--L----------------------------
8635_Tthe_SAK                 EQVLSHKFYEKKH--KQS-----IIIFNQ--GADAISNQ---------------------
18358b_Tthe_PLK-Unclassified  NELFNDDFFKTG-GSIPK-----LLPVST--L----------------------------
18380_Tthe_PLK-Unclassified   DELLEHPFMQGT-ALNPE-----NLPISS--L----------------------------
21183_Tthe_SAK                SQIKSHPFYNKSK--QNT-----HENEYK--L----------------------------
22503_Tthe_PLK-Unclassified   DQMLQHPFMKSEEYYIPK-----TFPIST--L----------------------------
5034_Tthe_SAK                 DQILMHPFYEEMR--QKS-----VKQRQE--EEESLSFFNSIRSVKGEDQRINVHQNGVK
8829_Tthe_PLK-Unclassified    DEIMSSSFLNTG-GTIPK-----VLPLAT--L----------------------------
SAK_Spur_SAK                  STVLDHPFMDKT--RFNGTK---NRPLSKRPV----------------------------
PLK1_Spur_PLK1                DILLQDEFFTTG--YLPP-----QLPTTC--L----------------------------
PLK2_Spur_PLK2                EVVIDHEFFTQG--FVPE-----TLSPTA--C----------------------------
n1170_Tthe_PLK-Unclassified   DEILAHPFINNG-GTIPR-----LLPVST--L----------------------------
n808_Tthe_PLK-Unclassified    ---LAWPYFNK-------------------------------------------------
CC1G_07437_Ccin_PLK1          HEIIEDTFFTHG--TVPA-----FIPTSA--H----------------------------
AqueK200_Aque_PLK1            AEILKDPFFTCG--HMPV-----RLPVSC--L----------------------------
AqueK201_Aque_SAK             QQVLYHSFTKGV--QQE-----NVLQKRT--L----------------------------
GK066_Glam_PLK-Unclassified   KECLDHSWLNPSKYFIPE-----SLPPRI--I----------------------------
                                     :

PLK4_Hsap_SAK                 -------------------EDS-----------IDSGHATISTAITASSSTSIS------
PLK3_Hsap_PLK2                -------------------VTV-----------PDLTPP------NPA--RS--------
PLK2_Hsap_PLK2                -------------------HTV-----------PDFHLS------SPA--KN--------
PLK1_Hsap_PLK1                -------------------TIP-----------PRFSIA------PSS--LD--------
polo_Dmel_PLK1                -------------------TMA-----------PRIGSN------DTI--ED--------
SAK_Dmel_SAK                  -------------------S-------------MESGDSGIITFASSDSRNSQQ------
PLK5_Mmus_PLK2                -------------------HSP-----------PVFAFP------PPL--GR--------
PLK4_Mmus_SAK                 -------------------EDS-----------MDSGHATLSTTITASSGTSLS------
PLK3_Mmus_PLK2                -------------------VTV-----------PDLTPP------NPA--RS--------
PLK2_Mmus_PLK2                -------------------HTV-----------PDFHLS------SPA--KN--------
PLK1_Mmus_PLK1                -------------------TIP-----------PRFSIA------PSS--LD--------
plk-2_Cele_PLK1               -------------------TMV-----------PHLNDD------EY----A--------
plk-1_Cele_PLK1               -------------------TMV-----------PKFGGH------ETS--MM--------
F55G1.8_Cele_PLK1             -------------------L-------------------------HKE--QD--------
CDC5_Scer_PLK1                -------------------SEA-----------PNFEDI------PEE--QS--------
zyg-1_Cele_SAK                -------------------E-------------------------HSR--DGRR------
PLK_Ddis_PLK1                 -------------------TTA-----------PSQSTI------NQN--MG--------
8635_Tthe_SAK                 ---------------QNKLSTP--NKVLLDWTSPRFNAP---IHLQQK--SQ-SSQ----
18358b_Tthe_PLK-Unclassified  -------------------ACP-----------PSASYT------RQF--LP--------
18380_Tthe_PLK-Unclassified   -------------------VVP-----------FQKPKK------EAL--KE--------
21183_Tthe_SAK                -------------------QNP--MTF----APPQPFQM------EQS--VN--------
22503_Tthe_PLK-Unclassified   -------------------ALP-----------PTANYL------RKL--RK--------
5034_Tthe_SAK                 KIDIKYQDNFFNQLEHKEGSMP--KKS----NSP--TNI------HER--KN---QMIYK
8829_Tthe_PLK-Unclassified    -------------------ACP-----------PSASYT------KQF--LP--------
SAK_Spur_SAK                  -------------------ESS-----------LDSGLATMATISS--SHTSNR------
PLK1_Spur_PLK1                -------------------TMA-----------PRFQVP------VSS------------
PLK2_Spur_PLK2                -------------------VTA-----------PDFPIT------KVL--IS--------
n1170_Tthe_PLK-Unclassified   -------------------TTA-----------PNTSYI------KQY--AP--------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          -------------------DAA-----------PDFRHI------SRS--AS--------
AqueK200_Aque_PLK1            -------------------TTT-----------PHFKKA------AES--A---------
AqueK201_Aque_SAK             -------------------SL------------------------TTP------------
GK066_Glam_PLK-Unclassified   -------------------SEPYEV--------PPLCSA------SPT--RN--------


PLK4_Hsap_SAK                 ---------------------------------GS---L------FDKR-----------
PLK3_Hsap_PLK2                ---------------------------------L--FA----------------------
PLK2_Hsap_PLK2                ---------------------------------F--FK----------------------
PLK1_Hsap_PLK1                ---------------------------------PS-NR----------------------
polo_Dmel_PLK1                ---------------------------------SM-HR----------------------
SAK_Dmel_SAK                  ---------------------------------I--------------R-----------
PLK5_Mmus_PLK2                ---------------------------------L--FR----------------------
PLK4_Mmus_SAK                 ---------------------------------GS---L------LD-R-----------
PLK3_Mmus_PLK2                ---------------------------------L--FA----------------------
PLK2_Mmus_PLK2                ---------------------------------F--FK----------------------
PLK1_Mmus_PLK1                ---------------------------------PS-SR----------------------
plk-2_Cele_PLK1               ---------------------------------EE-NV----------------------
plk-1_Cele_PLK1               ---------------------------------EE-NV----------------------
F55G1.8_Cele_PLK1             ---------------------------------VK---Y------F--------------
CDC5_Scer_PLK1                ---------------------------------LV---N------F--------------
zyg-1_Cele_SAK                ---------------------------------QR---S------R--------------
PLK_Ddis_PLK1                 ---------------------------------RPLSEK------T--------------
8635_Tthe_SAK                 ---------------------------------KK---N---------------------
18358b_Tthe_PLK-Unclassified  ---------------------------------ST---Q------I--------------
18380_Tthe_PLK-Unclassified   ---------------------------------KS---N------N--------------
21183_Tthe_SAK                ---------------------------------QN---N---------------------
22503_Tthe_PLK-Unclassified   ---------------------------------SE---S---------------------
5034_Tthe_SAK                 NDQIAALKNNKIQNEDLNIMSNNLNQIQYKKQSQN---NLVKQNDK--------------
8829_Tthe_PLK-Unclassified    ---------------------------------QG---N------A--------------
SAK_Spur_SAK                  ---------------------------------TS-----------SRS-----------
PLK1_Spur_PLK1                ------------------------------------GR----------------------
PLK2_Spur_PLK2                ---------------------------------DR-KG----------DLVTNEFCRLKR
n1170_Tthe_PLK-Unclassified   ---------------------------------SA---S------N--------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ---------------------------------EANLKR---LRRY--ALLDTDFNN--T
AqueK200_Aque_PLK1            ---------------------------------VS-GR----------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ---------------------------------M--QM----------------------


PLK4_Hsap_SAK                 ----------RLLIGQPLPNKMTVFPKNKSSTDFSSSG--DGN---SFYTQWGN--QETS
PLK3_Hsap_PLK2                ----------K-----VTK---SL------------------------------------
PLK2_Hsap_PLK2                ----------K-----AAA---AL------------------------------------
PLK1_Hsap_PLK1                ----------K-----PLT---VL------------------------------------
polo_Dmel_PLK1                ----------K-----PLM---EM------------------------------------
SAK_Dmel_SAK                  ------------SVENSGPQ----------------------------------------
PLK5_Mmus_PLK2                ----------K-----VGQ---LL------------------------------------
PLK4_Mmus_SAK                 ----------RLLVGQPLPNKITVFQKNKNSSDFS-SG--DGS---NFCTQWGNPEQEAN
PLK3_Mmus_PLK2                ----------K-----VTK---SL------------------------------------
PLK2_Mmus_PLK2                ----------K-----AAA---AL------------------------------------
PLK1_Mmus_PLK1                ----------K-----PLK---VL------------------------------------
plk-2_Cele_PLK1               ----------S-----PSG---TI------------------------------------
plk-1_Cele_PLK1               ----------A-----PRG---VD------------------------------------
F55G1.8_Cele_PLK1             ----------A-----PIN-----------------------------------------
CDC5_Scer_PLK1                ----------K-----DCM-----------------------------------------
zyg-1_Cele_SAK                ----------E-----PVR-----------------------------------------
PLK_Ddis_PLK1                 ----------------------NIV--N--------------------------------
8635_Tthe_SAK                 ----------------------KRIS-N--------------------------------
18358b_Tthe_PLK-Unclassified  ----------------------SLST-N--------------------------------
18380_Tthe_PLK-Unclassified   ----------------------QIVQ-D--------------------------------
21183_Tthe_SAK                ----------------------KNIQ----------------------------------
22503_Tthe_PLK-Unclassified   ----------------------VLAP----------------------------------
5034_Tthe_SAK                 ----------------------QILN----------------------------------
8829_Tthe_PLK-Unclassified    -----------------------LKL-N--------------------------------
SAK_Spur_SAK                  ----------RPMRALPLSTLTPVISEGEGSRGQ-VKGHHHGDGIGSSWNQYDR--HPPS
PLK1_Spur_PLK1                ----------R-----PLL---EV------------------------------------
PLK2_Spur_PLK2                ESTLQRRDVTA-----PLS---EL------------------------------------
n1170_Tthe_PLK-Unclassified   -----------------------IKA-N--------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          PSPVQNATTRN-----ITS---SIAQ-Q--------------------------------
AqueK200_Aque_PLK1            ----------K-----PLS---DR------------------------------------
AqueK201_Aque_SAK             -----------------------VIATYRGDCQFH-------------------------
GK066_Glam_PLK-Unclassified   ----------T-----INM---AK------------------------------------


PLK4_Hsap_SAK                 NSGRGRVIQ-------------DAEERPH-----------SRYLRRAYS-----------
PLK3_Hsap_PLK2                ------------------------------------------------------------
PLK2_Hsap_PLK2                ------------------------------------------------------------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  -----QVLP-------------Q--IREE-----------FKQVHHK-------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 SRGRGRVIE-------------DAEERPH-----------SRYLRRAHS-----------
PLK3_Mmus_PLK2                ------------------------------------------------------------
PLK2_Mmus_PLK2                ------------------------------------------------------------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             ---------------------------P--------------------------------
CDC5_Scer_PLK1                ---------EKSLLLE-----------S-------------------MS-----------
zyg-1_Cele_SAK                ---------------------------S-------------------SR-----------
PLK_Ddis_PLK1                 ---------QQHLQLA--------------------------------GTTSPTKNNNHH
8635_Tthe_SAK                 -----LKNQKSLTSMK--------------------------------L-----------
18358b_Tthe_PLK-Unclassified  ---------Q--------------------------------------------------
18380_Tthe_PLK-Unclassified   ---------Q--------------------------------------------------
21183_Tthe_SAK                ---------QGHTRQR--------------------------------S-----------
22503_Tthe_PLK-Unclassified   ---------KSQLQLA--------------------------------N-----------
5034_Tthe_SAK                 ---------QKEINFA--------------------------------R-----------
8829_Tthe_PLK-Unclassified    ---------QAPMRLT--------------------------------D-----------
SAK_Spur_SAK                  PPVRQRANHSAALQSRSEQAGETLESRPWFSGAALKQKASSSQDLRMTS-----------
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   ---------QQSMQIG--------------------------------T-----------
n808_Tthe_PLK-Unclassified    ----------RIILI---------------------------------T-----------
CC1G_07437_Ccin_PLK1          ----------------EK-------------------------------------EF-QR
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 ---------------------S-D-----RSGTS--NSQSQAKT----------------
PLK3_Hsap_PLK2                -------------------FGR-KKK-SK-------------------------------
PLK2_Hsap_PLK2                -------------------FGG-KKDKAR---------------Y---------------
PLK1_Hsap_PLK1                -------------------NKG-LE-----------------------------------
polo_Dmel_PLK1                -------------------NGI--------------------------------------
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                -------------------LTQ-CRPPCP---------------F---------------
PLK4_Mmus_SAK                 ---------------------S-D-----RASPS--N-QSRAKT----------------
PLK3_Mmus_PLK2                -------------------FGR-KKNKNK-------------------------------
PLK2_Mmus_PLK2                -------------------FGG-KKDKAR---------------Y---------------
PLK1_Mmus_PLK1                -------------------NKG-VE-----------------------------------
plk-2_Cele_PLK1               -------------------DQ--RG-----------------------------------
plk-1_Cele_PLK1               -------------------AR--SQ-----------------------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                ---------------------S-D-----KIQ-------RQKRD----------------
zyg-1_Cele_SAK                ---------------------D-D-----R-----------SRD----------------
PLK_Ddis_PLK1                 YQQYQQQPQQQYNNNYQQSF-S-------PK--------KQINN----------------
8635_Tthe_SAK                 ---------------------D-------LS--------------DCNKEN-QPNLINSS
18358b_Tthe_PLK-Unclassified  ----------------------------------------KSTN----------------
18380_Tthe_PLK-Unclassified   -----------------------------KI--------G-SGS----------------
21183_Tthe_SAK                ---------------------N-------FS------------------------MDSSN
22503_Tthe_PLK-Unclassified   ---------------------N-------GA---------QPYDYNCQNENQTPHISTTQ
5034_Tthe_SAK                 -----------------------------KN------------------------SPVDR
8829_Tthe_PLK-Unclassified    ---------------------S-------AS--------QSTTN----------------
SAK_Spur_SAK                  ---------------------S-D-----RMQPHVSSHTSQTRD----------------
PLK1_Spur_PLK1                -------------------NGQ-DE-----------------------------------
PLK2_Spur_PLK2                -------------------INNDSS-----------------------------------
n1170_Tthe_PLK-Unclassified   -----------------EVFGS-SRKEMTKS--------QTTTN----------------
n808_Tthe_PLK-Unclassified    -----------------LS-----------------------------------------
CC1G_07437_Ccin_PLK1          AVQP-GSPISA-------LLSS-ARQPLL---------------V-GP------------
AqueK200_Aque_PLK1            -------------------N----------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   -------------------NAG-GT-----------------------------------


PLK4_Hsap_SAK                 ----YT-----------MERCHSAEMLSVSKRSG------GGEN-----EERYS------
PLK3_Hsap_PLK2                ------------------------------------------------------------
PLK2_Hsap_PLK2                ------------------------------------------------------------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  ------------------LPYEQTGLFGQAS-----------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ----YS-----------VERCHSVEMLSKPRR----------------------------
PLK3_Mmus_PLK2                ------------------------------------------------------------
PLK2_Mmus_PLK2                ------------------------------------------------------------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                ----YI-----------S------------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ----MN-----------N--------------NNN-----NNNNNNN--NN----NN---
8635_Tthe_SAK                 NNKS--------------------------------------NNTA--------------
18358b_Tthe_PLK-Unclassified  ----YQ-----------V--------------EN---------------KN----S----
18380_Tthe_PLK-Unclassified   ----LA-------------------------------------------ST----QS---
21183_Tthe_SAK                NSKHFQQNKIMNDNLYQI--------------NNINRSNQIQENNVLQNKQ----T----
22503_Tthe_PLK-Unclassified   STKHFQRSN-----------------------------------HFYQTQS----S----
5034_Tthe_SAK                 FDV---------------------------------------------------------
8829_Tthe_PLK-Unclassified    ----IK-----------G--------------KN---------------AS----TS---
SAK_Spur_SAK                  ----YN-----------LTAKPS--------IND------GSMK-------GFDTKTRGM
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   ----MN------KALFQN--------------ENGNKVLDGQKN-----QA----TS---
n808_Tthe_PLK-Unclassified    --------------------------------------FDSKKQ-----S-----DR---
CC1G_07437_Ccin_PLK1          ------------T-------------------AG------GG------------------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ----------------------GSRVLKNIQ-----------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 PTDNNA-------------------------NIF----NFFKEKT-SSSSGSFERPDNNQ
PLK3_Hsap_PLK2                ------------------------------------------------------------
PLK2_Hsap_PLK2                ------------------------------------------------------------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  --------------------------------------T------------GLAEPNW--
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ---------------------------------------------------SL---DENQ
PLK3_Mmus_PLK2                ------------------------------------------------------------
PLK2_Mmus_PLK2                ------------------------------------------------------------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                ------------------------------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ------------------------------------------------------------
8635_Tthe_SAK                 ------------------------------------------------------------
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   ------------------------------------------------------------
21183_Tthe_SAK                ------------------------------------------------------------
22503_Tthe_PLK-Unclassified   ------------------------------------------------------------
5034_Tthe_SAK                 ------------------------------------------------------------
8829_Tthe_PLK-Unclassified    ------------------------------------------------------------
SAK_Spur_SAK                  YQSHEQDIHRSQGHVYHDDAQVKRSGSWKSQEFLGQHGSVLREKSRTETSGHYDRVDD--
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   ------------------------------------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          -----------------------------------------------------GNPGA--
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 ALSNHLCPGKTPFPFADPTPQTETVQQWFGNLQINAHLRKTTEYDSISPNRDFQGHPDLQ
PLK3_Hsap_PLK2                ------------------------------------------------------------
PLK2_Hsap_PLK2                ------------------------------------------------------------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  ----------------------------PGAAK---------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 HSSNHHCLGKTPFPFADQTPQMEMVQQWFGNLQMNAHLGETNEHHTVSPNRDFQDYPDLQ
PLK3_Mmus_PLK2                ------------------------------------------------------------
PLK2_Mmus_PLK2                ------------------------------------------------------------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                ------------------------------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ------------------------------------------------------------
8635_Tthe_SAK                 ------------------------------------------------------------
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   ------------------------------------------------------------
21183_Tthe_SAK                ------------------------------------------------------------
22503_Tthe_PLK-Unclassified   ------------------------------------------------------------
5034_Tthe_SAK                 ------------------------------------------------------------
8829_Tthe_PLK-Unclassified    ------------------------------------------------------------
SAK_Spur_SAK                  -----------------------------------AKHRLFSEADIDS--DRRQ-DLTVR
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   ------------------------------------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          -------VRESPLL-----------------------RKLQAVKE---------------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 KDTSKNAWTDTKVKKNSDASDNAHSV----------------K---Q-----Q--NTMKY
PLK3_Hsap_PLK2                ---------------------------------------------N-HAQ----------
PLK2_Hsap_PLK2                -----------------------------------------IDTHNRVSK----------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                -----------------------------------------TSK--EASG----------
PLK4_Mmus_SAK                 -DTLRNAWTDTRASKNADTSANVHAV----------------K---Q-----L--SAMKY
PLK3_Mmus_PLK2                ---------------------------------------------N-HSE----------
PLK2_Mmus_PLK2                -----------------------------------------NDTHNKVSK----------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             -------------------------V----------------L-----------------
CDC5_Scer_PLK1                --------------------SIKSSI----------------D---K-----L--E----
zyg-1_Cele_SAK                ----------------------GRAL----------------I---R-----S--S----
PLK_Ddis_PLK1                 --------------------NNNNNNNNLKQYNYSNNNINYNNNNNNINNQFA--N----
8635_Tthe_SAK                 ------------------------------------------------------------
18358b_Tthe_PLK-Unclassified  --------------------SPK-KF----------------D-----------------
18380_Tthe_PLK-Unclassified   --------------------QMNMAA----------------T---Q-----S--G----
21183_Tthe_SAK                --------------------KE-NRF----------------Q---S-----K--E----
22503_Tthe_PLK-Unclassified   --------------------ST-ANF----------------K---P-----T--S----
5034_Tthe_SAK                 ----------------------------------------------------ENQQ----
8829_Tthe_PLK-Unclassified    --------------------NLYSKQ----------------T---T-----T--G----
SAK_Spur_SAK                  TDHAKDKCTDKKQSA-------------------------------Q-----S--SVSDH
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   --------------------NPSNQF----------------M---S-----T--A----
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          --------------------SPLGR-RSV-------------TR-T-ANG-Y--------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 MTALHSKPEIIQ--Q-E-------------------------------------------
PLK3_Hsap_PLK2                ---------------------------------ERDEV--SGLVSGL---MRTSVGH--Q
PLK2_Hsap_PLK2                ---------------------------------EDEDI--YKLRHDL---KKTSITQ--Q
PLK1_Hsap_PLK1                -----------------------------------------------------------N
polo_Dmel_PLK1                -----------------------------------------------------------R
SAK_Dmel_SAK                  -------SS---------------------------------------------------
PLK5_Mmus_PLK2                ---------------------------------PGEE------------------GT--E
PLK4_Mmus_SAK                 MSAHHHKPEVMP--Q-E-------------------------------------------
PLK3_Mmus_PLK2                ---------------------------------DQDNV--SCLVSGL---MRTSIGH--P
PLK2_Mmus_PLK2                ---------------------------------EDEDI--YKLRHDL---KKVSITQ--Q
PLK1_Mmus_PLK1                -----------------------------------------------------------N
plk-2_Cele_PLK1               -----------------------------------------------------------P
plk-1_Cele_PLK1               -----------------------------------------------------------R
F55G1.8_Cele_PLK1             -----------P--H-VE-------E----------------------------------
CDC5_Scer_PLK1                -EYHQNRP-FLP--H-SL-------S----------------------------------
zyg-1_Cele_SAK                ---------SQPAHS-GR-------A----------------------------------
PLK_Ddis_PLK1                 ---------L--SPN-SQ-------QKLSEV--ENDDFHYRKLRR-LEKMKEN-------
8635_Tthe_SAK                 ---------I--IEKQK-STK----SN---------------------------------
18358b_Tthe_PLK-Unclassified  ----------------NT-------T----------------------------------
18380_Tthe_PLK-Unclassified   ---------L--QLN-GT-------K----------------------------------
21183_Tthe_SAK                ------------------------------------------------------------
22503_Tthe_PLK-Unclassified   ---------L--SQQHATTNS----N----------------------------------
5034_Tthe_SAK                 ------------------------------------------------------------
8829_Tthe_PLK-Unclassified    ---------A--VPD-AS-------R----------------------------------
SAK_Spur_SAK                  PSVHGMH-AAVP--S-SA-------S----------------------------------
PLK1_Spur_PLK1                -----------------------------------------------------------N
PLK2_Spur_PLK2                -----------------------------------------------------------K
n1170_Tthe_PLK-Unclassified   ---------N--LQQ-NS-------K----------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ------------E-----EDERGKRRMVIETEEEEEDM--RQRRKELE-AQKARIVAQMA
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 -----------------------------------------------------------C
PLK3_Hsap_PLK2                ------------------------------------------------------------
PLK2_Hsap_PLK2                P---S---KHR-T-----------------------------------------------
PLK1_Hsap_PLK1                P---L---PER-P-----------------------------------------------
polo_Dmel_PLK1                P---D---DTR-L-----------------------------------------------
SAK_Dmel_SAK                  -----------------------------------------------------------A
PLK5_Mmus_PLK2                P---D---HME-A-----------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                ------------------------------------------------------------
PLK2_Mmus_PLK2                P---S---KHR-A-----------------------------------------------
PLK1_Mmus_PLK1                P---L---PDR-P-----------------------------------------------
plk-2_Cele_PLK1               H---Q---AGR-S-----------------------------------------------
plk-1_Cele_PLK1               P---L---NGR-A-----------------------------------------------
F55G1.8_Cele_PLK1             P---I-----------------------------S----------------PIYQE---V
CDC5_Scer_PLK1                P---G----G---T--------------------K----------------QKYKE---V
zyg-1_Cele_SAK                P---L-----------------------------S----------------NRPIH---D
PLK_Ddis_PLK1                 D---L---KT---Q--------------------L----------------LIKQQYT-N
8635_Tthe_SAK                 T---Y---KE---QQNIQ-SN-QQNSLGMSNIFLTTARSINLADNSIIMSTLQDNQLNNT
18358b_Tthe_PLK-Unclassified  P---I---NGN-GF--------------------T----------------RFATQ-T-S
18380_Tthe_PLK-Unclassified   D---L---NG---N----------------------------------------------
21183_Tthe_SAK                ---------------QLLVNENKEN--------IH----------------SN--ILNSI
22503_Tthe_PLK-Unclassified   N---L---QD---TNSTN-TNENNT--------ISS-------------NNPNN-NEINI
5034_Tthe_SAK                 ---------------NN-MNKQKDD--------A--------------------------
8829_Tthe_PLK-Unclassified    P---L---GG---T--------------------T----------------SNWNQ---V
SAK_Spur_SAK                  C---G----G---L--------------------S----------------SKQDG---A
PLK1_Spur_PLK1                V---P---PGR-E-----------------------------------------------
PLK2_Spur_PLK2                Q---G---SGT-T-----------------------------------------------
n1170_Tthe_PLK-Unclassified   N---L-----------------------------N----------------SNFNQ-N-D
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          P---V---K---------------------------------------------------
AqueK200_Aque_PLK1            P---M---TDA-M-----------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   DGRFIAATPQAIG-----------------------------------------------


PLK4_Hsap_SAK                 V-----------------------------------------------------------
PLK3_Hsap_PLK2                ---DARP-----------------------------------------------------
PLK2_Hsap_PLK2                ---DEEL-----------------------------------------------------
PLK1_Hsap_PLK1                ---REK------------------------------------------------------
polo_Dmel_PLK1                ---EST------------------------------------------------------
SAK_Dmel_SAK                  FC--ME------------------------------------------------------
PLK5_Mmus_PLK2                ---GNEE-----------------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                ---DVRP-----------------------------------------------------
PLK2_Mmus_PLK2                ---DEEP-----------------------------------------------------
PLK1_Mmus_PLK1                ---REK------------------------------------------------------
plk-2_Cele_PLK1               ---GLS------------------------------------------------------
plk-1_Cele_PLK1               ---GLS------------------------------------------------------
F55G1.8_Cele_PLK1             AN--EE------------------------------------------------------
CDC5_Scer_PLK1                VD--IEA-----------------------------------------------------
zyg-1_Cele_SAK                RM--PS------------------------------------------------------
PLK_Ddis_PLK1                 MNENQQQ-----------------------------------------------------
8635_Tthe_SAK                 NN--K-KENTKPTQK--------LQYYLQQNSNTSQQL-KQ----------SSILNNQGQ
18358b_Tthe_PLK-Unclassified  YN--PQN-----------------------------------------------------
18380_Tthe_PLK-Unclassified   ------------------------------------------------------------
21183_Tthe_SAK                NN--Q-QKLFQQQQKLNPIPLQKSYSYNQKNE-----Q-KQ----------DQILH-QTL
22503_Tthe_PLK-Unclassified   AN--QENDNY-QLLRM---------------------R-SQENIQFSRQFQNYF------
5034_Tthe_SAK                 ---------------SHTVKVKEIHSHNQQLN-----IRKQ----------S-PTN-QIL
8829_Tthe_PLK-Unclassified    SS--QKD-----------------------------------------------------
SAK_Spur_SAK                  LH--KDS-----------------------------------------------------
PLK1_Spur_PLK1                ---Q-S------------------------------------------------------
PLK2_Spur_PLK2                --SQNS------------------------------------------------------
n1170_Tthe_PLK-Unclassified   FN--QTD-----------------------------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          --E---------------------------------------------EVE---------
AqueK200_Aque_PLK1            ---DTA------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ---GTE------------------------------------------------------


PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                ------------------------------------------------------------
PLK2_Hsap_PLK2                ------------------------------------------------------------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                ------------------------------------------------------------
PLK2_Mmus_PLK2                ------------------------------------------------------------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                ------------------------------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ------------------------------------------------------------
8635_Tthe_SAK                 ASG-------YNNSRN--RFDLSCNNVINQNKSQQSLLQYNGYKSQSVIPQQQQAFSQNS
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   ------------------------------------------------------------
21183_Tthe_SAK                AQG-------LKKEVSEQS--------IDN-----------NRNKQII--QEIQNISQNS
22503_Tthe_PLK-Unclassified   -QG-------KKE--------------------------------NSL--QKYPSSQQFT
5034_Tthe_SAK                 NYDKDKIAIPERKSLTQQS--------QAI-----------NQND---------------
8829_Tthe_PLK-Unclassified    ------------------------------------------------------------
SAK_Spur_SAK                  ------------------------------------------------------------
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   ------------------------------------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ----------RE----------------------EREDEDDEEEDEDGM-----------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                -----------------------------------EAPAAS-GP-----AP---------
PLK2_Hsap_PLK2                -----------------------------------QPPTTTVAR-----SG---------
PLK1_Hsap_PLK1                -----------------------------------EEP----------------------
polo_Dmel_PLK1                -----------------------------------FLK----------------------
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                -----------------------------------RDPLCTEG-----------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                -----------------------------------EAPVVS-GQ-----AP---------
PLK2_Mmus_PLK2                -----------------------------------QPPPTTVAR-----SG---------
PLK1_Mmus_PLK1                -----------------------------------EEP----------------------
plk-2_Cele_PLK1               -----------------------------------AIP----------------------
plk-1_Cele_PLK1               -----------------------------------ALP----------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                -----------------------------------QRRLN--------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 -----------------------------------QQQQQ--------------------
8635_Tthe_SAK                 Q-------------------------------QISNKNQP--------------------
18358b_Tthe_PLK-Unclassified  -----------------------------------VKS-Q--------------------
18380_Tthe_PLK-Unclassified   -----------------------------------MRS-Q--------------------
21183_Tthe_SAK                Y--------------------------YN-P-QISQSNKQ--------------------
22503_Tthe_PLK-Unclassified   ---------------------------GN-P-IS--SN----------------------
5034_Tthe_SAK                 VFKSPKLTSNQQEIKQTFINNIEKIKSNQ-P-PVPQ-NQQ--------------------
8829_Tthe_PLK-Unclassified    -----------------------------------QRPQT--------------------
SAK_Spur_SAK                  ------------------------------------------------------------
PLK1_Spur_PLK1                -----------------------------------GKP----------------------
PLK2_Spur_PLK2                -----------------------------------GKP------------SSQPKLRTRI
n1170_Tthe_PLK-Unclassified   -----------------------------------QRPTT--------------------
n808_Tthe_PLK-Unclassified    -------------------------------------QS---------------------
CC1G_07437_Ccin_PLK1          -------------------GGRRR----APPPPPP-----VFKREREHQK----------
AqueK200_Aque_PLK1            ------------------------------------GG----------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   -----------------------------------HIPTP--------------------


PLK4_Hsap_SAK                 -------------------------------------------------------FGSDP
PLK3_Hsap_PLK2                ----------------------------------------------V--S-LVETA----
PLK2_Hsap_PLK2                ----------------------------------------------T--P-AVENK----
PLK1_Hsap_PLK1                ---------------------------------------------------VV-R-----
polo_Dmel_PLK1                ----------------------------------------------A--N-LHD------
SAK_Dmel_SAK                  -------------------------------------------------------AGNVP
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 -------------------------------------------------------PGLHP
PLK3_Mmus_PLK2                ----------------------------------------------A--S-LVETA----
PLK2_Mmus_PLK2                ----------------------------------------------T--S-AVENK----
PLK1_Mmus_PLK1                ---------------------------------------------------VV-R-----
plk-2_Cele_PLK1               ----------------------------------------------A--H-LVSRN----
plk-1_Cele_PLK1               ----------------------------------------------Q--H-IVSNN----
F55G1.8_Cele_PLK1             ------------------------------------------------------TSEI--
CDC5_Scer_PLK1                ----------------------------------------------D--L--AREARI-R
zyg-1_Cele_SAK                ------------------------------------------------------TSSRGF
PLK_Ddis_PLK1                 ----------------------------------------------Q--Q-QQQ-----Q
8635_Tthe_SAK                 ----------------------------------------------Q--Q--QN------
18358b_Tthe_PLK-Unclassified  ----------------------------------------------Q--Q--MG-----L
18380_Tthe_PLK-Unclassified   ----------------------------------------------S-------------
21183_Tthe_SAK                ----------------------------------------------Q--Q--QQ-----I
22503_Tthe_PLK-Unclassified   -------------------------------------------------Q--NI-----L
5034_Tthe_SAK                 ----------------------------------------------QQNN--SA-----I
8829_Tthe_PLK-Unclassified    ----------------------------------------------Q--Q--FQ-----K
SAK_Spur_SAK                  ------------------------------------------------------KAGERS
PLK1_Spur_PLK1                ---------------------------------------------------HR-KH----
PLK2_Spur_PLK2                TGS------------------------------------RPMTPVTS--A-IKTAM----
n1170_Tthe_PLK-Unclassified   ----------------------------------------------S--K--VQ-----T
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          -GSSAGSNRYAGEDVENVPPRLGGAQQARRDVAKGKAVERPRAREK--------------
AqueK200_Aque_PLK1            ---------------------------------------------------VL-KP----
AqueK201_Aque_SAK             --------------------------------------------------------LEAP
GK066_Glam_PLK-Unclassified   ----------------------------------------------G--TANFYKP----


PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                ------------------------------------------------------------
PLK2_Hsap_PLK2                ------------------------------------------------------------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                ------------------------------------------------------------
PLK2_Mmus_PLK2                ------------------------------------------------------------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                ------------------------------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ------------------------------------------------------------
8635_Tthe_SAK                 ------------------------------------------------------------
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   ------------------------------------------------------------
21183_Tthe_SAK                D-----------------------------------------------------------
22503_Tthe_PLK-Unclassified   N-----------------------------------------------------------
5034_Tthe_SAK                 TTYGGQEKRGVKSIVYNNSNNQNNINTNQNSNQYNIQNSITNNQINPTNNYKTVNSSNIN
8829_Tthe_PLK-Unclassified    ------------------------------------------------------------
SAK_Spur_SAK                  ------------------------------------------------------------
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   ------------------------------------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ----------------------ENVP----------------------------------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 ----------------------------------------------LSEQ-S--KTRG-M
PLK3_Hsap_PLK2                ----------------------------------------------P--E-D-----S-S
PLK2_Hsap_PLK2                ----------------------------------------------QQIG-D--AIRM-I
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------A--I-T
SAK_Dmel_SAK                  ----------------------------------------------NSKQ-A--SLKE--
PLK5_Mmus_PLK2                -----------------------------------------------R-------IH---
PLK4_Mmus_SAK                 ----------------------------------------------HSEQ-S--KNRS-M
PLK3_Mmus_PLK2                ----------------------------------------------A--E-D-----S-S
PLK2_Mmus_PLK2                ----------------------------------------------QQIG-D--AIRM-I
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               -------------------------------------------------S-ERQ------
plk-1_Cele_PLK1               -------------------------------------------------A-DRER--A-Q
F55G1.8_Cele_PLK1             -------------------------------------------------R-R--FVKT-E
CDC5_Scer_PLK1                ----------------------------------------------RAQQ-A--VLRK-E
zyg-1_Cele_SAK                ----------------------------------------------DSER-G--RERD-R
PLK_Ddis_PLK1                 ----------------------------------------------QQQQ-Q--RVNN-N
8635_Tthe_SAK                 ------------------------------------------TKELTPKQFN--------
18358b_Tthe_PLK-Unclassified  ----------------------------------------------KERK-D--YINT-Y
18380_Tthe_PLK-Unclassified   ---------------------------------------------------------N-K
21183_Tthe_SAK                ------------------------------------------TIQQKPQS-K--TI----
22503_Tthe_PLK-Unclassified   -------------------------------------------QHQSPP--K--NLN---
5034_Tthe_SAK                 NNYYSNTSQSQQFINGINHQHDIHSRTAANSNHDKYIKNTNNIRNNSPVN----------
8829_Tthe_PLK-Unclassified    ----------------------------------------------SDFK-T--SMST-K
SAK_Spur_SAK                  ----------------------------------------------SHRR-S--KSKS-H
PLK1_Spur_PLK1                -------------------------------------------------S-D--R--K-E
PLK2_Spur_PLK2                -------------------------------------------------V-N--V--IEK
n1170_Tthe_PLK-Unclassified   ----------------------------------------------GT-Q-Q--GLYN-K
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ------------------------------------------------------------
AqueK200_Aque_PLK1            -------------------------------------------------G-G--G--A-T
AqueK201_Aque_SAK             ----------------------------------------------ASVD-S--------
GK066_Glam_PLK-Unclassified   -------------------------------------------------Q-N--A-----


PLK4_Hsap_SAK                 EPP---W--------------------------GYQNRTLRSITSPLVAHRLKPIRQKTK
PLK3_Hsap_PLK2                PRGTLAS-----------------------------------------------------
PLK2_Hsap_PLK2                VRGTLGS-----------------------------------------------------
PLK1_Hsap_PLK1                ------E-----------------------------------------------------
polo_Dmel_PLK1                ASAQVCR-----------------------------------------------------
SAK_Dmel_SAK                  ---------------------------------------DRISVPPLNTKRLLPTRYKTK
PLK5_Mmus_PLK2                -LLTLGT-----------------------------------------------------
PLK4_Mmus_SAK                 EST---L--------------------------GYQKPTLRSITSPLIAHRLKPIRQKTK
PLK3_Mmus_PLK2                PRGTLAS-----------------------------------------------------
PLK2_Mmus_PLK2                VRGTLGS-----------------------------------------------------
PLK1_Mmus_PLK1                ------E-----------------------------------------------------
plk-2_Cele_PLK1               QTHRMEA-----------------------------------------------------
plk-1_Cele_PLK1               QQAAEAT-----------------------------------------------------
F55G1.8_Cele_PLK1             QAS---------------------------------------------------------
CDC5_Scer_PLK1                LIA---T-----------------------------------------------------
zyg-1_Cele_SAK                DSG---R-----------------------------------------------------
PLK_Ddis_PLK1                 INN---N--------------------------G--------------------------
8635_Tthe_SAK                 ------------------------------------------------------------
18358b_Tthe_PLK-Unclassified  RTGGAQT--------------------------S--------------------------
18380_Tthe_PLK-Unclassified   NLG---------------------------------------------------------
21183_Tthe_SAK                ---------------------------------L--------------------------
22503_Tthe_PLK-Unclassified   -TA---A--------------------------G--------------------------
5034_Tthe_SAK                 ---------------------------------N--------------------------
8829_Tthe_PLK-Unclassified    NMG---S--------------------------G--------------------------
SAK_Spur_SAK                  DLD---KGSEWTHRHTRKHEKREGGGGGGKGEGGAGVQSLAHLTPPLNATRLRPIRQRTR
PLK1_Spur_PLK1                NGGGKPK-----------------------------------------------------
PLK2_Spur_PLK2                RSAAVTM-----------------------------------------------------
n1170_Tthe_PLK-Unclassified   Q-Q---T--------------------------G--------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ----VSS-----------------------------------------------------
AqueK200_Aque_PLK1            ATHFVEK-----------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ---ILTT-----------------------------------------------------


PLK4_Hsap_SAK                 KAV---VSILD-SE--------------E--VCVELVKE--YA-SQEYVKE---------
PLK3_Hsap_PLK2                -------------S--GD--GFEEGLTV-------------AT-VVESALCAL-------
PLK2_Hsap_PLK2                ---------CS-SS--SE--CLE-DSTM-------------GS-VADTVARVL-------
PLK1_Hsap_PLK1                ---------TG-EV--VD--C-----------------------HLSDMLQQL-------
polo_Dmel_PLK1                ---------HS-ED--YR--S-----------------------DIESLYQQL-------
SAK_Dmel_SAK                  NAI---MSILR-NG--------------E--VVLEFLKFRPTY-NEDRIND---------
PLK5_Mmus_PLK2                ---------PR-TG--LA--GP-KG-SL-------------AL-QLEVATRKL-------
PLK4_Mmus_SAK                 KAV---VSILD-SE--------------E--VCVELLRE--CA-SEGYVKE---------
PLK3_Mmus_PLK2                -------------S--GD--GFEEGLTV-------------AT-VVESALCAL-------
PLK2_Mmus_PLK2                ---------CS-SS--SE--CLE-DSTM-------------GS-VADTVARVL-------
PLK1_Mmus_PLK1                ---------TN-EA--IE--C-----------------------HLSDLLQQL-------
plk-2_Cele_PLK1               ---------YR-QP--TD--C-----------------------YLSNLLAQV-------
plk-1_Cele_PLK1               ---------FR-EP--ED--A-----------------------YLSQLFHQV-------
F55G1.8_Cele_PLK1             ------S--FG-DE--------------------------LSQ-LQAQISH---------
CDC5_Scer_PLK1                --S---TNVIK-SE--------------I--S--------LRI-LASECHL---------
zyg-1_Cele_SAK                --G---T--VP-PS--------------------------REDRNRSQL-----------
PLK_Ddis_PLK1                 --N-----TVT-VT--T---GN------N-TV--------NVQ--IKELETK-I------
8635_Tthe_SAK                 --------PYLSQ-----------------------------------------------
18358b_Tthe_PLK-Unclassified  --S---SSGLCNSQ--Y---GQK-NFDTNNVN--------NQK--IDNFLQTNK------
18380_Tthe_PLK-Unclassified   --S----------------------------N--------QMD--QANLLKM-Q------
21183_Tthe_SAK                --NTFLNK---ATK--SNSL--------------------HQS--S----ST-TPSSNQQ
22503_Tthe_PLK-Unclassified   --YSSVEKPSYSQS--SQTKV-------P--T--------LTS--SQKFD--------IK
5034_Tthe_SAK                 --NSYIER--NQSPNTQNNH--------------------MSS--SSVLNNG-QQ-QSQH
8829_Tthe_PLK-Unclassified    --S---QNPLFNQT--N---A-------P--G--------LAT--AQSLNTF-T------
SAK_Spur_SAK                  NAV---VSIML-GG--------------E--VCLEFLKT--KD-GQDRVVE---------
PLK1_Spur_PLK1                ---------VY-QP--KE--D-----------------------HLASLKVHL-------
PLK2_Spur_PLK2                ---------VK-SA--SI--C-----------------------SMDKVYEML-------
n1170_Tthe_PLK-Unclassified   --T---QDPNNKQQ--Q---G-------N--K--------YQS--VQNLMSM-N------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ------SNP-----------AP-AAPKLN---------------GFDAAAQIL-------
AqueK200_Aque_PLK1            ---------IQ-GS--ED--W-----------------------HLNSLLLQL-------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ----------K-SA--AG--I-----------------------SRASTAMAM-------


PLK4_Hsap_SAK                 -----------------VLQ--------------ISSDGNTITIY---------------
PLK3_Hsap_PLK2                -------------------R--------------N------CIAF---------------
PLK2_Hsap_PLK2                -------------------R--------------G------CLEN---------------
PLK1_Hsap_PLK1                -------------------H--------------S------VNAS---------------
polo_Dmel_PLK1                -------------------T--------------N------LING---------------
SAK_Dmel_SAK                  -----------------ICR--------------ISDDGQRIIIY---------------
PLK5_Mmus_PLK2                -------------------F--------------L------CLDA---------------
PLK4_Mmus_SAK                 -----------------VLQ--------------ISSDGTMITVY---------------
PLK3_Mmus_PLK2                -------------------R--------------N------CVAF---------------
PLK2_Mmus_PLK2                -------------------R--------------G------CLEN---------------
PLK1_Mmus_PLK1                -------------------T--------------S------VNAS---------------
plk-2_Cele_PLK1               -------------------N--------------D------LLAT---------------
plk-1_Cele_PLK1               -------------------A--------------V------LLEQ---------------
F55G1.8_Cele_PLK1             -----------------ILQ--------------N------VVAS---------------
CDC5_Scer_PLK1                -----------------TLN--------------G------IVEA---------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 -----------------ANNHISDSPPVS----SN------NNYP---------------
8635_Tthe_SAK                 ------------------------------------------------------------
18358b_Tthe_PLK-Unclassified  -----------------NTY--------G----LN------GSVA---------------
18380_Tthe_PLK-Unclassified   -----------------SMQ--------------T------LKHG---------------
21183_Tthe_SAK                NI---------------NTNNFFQS-QK--------------------------------
22503_Tthe_PLK-Unclassified   KY---------------NTIHISDTNQNQ--NHNK------ANNPY--------------
5034_Tthe_SAK                 KNNSYSISQSKVIPLPKKVQTSFLQNLNSLTDVDR------FSPPHNNTNSTNTTTNNYV
8829_Tthe_PLK-Unclassified    -----------------KTK--------------N------NFNS---------------
SAK_Spur_SAK                  -----------------VLR--------------ISQDGMQVTIY---------------
PLK1_Spur_PLK1                -------------------T--------------S------VVAA---------------
PLK2_Spur_PLK2                -------------------N--------------T------CLEH---------------
n1170_Tthe_PLK-Unclassified   -----------------KTD--------------G------FQNP---------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          -------------------T--------------M------AFDA---------------
AqueK200_Aque_PLK1            -------------------S--------------S------CLTS---------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   -------------------Q--------------N------VGSA---------------


PLK4_Hsap_SAK                 ----------------------------------------------YP----NG------
PLK3_Hsap_PLK2                ----------------------------------------------MPP--A--------
PLK2_Hsap_PLK2                ----------------------------------------------MPE--A--------
PLK1_Hsap_PLK1                ----------------------------------------------KPS--ERGL-----
polo_Dmel_PLK1                ----------------------------------------------KPR--ILQG-----
SAK_Dmel_SAK                  ----------------------------------------------QP----DP------
PLK5_Mmus_PLK2                ----------------------------------------------GPM--A--------
PLK4_Mmus_SAK                 ----------------------------------------------YP----ND------
PLK3_Mmus_PLK2                ----------------------------------------------MPP--A--------
PLK2_Mmus_PLK2                ----------------------------------------------MPE--A--------
PLK1_Mmus_PLK1                ----------------------------------------------KPS--ERGL-----
plk-2_Cele_PLK1               ----------------------------------------------PTADIDDAE-----
plk-1_Cele_PLK1               ----------------------------------------------RIPGLEEEE-----
F55G1.8_Cele_PLK1             ----------------------------------------------KN----KSS-----
CDC5_Scer_PLK1                ----------------------------------------------EA----QYK-----
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ----------------------------------------------QQI--QKQQ-----
8635_Tthe_SAK                 -NS---------------------------------------------------------
18358b_Tthe_PLK-Unclassified  ----------------------------------------------KE----QCF-----
18380_Tthe_PLK-Unclassified   ----------------------------------------------QF----NSD-----
21183_Tthe_SAK                -------SYKNP------------------I---------VQI----L----NGFPNDSK
22503_Tthe_PLK-Unclassified   --------YNL----------------------------------PAQ----SGQ-----
5034_Tthe_SAK                 NIQSEINNFPQPQTVSHNRTKNQVSFENKPIQAQVQNQTTQKVMQSSD----QGF-----
8829_Tthe_PLK-Unclassified    ----------------------------------------------TQ----KGF-----
SAK_Spur_SAK                  ----------------------------------------------QP----NG------
PLK1_Spur_PLK1                ----------------------------------------------KPS--EKAD-----
PLK2_Spur_PLK2                ----------------------------------------------MPK--E--D-----
n1170_Tthe_PLK-Unclassified   ----------------------------------------------QN----QQQ-----
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ----------------------------------------------RAA--GR-V-----
AqueK200_Aque_PLK1            ----------------------------------------------CPS--TKNP-----
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ----------------------------------------------QGV--V-NK-----


PLK4_Hsap_SAK                 ---------------------GRGF----PLADRPPSPT--DNISRYSFDNLPEKYWRKY
PLK3_Hsap_PLK2                ----------------------E-Q----NP-----------------------------
PLK2_Hsap_PLK2                ----------------------D-C----IP-----------------------------
PLK1_Hsap_PLK1                ---------------------VR-Q----EE-----------------------------
polo_Dmel_PLK1                ---------------------NL-G----DE-----------------------------
SAK_Dmel_SAK                  ---------------------GRGL----PVREQPPDLQIPSGDCVYNYDNLPSKHWKKY
PLK5_Mmus_PLK2                ----------------------G-Q----DP-----------------------------
PLK4_Mmus_SAK                 ---------------------GRGF----PLADRPPLPT--DNISRYSFDNLPEKYWRKY
PLK3_Mmus_PLK2                ----------------------E-Q----NP-----------------------------
PLK2_Mmus_PLK2                ----------------------D-C----IP-----------------------------
PLK1_Mmus_PLK1                ---------------------VR-Q----EE-----------------------------
plk-2_Cele_PLK1               ---------------------AA-L----DS-----------------------------
plk-1_Cele_PLK1               ---------------------AA-L----DG-----------------------------
F55G1.8_Cele_PLK1             ---------------------T-RF----GL-----------------------------
CDC5_Scer_PLK1                ---------------------MGGL----PK-----------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ---------------------PNFN----NE-----------------------------
8635_Tthe_SAK                 ------------------------------------------------------------
18358b_Tthe_PLK-Unclassified  ---------------------QK-S----SS-----------------------------
18380_Tthe_PLK-Unclassified   ---------------------LNSE----NI-----------------------------
21183_Tthe_SAK                IQQNQAINHQKNKSLDISGIIPPQPPRPRDE-----------------------------
22503_Tthe_PLK-Unclassified   ---------------------QNSNQSPLEQ-----------------------------
5034_Tthe_SAK                 ---------------------YKKNNNPPQS-----------------------------
8829_Tthe_PLK-Unclassified    ---------------------MQ-T----GT-----------------------------
SAK_Spur_SAK                  ---------------------GKGF----PIMEHPPSPPQDSGITKHSYHDLPSKYWKKY
PLK1_Spur_PLK1                ---------------------IR-L----DE-----------------------------
PLK2_Spur_PLK2                ---------------------HR-T----TP-----------------------------
n1170_Tthe_PLK-Unclassified   ---------------------LNGE----EN-----------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ---------------------FR-S----PL-----------------------------
AqueK200_Aque_PLK1            ---------------------AH-Y----DE-----------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ---------------------YG-I----NE-----------------------------


PLK4_Hsap_SAK                 QYASRFVQLVRSKSPKITYFTRYAKCILMENSPGAD------------------------
PLK3_Hsap_PLK2                ------------------------------------------------------------
PLK2_Hsap_PLK2                ------------------------------------------------------------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  IYGARFVGLVKSKTPKVTYFSTLGKCQLMETM--TD------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 QYASRFIQLVRSKTPKITYFTRYAKCILMENSPGAD------------------------
PLK3_Mmus_PLK2                ------------------------------------------------------------
PLK2_Mmus_PLK2                ------------------------------------------------------------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                ------------------------------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ------------------------------------------------------------
8635_Tthe_SAK                 ------------------------------------------------------------
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   ------------------------------------------------------------
21183_Tthe_SAK                ------------------------------------------------------------
22503_Tthe_PLK-Unclassified   ------------------------------------------------------------
5034_Tthe_SAK                 ------------------------------------------------------------
8829_Tthe_PLK-Unclassified    ------------------------------------------------------------
SAK_Spur_SAK                  QYASRFIQLVRSKTPKVTLYTPHAKCMLMENGPTADCEACFYDGTKIHATSVELEVTESN
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   ------------------------------------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ------------------------------------------------------------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                ------------------------------------------------------------
PLK2_Hsap_PLK2                ------------------------------------------------------------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                ------------------------------------------------------------
PLK2_Mmus_PLK2                ------------------------------------------------------------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                ------------------------------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ------------------------------------------------------------
8635_Tthe_SAK                 ------------------------------------------------------------
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   ------------------------------------------------------------
21183_Tthe_SAK                ------------------------------------------------------------
22503_Tthe_PLK-Unclassified   ------------------------------------------------------------
5034_Tthe_SAK                 ------------------------------------------------------------
8829_Tthe_PLK-Unclassified    ------------------------------------------------------------
SAK_Spur_SAK                  GQTCKLPADQNNDQIPSHLKPIISSFYTWRQHCVDVESAIASLESRHGYGPFFPLILSRK
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   ------------------------------------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ------------------------------------------------------------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ---------------------------GNVTLATN-------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                ------------------------------------------------------------
PLK2_Hsap_PLK2                ------------------------------------------------------------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                ------------------------------------------------------------
PLK2_Mmus_PLK2                ------------------------------------------------------------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                ------------------------------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ------------------------------------------------------------
8635_Tthe_SAK                 ------------------------------------------------------------
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   ------------------------------------------------------------
21183_Tthe_SAK                ------------------------------------------------------------
22503_Tthe_PLK-Unclassified   ------------------------------------------------------------
5034_Tthe_SAK                 ------------------------------------------------------------
8829_Tthe_PLK-Unclassified    ------------------------------------------------------------
SAK_Spur_SAK                  PLQESYQQGNKLPASTNIRTSAVTSHTTPATTTTTSTTTVPPSTTPHPSGPTQACPQGSV
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   ------------------------------------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ------------------------------------------------------------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                ------------------------------------------------------AP----
PLK2_Hsap_PLK2                ------------------------------------------------------KE----
PLK1_Hsap_PLK1                ------------------------------------------------------AE----
polo_Dmel_PLK1                ------------------------------------------------------NT----
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                ------------------------------------------------------AP----
PLK2_Mmus_PLK2                ------------------------------------------------------KE----
PLK1_Mmus_PLK1                ------------------------------------------------------AE----
plk-2_Cele_PLK1               ------------------------------------------------------YQ----
plk-1_Cele_PLK1               ------------------------------------------------------YQ----
F55G1.8_Cele_PLK1             ------------------------------------------------------NH----
CDC5_Scer_PLK1                ------------------------------------------------------SR----
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ------------------------------------------------------FY----
8635_Tthe_SAK                 ------------------------------------------------------------
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------LN----
18380_Tthe_PLK-Unclassified   ------------------------------------------------------LV----
21183_Tthe_SAK                ------------------------------------------------------QKNQLS
22503_Tthe_PLK-Unclassified   ------------------------------------------------------IN----
5034_Tthe_SAK                 ------------------------------------------------------VQTNLQ
8829_Tthe_PLK-Unclassified    ------------------------------------------------------QN----
SAK_Spur_SAK                  TSPSVMAAPTASVCSFDGTICSVARSVQGKDRTRHRKIDKGGSSKEASKVTSQASS----
PLK1_Spur_PLK1                ------------------------------------------------------AE----
PLK2_Spur_PLK2                ------------------------------------------------------KY----
n1170_Tthe_PLK-Unclassified   ------------------------------------------------------NQ----
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ------------------------------------------------------GD----
AqueK200_Aque_PLK1            ------------------------------------------------------AE----
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------AE----


PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                ---LAQ------------------------------------------------------
PLK2_Hsap_PLK2                ----QL------------------------------------------------------
PLK1_Hsap_PLK1                ---DPA------------------------------------------------------
polo_Dmel_PLK1                ---DPA------------------------------------------------------
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                ---PGE------------------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                ---LAQ------------------------------------------------------
PLK2_Mmus_PLK2                ----QL------------------------------------------------------
PLK1_Mmus_PLK1                ---DPA------------------------------------------------------
plk-2_Cele_PLK1               ---SPE------------------------------------------------------
plk-1_Cele_PLK1               ---SPE------------------------------------------------------
F55G1.8_Cele_PLK1             ---SPE------------------------------------------------------
CDC5_Scer_PLK1                ---LPK------------------------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ---LGM------------------------------------------------------
8635_Tthe_SAK                 ------------------------------------------------------------
18358b_Tthe_PLK-Unclassified  ---PQS------------------------------------------------------
18380_Tthe_PLK-Unclassified   ---NTP------------------------------------------------------
21183_Tthe_SAK                ----------------------FKTIDQENI-----------------------------
22503_Tthe_PLK-Unclassified   ---LLT------------------------------------------------------
5034_Tthe_SAK                 RNQSPQLHVGNKNTSDNLNYYLTKKDHPQCVEDQADKYEEIIHQRKNENKIINRENNIKR
8829_Tthe_PLK-Unclassified    ---FGK------------------------------------------------------
SAK_Spur_SAK                  ---HPE------------------------------------------------------
PLK1_Spur_PLK1                ---DPA------------------------------------------------------
PLK2_Spur_PLK2                ---KPN------------------------------------------------------
n1170_Tthe_PLK-Unclassified   ---IDG------------------------------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ---QPL------------------------------------------------------
AqueK200_Aque_PLK1            ---DPA------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ---YPQ------------------------------------------------------


PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                --PEPLV-WV-SKWV----DYSNKFGFG----------YQLSSR----------------
PLK2_Hsap_PLK2                --STSFQ-WV-TKWV----DYSNKYGFG----------YQLSDH----------------
PLK1_Hsap_PLK1                --CIPIF-WV-SKWV----DYSDKYGLG----------YQLCDN----------------
polo_Dmel_PLK1                --AQPLF-WI-SKWV----DYSDKYGFG----------YQLCDE----------------
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                --QRPVL-WA-PKWV----DYSLKYGFG----------YQLSDG----------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                --PEPLV-WV-SKWV----DYSNKFGFG----------YQLSSR----------------
PLK2_Mmus_PLK2                --STSFQ-WV-TKWV----DYSNKYGFG----------YQLSDH----------------
PLK1_Mmus_PLK1                --CIPIF-WV-SKWV----DYSDKYGLG----------YQLCDN----------------
plk-2_Cele_PLK1               --ALPVF-WI-SKWV----DYSDKYGIG----------YQLCDN----------------
plk-1_Cele_PLK1               --CLPVF-WI-SKWV----DYSDKYGIG----------YQLCDN----------------
F55G1.8_Cele_PLK1             --ATPIF-WV-SQWV----HFPN-HGIG----------YRLCEN----------------
CDC5_Scer_PLK1                --IKHPM-IV-TKWV----DYSNKHGFS----------YQLSTE----------------
zyg-1_Cele_SAK                -------------WP----IRMD-RLEG----------QRVCTA----------------
PLK_Ddis_PLK1                 --PNNLV-YI-SQYA----DFTNKYGLA----------YVLSNS----------------
8635_Tthe_SAK                 ---------E-KTQQ----DYSNNAFKS----------YRSTSSLHQNISIANTSQTYRN
18358b_Tthe_PLK-Unclassified  --EGPDI-WV-SKWV----DYSSKYGLG----------YLLNNG----------------
18380_Tthe_PLK-Unclassified   --PASEI-WV-TQWV----DYSNKYGLG----------YALNNG----------------
21183_Tthe_SAK                -------QKK-QISI----DQSNQNEFVTTPSGNNKMFSQSSNN----------------
22503_Tthe_PLK-Unclassified   --QKQNI-YL-FDYI----DCSSKFGLA----------YYLNNG----------------
5034_Tthe_SAK                 ISSEQNISRVSTEYKNGSNDFNTQNKLN----------NQYNNN----------------
8829_Tthe_PLK-Unclassified    --PVQPV-WV-TQWV----DYSAKYGLG----------YLLSNG----------------
SAK_Spur_SAK                  --G--KD-GV-LKSV-----FVPNIGWA----------SQMSSG----------------
PLK1_Spur_PLK1                --AAPIL-WV-SKWV----DYSDKYGLG----------YQLCDG----------------
PLK2_Spur_PLK2                --PSEVV-WV-IKWV----DYSNKYGFG----------YQLSNK----------------
n1170_Tthe_PLK-Unclassified   --SKNNL-WV-VQYV----DYSSKYGLG----------YLLSNQ----------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          --PEERV-FI-VSWV----DYCNKYGMG----------HF--------------------
AqueK200_Aque_PLK1            --SMPVF-WI-CKWV----DYTDKYGLG----------YQLCDN----------------
AqueK201_Aque_SAK             --------------------YSGPTS-R----------YSTRRG----------------
GK066_Glam_PLK-Unclassified   --IDPPC-YI-MSWV----DYSNRYGFA----------YQISNG----------------


PLK4_Hsap_SAK                 ------------F-EV--------------------------------------------
PLK3_Hsap_PLK2                -----------RV-AV--------------------------------------------
PLK2_Hsap_PLK2                -----------TV-GV--------------------------------------------
PLK1_Hsap_PLK1                -----------SV-GV--------------------------------------------
polo_Dmel_PLK1                -----------GI-GV--------------------------------------------
SAK_Dmel_SAK                  ------------F-EI--------------------------------------------
PLK5_Mmus_PLK2                -----------GS-GV--------------------------------------------
PLK4_Mmus_SAK                 ------------F-EV--------------------------------------------
PLK3_Mmus_PLK2                -----------RV-AV--------------------------------------------
PLK2_Mmus_PLK2                -----------TV-GV--------------------------------------------
PLK1_Mmus_PLK1                -----------SV-GV--------------------------------------------
plk-2_Cele_PLK1               -----------SV-GV--------------------------------------------
plk-1_Cele_PLK1               -----------SV-GV--------------------------------------------
F55G1.8_Cele_PLK1             -----------SS-GM--------------------------------------------
CDC5_Scer_PLK1                -----------DI-GV--------------------------------------------
zyg-1_Cele_SAK                -----------GG-RY--------------------------------------------
PLK_Ddis_PLK1                 -----------YV-GA--------------------------------------------
8635_Tthe_SAK                 PLQESQINKNNQQRQEA-------------------------------------------
18358b_Tthe_PLK-Unclassified  -----------QA-GV--------------------------------------------
18380_Tthe_PLK-Unclassified   -----------TI-GV--------------------------------------------
21183_Tthe_SAK                -----------MI-FM--------------------------------------------
22503_Tthe_PLK-Unclassified   -----------NV-GI--------------------------------------------
5034_Tthe_SAK                 -----------KI-NIDYTSNQLMNNNQQYKINQEYNQNKLSNDFSSNNNKMNNNYVSNK
8829_Tthe_PLK-Unclassified    -----------CS-GV--------------------------------------------
SAK_Spur_SAK                  -----------EV-RV--------------------------------------------
PLK1_Spur_PLK1                -----------SV-GV--------------------------------------------
PLK2_Spur_PLK2                -----------VV-GV--------------------------------------------
n1170_Tthe_PLK-Unclassified   -----------SA-GV--------------------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ------------------------------------------------------------
AqueK200_Aque_PLK1            -----------SI-GV--------------------------------------------
AqueK201_Aque_SAK             -----------PV-KA--------------------------------------------
GK066_Glam_PLK-Unclassified   -----------SI-GV--------------------------------------------


PLK4_Hsap_SAK                 ---WFYD-----------------------------------------G--VKIH--K-T
PLK3_Hsap_PLK2                ---LFND-----------------------------------------G--THMALSA-N
PLK2_Hsap_PLK2                ---LFNN-----------------------------------------G--AHMSLLP-D
PLK1_Hsap_PLK1                ---LFND-----------------------------------------S--TRLILYN-D
polo_Dmel_PLK1                ---MFND-----------------------------------------T--TKLILLP-N
SAK_Dmel_SAK                  ---RFYS-----------------------------------------G--AKLLK-T-P
PLK5_Mmus_PLK2                ---LFRD-----------------------------------------G--SHMALRP-Q
PLK4_Mmus_SAK                 ---WFYD-----------------------------------------G--AKIH--K-T
PLK3_Mmus_PLK2                ---LFND-----------------------------------------G--THMALSA-N
PLK2_Mmus_PLK2                ---LFNN-----------------------------------------G--AHMSLLP-D
PLK1_Mmus_PLK1                ---LFND-----------------------------------------S--TRLILYN-D
plk-2_Cele_PLK1               ---LFND-----------------------------------------N--SRIMLDT-A
plk-1_Cele_PLK1               ---LFND-----------------------------------------N--SRIMLDQ-A
F55G1.8_Cele_PLK1             ---LFND-----------------------------------------N--TQMKVNS-A
CDC5_Scer_PLK1                ---LFNN-----------------------------------------G--TTVLRLA-D
zyg-1_Cele_SAK                ---IVEL-----------------------------------------DTRCRFEVAA-Q
PLK_Ddis_PLK1                 ---YFND-----------------------------------------S--TKIVTLI-E
8635_Tthe_SAK                 -----FD-----------------------------------------N--TKQALHN-V
18358b_Tthe_PLK-Unclassified  ---FFND-----------------------------------------S--TKIILNP-K
18380_Tthe_PLK-Unclassified   ---FFND-----------------------------------------F--TKIVIDP-E
21183_Tthe_SAK                ---KENN-----------------------------------------N--SKIQNVKK-
22503_Tthe_PLK-Unclassified   ---LLND-----------------------------------------G--NVTQIVDET
5034_Tthe_SAK                 INTEYNT-NKMINHDNPNRMSNEINKSNVDHYSNKNNSDFNKINVDYNS--NKINYDPN-
8829_Tthe_PLK-Unclassified    ---FFND-----------------------------------------S--TKVILDP-T
SAK_Spur_SAK                  ---QYND-----------------------------------------G--SMILVHA-A
PLK1_Spur_PLK1                ---LFND-----------------------------------------S--TRLLLHA-N
PLK2_Spur_PLK2                ---MFND-----------------------------------------K--SRISFTP-D
n1170_Tthe_PLK-Unclassified   ---VFND-----------------------------------------T--TKIILDP-K
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ------------------------------------------------------------
AqueK200_Aque_PLK1            ---LFND-----------------------------------------F--SKLLLGA-D
AqueK201_Aque_SAK             ---TFFPSS---------------------------------------G--SHLQED---
GK066_Glam_PLK-Unclassified   ---IFND-----------------------------------------E--SAAILSP-N


PLK4_Hsap_SAK                 EDFIQVI-----------------------EKT---------------------------
PLK3_Hsap_PLK2                RKTVHYN-----------------------PTS---------------------------
PLK2_Hsap_PLK2                KKTVHYY-----------------------AEL---------------------------
PLK1_Hsap_PLK1                GDSLQYI-----------------------ERD---------------------------
polo_Dmel_PLK1                QINVHFI-----------------------DKD---------------------------
SAK_Dmel_SAK                  SEGLKVY-----------------------DRN---------------------------
PLK5_Mmus_PLK2                GGHVSYQ-----------------------PDQ---------------------------
PLK4_Mmus_SAK                 ENLIHII-----------------------EKT---------------------------
PLK3_Mmus_PLK2                RKTVHYN-----------------------PTS---------------------------
PLK2_Mmus_PLK2                KKTVHYY-----------------------AEL---------------------------
PLK1_Mmus_PLK1                GDSLQYI-----------------------ERD---------------------------
plk-2_Cele_PLK1               GTQLTYI-----------------------EKT---------------------------
plk-1_Cele_PLK1               GNELTYI-----------------------EKS---------------------------
F55G1.8_Cele_PLK1             GNQLTFV-----------------------DEN---------------------------
CDC5_Scer_PLK1                AEEFWYI-----------------------SYD---------------------------
zyg-1_Cele_SAK                GNFVKRILIVEVDEMVQTVYVHRIPDRTVRGRN---------------------------
PLK_Ddis_PLK1                 SEIAYYM-----------------------EHA---------------------------
8635_Tthe_SAK                 KKPLQYF-----------------------SQQQQ-------------------------
18358b_Tthe_PLK-Unclassified  TEQFDYI-----------------------ERN---------------------------
18380_Tthe_PLK-Unclassified   GQYIEYY-----------------------EKQ---------------------------
21183_Tthe_SAK                KMSLHFP-----------------------TEQTNISQDIISTNTTCRNNITTTMTFPSP
22503_Tthe_PLK-Unclassified   FEHIQKV-----------------------QD----------------------------
5034_Tthe_SAK                 KANIDYS-----------------------SN----------------------------
8829_Tthe_PLK-Unclassified    TNNIEYI-----------------------ERL---------------------------
SAK_Spur_SAK                  TSTIKYM-----------------------DSQ---------------------------
PLK1_Spur_PLK1                ADTLEYI-----------------------ERD---------------------------
PLK2_Spur_PLK2                RSSVQYL-----------------------STD---------------------------
n1170_Tthe_PLK-Unclassified   AEYFEYI-----------------------YKK---------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ----DYI-----------------------SSR---------------------------
AqueK200_Aque_PLK1            GESMQHI-----------------------SQN---------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ALIVDYS-----------------------PSL---------------------------


PLK4_Hsap_SAK                 ---------GK-------------------------------------------------
PLK3_Hsap_PLK2                ---------TK-------------------------------------------------
PLK2_Hsap_PLK2                ---------GQ-------------------------------------------------
PLK1_Hsap_PLK1                ---------GT-------------------------------------------------
polo_Dmel_PLK1                ---------GK-------------------------------------------------
SAK_Dmel_SAK                  ---------GM-------------------------------------------------
PLK5_Mmus_PLK2                ---------GT-------------------------------------------------
PLK4_Mmus_SAK                 ---------GI-------------------------------------------------
PLK3_Mmus_PLK2                ---------TK-------------------------------------------------
PLK2_Mmus_PLK2                ---------GQ-------------------------------------------------
PLK1_Mmus_PLK1                ---------GT-------------------------------------------------
plk-2_Cele_PLK1               ---------EK-------------------------------------------------
plk-1_Cele_PLK1               ---------NK-------------------------------------------------
F55G1.8_Cele_PLK1             ---------NT-------------------------------------------------
CDC5_Scer_PLK1                ---------DR-------------------------------------------------
zyg-1_Cele_SAK                ---------GE-------------------------------------------------
PLK_Ddis_PLK1                 ---------KG-------------------------------------------------
8635_Tthe_SAK                 -----TQKD---------------------------------------------------
18358b_Tthe_PLK-Unclassified  ---------SS-------------------------------------------------
18380_Tthe_PLK-Unclassified   ---------PE-------------------------------------------------
21183_Tthe_SAK                SSQQFLAQNNNNQIIINQNIQRQKPSKSTHNNDNNHTSFDISYLKLDSSQMNSFSVERDF
22503_Tthe_PLK-Unclassified   ------------------------------------------------------------
5034_Tthe_SAK                 -----------------------------------------------------------N
8829_Tthe_PLK-Unclassified    ---------GN-------------------------------------------------
SAK_Spur_SAK                  ---------GK-------------------------------------------------
PLK1_Spur_PLK1                ---------GN-------------------------------------------------
PLK2_Spur_PLK2                ---------SK-------------------------------------------------
n1170_Tthe_PLK-Unclassified   ---------DQ-------------------------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ---------HH-------------------------------------------------
AqueK200_Aque_PLK1            ---------MT-------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ---------LD-------------------------------------------------


PLK4_Hsap_SAK                 ---------------------------SY-------------------------------
PLK3_Hsap_PLK2                ---------------------------H--------------------------------
PLK2_Hsap_PLK2                ---------------------------C--------------------------------
PLK1_Hsap_PLK1                ---------------------------E--------------------------------
polo_Dmel_PLK1                ---------------------------E--------------------------------
SAK_Dmel_SAK                  ---------------------------LL-------------------------------
PLK5_Mmus_PLK2                ---------------------------L--------------------------------
PLK4_Mmus_SAK                 ---------------------------SY-------------------------------
PLK3_Mmus_PLK2                ---------------------------H--------------------------------
PLK2_Mmus_PLK2                ---------------------------C--------------------------------
PLK1_Mmus_PLK1                ---------------------------E--------------------------------
plk-2_Cele_PLK1               ---------------------------E--------------------------------
plk-1_Cele_PLK1               ---------------------------E--------------------------------
F55G1.8_Cele_PLK1             ---------------------------EQ-------------------------------
CDC5_Scer_PLK1                ---------------------------EG-------------------------------
zyg-1_Cele_SAK                ---------------------------EE-------------------------------
PLK_Ddis_PLK1                 --------------------------TDG-------------------------------
8635_Tthe_SAK                 GDNQMFTQSQNNNTNKQMKGDNTLNGNLKYSSLSTNSQTLNKNDESYIHNYHQPRIRSQQ
18358b_Tthe_PLK-Unclassified  ---------------------------SK-------------------------------
18380_Tthe_PLK-Unclassified   ---------------------------EK-------------------------------
21183_Tthe_SAK                Q------------------------------------STAQFSSKSNV------------
22503_Tthe_PLK-Unclassified   ------------------------------------------------------------
5034_Tthe_SAK                 K------------------------------------INIEFNSNNKI------------
8829_Tthe_PLK-Unclassified    ---------------------------ER-------------------------------
SAK_Spur_SAK                  ---------------------------GQ-------------------------------
PLK1_Spur_PLK1                ---------------------------E--------------------------------
PLK2_Spur_PLK2                ---------------------------V--------------------------------
n1170_Tthe_PLK-Unclassified   ---------------------------DE-------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ---------------------------GS-------------------------------
AqueK200_Aque_PLK1            ---------------------------E--------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ---------------------------AA-------------------------------


PLK4_Hsap_SAK                 -------------------T----------------------------------------
PLK3_Hsap_PLK2                ------------------------------------------------------------
PLK2_Hsap_PLK2                ------------------------------------------------------------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  -------------------S----------------------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 -------------------N----------------------------------------
PLK3_Mmus_PLK2                ------------------------------------------------------------
PLK2_Mmus_PLK2                ------------------------------------------------------------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                -------------------W----------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 -------------------D-------G--------------------------------
8635_Tthe_SAK                 SQQNVNLREKSPSCQFIQKNQEISSQNN--------------------------------
18358b_Tthe_PLK-Unclassified  -------------------Q-------D--------------------------------
18380_Tthe_PLK-Unclassified   -------------------Y-------Q--------------------------------
21183_Tthe_SAK                -----IHTPTNVSISQKPPS-------NKNSYTYRDINPPSFAPSQQPTSLMRAKGSSKE
22503_Tthe_PLK-Unclassified   -------------------N-------Y--------------------------------
5034_Tthe_SAK                 -----N------------------------------------------------------
8829_Tthe_PLK-Unclassified    -------------------Q-------D--------------------------------
SAK_Spur_SAK                  -------------------R----------------------------------------
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   ------------------------------------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          -------------------I-------Y--------------------------------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 ------------------------------------------------LKSE--------
PLK3_Hsap_PLK2                ----------------------------------------------FSFSV---------
PLK2_Hsap_PLK2                ----------------------------------------------SVFPA---------
PLK1_Hsap_PLK1                ----------------------------------------------SYLTV---------
polo_Dmel_PLK1                ----------------------------------------------TYMTT---------
SAK_Dmel_SAK                  ------------------------------------------------DYSC--------
PLK5_Mmus_PLK2                ----------------------------------------------WTFTL---------
PLK4_Mmus_SAK                 ------------------------------------------------LKNE--------
PLK3_Mmus_PLK2                ----------------------------------------------FSFSM---------
PLK2_Mmus_PLK2                ----------------------------------------------SVFPA---------
PLK1_Mmus_PLK1                ----------------------------------------------SYLTV---------
plk-2_Cele_PLK1               ----------------------------------------------HYFDME--------
plk-1_Cele_PLK1               ----------------------------------------------HYFSMH--------
F55G1.8_Cele_PLK1             -----------------------------------------------FYTMN--------
CDC5_Scer_PLK1                -----------------------------------VA---------SHYLLS--------
zyg-1_Cele_SAK                -----------------------------------------------LITLTNNPFVYTS
PLK_Ddis_PLK1                 -----------------------------------RR---------VLNVT---------
8635_Tthe_SAK                 -----------CDGIKDLQNINKIQQNSQ------IK---------RNYSQ---------
18358b_Tthe_PLK-Unclassified  -----------------------------------FG---------AEYTL---------
18380_Tthe_PLK-Unclassified   -----------------------------------KS---------ITFTP---------
21183_Tthe_SAK                YIKTEPCDIDVNQTPR----LECLETENNENTSTAAC---------SKYSM---------
22503_Tthe_PLK-Unclassified   -----------------------------------VI---------QKYPI---------
5034_Tthe_SAK                 ------------------------------------------------------------
8829_Tthe_PLK-Unclassified    -----------------------------------FV---------QQFTL---------
SAK_Spur_SAK                  -----------------------------------AQWKKWIRWRQHCVDVE--------
PLK1_Spur_PLK1                ----------------------------------------------KYCRL---------
PLK2_Spur_PLK2                ----------------------------------------------HSFPL---------
n1170_Tthe_PLK-Unclassified   -----------------------------------IT---------EKHSL---------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          -----------------------------------LR---------KSFTI---------
AqueK200_Aque_PLK1            ----------------------------------------------QFLTL---------
AqueK201_Aque_SAK             --------------------------------------------------Q---------
GK066_Glam_PLK-Unclassified   -----------------------------------FD---------RAL-FE--------


PLK4_Hsap_SAK                 --SEVNSLKEEIKMYMDHAN--EGHRIC-------------LA-LESIISEE-ERKTRSA
PLK3_Hsap_PLK2                -GAVPRALQPQ-------------------------LGIL-RY-FASYMEQ-HLM-----
PLK2_Hsap_PLK2                -TDAPEQFISQ-------------------------VTVL-KY-FSHYMEE-NLM-----
PLK1_Hsap_PLK1                -SSHPNSLMKK-------------------------ITLL-KY-FRNYMSE-HLL-----
polo_Dmel_PLK1                -TDYCKSLDKK-------------------------MKLL-SY-FKRYMIE-HLV-----
SAK_Dmel_SAK                  --SESRSL-------IEHGN--ECFTHC-------------VN-ISNALEVA---QTKDN
PLK5_Mmus_PLK2                -RDVPSPLRAK-------------------------LAVL-RL-FACYMQR-RLR-----
PLK4_Mmus_SAK                 --NEVTSLKEEVKVYMDHAN--EGHRIC-------------LS-LESVISEE-EKRSRGS
PLK3_Mmus_PLK2                -GSVPRALQPQ-------------------------LGIL-RY-FASYMEQ-HLM-----
PLK2_Mmus_PLK2                -TDAPEQFISQ-------------------------VTVL-KY-FSHYMEE-NLM-----
PLK1_Mmus_PLK1                -SSHPNSLMKK-------------------------ITLL-NY-FRNYMSE-HLL-----
plk-2_Cele_PLK1               -SAIPSGLQKK-------------------------MTLL-KY-FRSYMND-HLL-----
plk-1_Cele_PLK1               SGEMPGLLNKK-------------------------VTLL-KY-FRSYMND-HLV-----
F55G1.8_Cele_PLK1             -DQVPMNLQTK-------------------------INIF-SN-VQSYMNT-HLE-----
CDC5_Scer_PLK1                --EKPRELSRH-------------------------LEVV-DF-FAKYMKA-NLS-----
zyg-1_Cele_SAK                YSQMPKEVQND-------------------------YMRLQKM-VAVTISG-RVA-----
PLK_Ddis_PLK1                 -QQHPHDTQKK-------------------------VTLI-KY-FLNHFTN-SDT-----
8635_Tthe_SAK                 -QITPKEMQTN-------------------------SNIQ-KLEYANRISQ-LCA-----
18358b_Tthe_PLK-Unclassified  -KDYPESLQKK-------------------------LTLL-QH-FRSFLEG-EDK-----
18380_Tthe_PLK-Unclassified   -DNYPQELKKK-------------------------VTLL-EH-FRSYLQG-DHG-----
21183_Tthe_SAK                -NTTNRSFNKG-------------------------LNTS-KS-FSSFIAD-QTN-----
22503_Tthe_PLK-Unclassified   -KQIPPSCQNL-------------------------FRLT-TN-IKEYFLN-KYK-----
5034_Tthe_SAK                 ----NGYVSNK-------------------------VTSE-VN-KYNYESN-HNK-----
8829_Tthe_PLK-Unclassified    -KDYPPEMKKK-------------------------VTLL-SH-FKSYLEE-QMQ-----
SAK_Spur_SAK                  --SAIASLESRHGYGPFFPLILSRKPLQESYQQGNKVTAS-KN-IRTSAATSHTT-----
PLK1_Spur_PLK1                -GSYDSTLHKK-------------------------VTLL-KY-FRNYMSE-HLL-----
PLK2_Spur_PLK2                -SSVPSRLSKK-------------------------VTLL-DY-FATYMDE-HLI-----
n1170_Tthe_PLK-Unclassified   -TEYPTDLQKK-------------------------VTLL-QH-FRHYLMT-EVN-----
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          -DAYPDELKSK-------------------------VYLL-KH-FEKYIME-RLY-----
AqueK200_Aque_PLK1            -SQYPESMHKK-------------------------VTLI-KY-FRDYMSE-HLL-----
AqueK201_Aque_SAK             --------------------------------SRKATSGL-HH-RRAHSLE-DVC-----
GK066_Glam_PLK-Unclassified   -EGTTILSEKK-------------------------FKLL-SF-FRDYLEN-RSI-----


PLK4_Hsap_SAK                 PFFPIIIGRKPGST----SSPKALSPPPSVDSNYPTRERASFNRMVMHSA-ASPTQAP-I
PLK3_Hsap_PLK2                ------------------------------------------------------------
PLK2_Hsap_PLK2                ------------------------------------------------------------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  SCFPVTIGRRPITD----VQPAQR-LDGL--------------RDTTNIAFSTPKSNQGS
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 SFFPIIVGRKPGNT----SSPKALSAPP-VDPSCCKGEQASASRLSVNSA-AFPTQSP-G
PLK3_Mmus_PLK2                ------------------------------------------------------------
PLK2_Mmus_PLK2                ------------------------------------------------------------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                ------------------------------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ------------------------------------------------------------
8635_Tthe_SAK                 ------------------------------------------------------------
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   ------------------------------------------------------------
21183_Tthe_SAK                ------------------------------------------------------------
22503_Tthe_PLK-Unclassified   ------------------------------------------------------------
5034_Tthe_SAK                 ------------------------------------------------------------
8829_Tthe_PLK-Unclassified    ------------------------------------------------------------
SAK_Spur_SAK                  ---------PATTATSTNTVPPSTT----------PHPGGPTQAC------------P-Q
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   ------------------------------------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ------------------------------------------------------------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 --L-NPSM----------------------VTNEGLGLTTTAS-----G-----------
PLK3_Hsap_PLK2                ------------------------------------------K-----G-----------
PLK2_Hsap_PLK2                ------------------------------------------D-----G-----------
PLK1_Hsap_PLK1                ------------------------------------------K-----A-----------
polo_Dmel_PLK1                ------------------------------------------K-----A-----------
SAK_Dmel_SAK                  --I-NFSL----------------------STISST-RNTSDF-----G-----------
PLK5_Mmus_PLK2                ------------------------------------------E-----E-----------
PLK4_Mmus_SAK                 --L-SPST----------------------VTVEGLGHTATAT-----G-----------
PLK3_Mmus_PLK2                ------------------------------------------K-----G-----------
PLK2_Mmus_PLK2                ------------------------------------------D-----G-----------
PLK1_Mmus_PLK1                ------------------------------------------K-----A-----------
plk-2_Cele_PLK1               ------------------------------------------Q-----A-----------
plk-1_Cele_PLK1               ------------------------------------------K-----A-----------
F55G1.8_Cele_PLK1             ------------------------------------------A-----D-----------
CDC5_Scer_PLK1                ------------------------------------------R-----V-----------
zyg-1_Cele_SAK                ------------------------------------------K-----V-----------
PLK_Ddis_PLK1                 ------------------------------------------TNLLINT-----------
8635_Tthe_SAK                 ------------------------------------------K-----G-----------
18358b_Tthe_PLK-Unclassified  ------------------------------------------K-----A-----------
18380_Tthe_PLK-Unclassified   ------------------------------------------S-----N-----------
21183_Tthe_SAK                ------------------------------------------E-----I---DKYSNNIQ
22503_Tthe_PLK-Unclassified   ------------------------------------------L-----I-----------
5034_Tthe_SAK                 ------------------------------------------Y-----GNEQNQYKIKYE
8829_Tthe_PLK-Unclassified    ------------------------------------------K-----Q-----------
SAK_Spur_SAK                  GSVTSPSVMAAPTASVCSFDGTICSVARSVQGKDRTRHRKTDK-----G-----------
PLK1_Spur_PLK1                ------------------------------------------K-----A-----------
PLK2_Spur_PLK2                ------------------------------------------K-----G-----------
n1170_Tthe_PLK-Unclassified   ------------------------------------------K-----K-----------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ------------------------------------------G-----E-----------
AqueK200_Aque_PLK1            ------------------------------------------K-----A-----------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------V-----PI----------


PLK4_Hsap_SAK                 --T---------------------------------------------D------ISSNS
PLK3_Hsap_PLK2                --GD--------------------------------------------L------PSV--
PLK2_Hsap_PLK2                --GD--------------------------------------------L------PSV--
PLK1_Hsap_PLK1                --GA--------------------------------------------N------ITP--
polo_Dmel_PLK1                --GA--------------------------------------------N------NVN--
SAK_Dmel_SAK                  --T---------------------------------------------N------CSR--
PLK5_Mmus_PLK2                --GT--------------------------------------------V------PMP--
PLK4_Mmus_SAK                 --T---------------------------------------------G------V----
PLK3_Mmus_PLK2                --GD--------------------------------------------L------PSV--
PLK2_Mmus_PLK2                --GD--------------------------------------------L------PSV--
PLK1_Mmus_PLK1                --GA--------------------------------------------N------ITP--
plk-2_Cele_PLK1               --GQ--------------------------------------------Q------VTR--
plk-1_Cele_PLK1               --GE--------------------------------------------G------SEQ--
F55G1.8_Cele_PLK1             --T---------------------------------------------H------LEAED
CDC5_Scer_PLK1                --S---------------------------------------------T------FGREE
zyg-1_Cele_SAK                --T---------------------------------------------FRRPSQFPDAQA
PLK_Ddis_PLK1                 --GA--------------------------------------------T------SSSIN
8635_Tthe_SAK                 --DH--------------------------------------------N------F--L-
18358b_Tthe_PLK-Unclassified  --DS--------------------------------------------I------KMPQ-
18380_Tthe_PLK-Unclassified   --NQ--------------------------------------------N------ANNNY
21183_Tthe_SAK                LNQQ----NS---------------------------------NIITSQ------IS-P-
22503_Tthe_PLK-Unclassified   --CP--------------------------------------------K------V--E-
5034_Tthe_SAK                 FSSP----KMNTEQNTSRLNTDYKGTRLNTDFNNTRDNTECNTQ----------------
8829_Tthe_PLK-Unclassified    --NI--------------------------------------------Q------I--E-
SAK_Spur_SAK                  --GSSKEAC---------------------------------------K------VT-SQ
PLK1_Spur_PLK1                --GA--------------------------------------------A------MTP--
PLK2_Spur_PLK2                --ID--------------------------------------------S------DKK--
n1170_Tthe_PLK-Unclassified   --VC--------------------------------------------A------ENGST
n808_Tthe_PLK-Unclassified    -----------------------------------------------------------E
CC1G_07437_Ccin_PLK1          --YE---------------------------------------------------YTF--
AqueK200_Aque_PLK1            --GG--------------------------------------------S------VGE--
AqueK201_Aque_SAK             -----------------------------------------------------------R
GK066_Glam_PLK-Unclassified   --PA--------------------------------------------A------DRPKE


PLK4_Hsap_SAK                 ---------L-------------KD--CLP------------------------K----S
PLK3_Hsap_PLK2                ----------E---------------------------------E--VE-----V---PA
PLK2_Hsap_PLK2                ----------T---------------------------------D--IR---------RP
PLK1_Hsap_PLK1                ----------R--------------------------------EG--DE-----L---AR
polo_Dmel_PLK1                ----------I--------------------------------ES--DQ-----I---SR
SAK_Dmel_SAK                  -----------------------SN--MLA------------------------A---HQ
PLK5_Mmus_PLK2                ----------A---------------------------------T--PA---------SP
PLK4_Mmus_SAK                 -----------------------SS--SLP------------------------K----S
PLK3_Mmus_PLK2                ----------E---------------------------------E--AE-----V---PA
PLK2_Mmus_PLK2                ----------T---------------------------------D--IR---------RP
PLK1_Mmus_PLK1                ----------R--------------------------------EG--DE-----L---AR
plk-2_Cele_PLK1               ----------K--------------------------------VG--DD-----L---AR
plk-1_Cele_PLK1               ----------R--------------------------------AG--DD-----L---AR
F55G1.8_Cele_PLK1             ---------QC------------VN--KVP-------------PL--RN-----F---AR
CDC5_Scer_PLK1                ---------Y--------------H--K-------------------------------D
zyg-1_Cele_SAK                ---------QL------------M-----E-------------NG--DL-----R---IK
PLK_Ddis_PLK1                 NNNNNNVENVT---------N-NNN--NNS-------------NN--SS-----N---IN
8635_Tthe_SAK                 --------------------L----------------------EK--KSSSNSNNNCQ-Q
18358b_Tthe_PLK-Unclassified  ---------NE---------A----------------------SG--EP-----K---SS
18380_Tthe_PLK-Unclassified   D--------VN---------P-PST--FLD-------------NQ--TG-----K---KM
21183_Tthe_SAK                --------------------V----------------------KV--GD-----DLDVSK
22503_Tthe_PLK-Unclassified   --------------------L----------------------QE--GD-----F---EK
5034_Tthe_SAK                 -------------------------------------------RLNTEQ-----NT--AR
8829_Tthe_PLK-Unclassified    ---------VP---------Q----------------------FQ--GD-----L---QP
SAK_Spur_SAK                  -----------------------AS--SHP------------------------E---GK
PLK1_Spur_PLK1                ----------R--------------------------------ES--DS-----M---AR
PLK2_Spur_PLK2                ----------D------------------GIRSPSPKRKGVDKPG--PV-----N---SA
n1170_Tthe_PLK-Unclassified   Q--------AT---------L-YND--SKF-------------QM--QP-----N---QP
n808_Tthe_PLK-Unclassified    R---------------------KTD--ESN-------------KL--NP-----------
CC1G_07437_Ccin_PLK1          ----------E--------------------------------DV--ER-----T---KG
AqueK200_Aque_PLK1            ----------R--------------------------------EI--DD-----G---VR
AqueK201_Aque_SAK             ---------G-------------ND--EI-------------------------------
GK066_Glam_PLK-Unclassified   ---------DEELKRVIEQERMNNQEIDFKR------------LT--KGL----P---LP


PLK4_Hsap_SAK                 AQL----LKSV----------------------------FVKNVG-WATQLTSGA-----
PLK3_Hsap_PLK2                PPL----LLQW----------------------------VKTDQA-LLMLFSDGT-----
PLK2_Hsap_PLK2                RLY----LLQW----------------------------LKSDKA-LMMLFNDGT-----
PLK1_Hsap_PLK1                LPY----LRTW----------------------------FRTRSA-IILHLSNGS-----
polo_Dmel_PLK1                MPH----LHSW----------------------------FRTTCA-VVMHLTNGS-----
SAK_Dmel_SAK                  NIP----IKRI----------------------------NVPEIG-IATELSHGV-----
PLK5_Mmus_PLK2                DIS----LLSF----------------------------IADSQA-MVMLFSNGT-----
PLK4_Mmus_SAK                 AQL----LKSV----------------------------FVKNVG-WATQLTSGA-----
PLK3_Mmus_PLK2                PPL----LLQW----------------------------VKTDQA-LLMLFSDGT-----
PLK2_Mmus_PLK2                RLY----LLQW----------------------------LKSDKA-LMMLFNDGT-----
PLK1_Mmus_PLK1                LPY----LRTW----------------------------FRTRSA-IILHLSNGT-----
plk-2_Cele_PLK1               LPT----LRVW----------------------------FRTKSA-IVLHLSNGT-----
plk-1_Cele_PLK1               LPT----LRVW----------------------------FRTKSA-IVLHLSNGT-----
F55G1.8_Cele_PLK1             LPT----IQNW----------------------------FETKSA-VIFHLSNGT-----
CDC5_Scer_PLK1                DVF----LRRY----------------------------TRYKPF-VMFELSDGT-----
zyg-1_Cele_SAK                L----------------------------------------PRSV-IVRKMDNGEIFNCI
PLK_Ddis_PLK1                 PIY----VKKW----------------------------IKFDNG-IAFRLSDKT-----
8635_Tthe_SAK                 NVQ----SSKNIRSLSNSQFTINSNIKQKIQKDTSELSIQVTDRQ-ITFQGNEQN-----
18358b_Tthe_PLK-Unclassified  KIY----VKKW----------------------------LRTKNA-ILFRLSNKV-----
18380_Tthe_PLK-Unclassified   LYY----VKKW----------------------------VKTKNA-ILFRLQNKI-----
21183_Tthe_SAK                IKT----KNGY--------IE------------------ITSDHS-LLVESCNGR-----
22503_Tthe_PLK-Unclassified   EVY----LKKF----------------------------ISTKQA-SFFRFSNKD-----
5034_Tthe_SAK                 LTTEQYNPQRV----------------------------ISKNKA-IMFSMDNLQ-----
8829_Tthe_PLK-Unclassified    YVY----VKKW----------------------------MKTKHA-IMFRLSNKI-----
SAK_Spur_SAK                  DGV----LKSV----------------------------FVPNIG-WASQMSSGE-----
PLK1_Spur_PLK1                LPF----LQSW----------------------------FRTKSA-IVLHLSNGT-----
PLK2_Spur_PLK2                QPY----LEKW----------------------------NRTGKA-ITMYLSNGT-----
n1170_Tthe_PLK-Unclassified   LPY----LKKW----------------------------MQTRHA-IMFRLSNKI-----
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          MEW----VQKY----------------------------LRMKHV-IVFKMSHDV-----
AqueK200_Aque_PLK1            LPF----LRAW----------------------------SRTRSA-IVFHLSNGT-----
AqueK201_Aque_SAK             -MK----LSNC----------------------------FSGEQS-VSFSLKDND-----
GK066_Glam_PLK-Unclassified   QLF----LKKW----------------------------KLYDDGTLCLLFNTKV-----


PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                ------------------------------------------------------------
PLK2_Hsap_PLK2                ------------------------------------------------------------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                ------------------------------------------------------------
PLK2_Mmus_PLK2                ------------------------------------------------------------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                ------------------------------------------------------------
zyg-1_Cele_SAK                DGIATQKQAVSGITLTKVNEVYKYLIRFEQCLNGMDRGMVCFPIVFSAGTNMVGSSPSSL
PLK_Ddis_PLK1                 ------------------------------------------------------------
8635_Tthe_SAK                 ------------------------------------------------------------
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   ------------------------------------------------------------
21183_Tthe_SAK                ------------------------------------------------------------
22503_Tthe_PLK-Unclassified   ------------------------------------------------------------
5034_Tthe_SAK                 ------------------------------------------------------------
8829_Tthe_PLK-Unclassified    ------------------------------------------------------------
SAK_Spur_SAK                  ------------------------------------------------------------
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   ------------------------------------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ------------------------------------------------------------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 --------------------------------------------VWVQF-----------
PLK3_Hsap_PLK2                --------------------------------------------VQVNF-----------
PLK2_Hsap_PLK2                --------------------------------------------FQVNF-----------
PLK1_Hsap_PLK1                --------------------------------------------VQINF-----------
polo_Dmel_PLK1                --------------------------------------------VQLNF-----------
SAK_Dmel_SAK                  --------------------------------------------VQVQF-----------
PLK5_Mmus_PLK2                --------------------------------------------VQVSL-----------
PLK4_Mmus_SAK                 --------------------------------------------VWVQF-----------
PLK3_Mmus_PLK2                --------------------------------------------VQVNF-----------
PLK2_Mmus_PLK2                --------------------------------------------FQVNF-----------
PLK1_Mmus_PLK1                --------------------------------------------VQINF-----------
plk-2_Cele_PLK1               --------------------------------------------VQINF-----------
plk-1_Cele_PLK1               --------------------------------------------VQINF-----------
F55G1.8_Cele_PLK1             --------------------------------------------VQINF-----------
CDC5_Scer_PLK1                --------------------------------------------FQFNF-----------
zyg-1_Cele_SAK                MPSGSSQTSRFPFSNLSNNQPSLVPHSAPFLTKPTSSQRASSANVQRRV-----------
PLK_Ddis_PLK1                 --------------------------------------------IQVNY-----------
8635_Tthe_SAK                 --------------------------------------------EKINF-----------
18358b_Tthe_PLK-Unclassified  --------------------------------------------VQVIF-----------
18380_Tthe_PLK-Unclassified   --------------------------------------------VQVSF-----------
21183_Tthe_SAK                --------------------------------------------LLFKI-----------
22503_Tthe_PLK-Unclassified   --------------------------------------------LQVIF-----------
5034_Tthe_SAK                 --------------------------------------------GKLNMENANNRISVEQ
8829_Tthe_PLK-Unclassified    --------------------------------------------VQVSF-----------
SAK_Spur_SAK                  --------------------------------------------VRVQY-----------
PLK1_Spur_PLK1                --------------------------------------------VQINF-----------
PLK2_Spur_PLK2                --------------------------------------------LQVNF-----------
n1170_Tthe_PLK-Unclassified   --------------------------------------------VQVQF-----------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          --------------------------------------------LQFNF-----------
AqueK200_Aque_PLK1            --------------------------------------------LQINF-----------
AqueK201_Aque_SAK             --------------------------------------------VPSSS-----------
GK066_Glam_PLK-Unclassified   --------------------------------------------FQVNF-----------


PLK4_Hsap_SAK                 -------------------------------N-DG-------------------------
PLK3_Hsap_PLK2                ------------------------------YG-DH-------------------------
PLK2_Hsap_PLK2                ------------------------------YH-DH-------------------------
PLK1_Hsap_PLK1                ------------------------------FQ-DH-------------------------
polo_Dmel_PLK1                -------------------------------S-DH-------------------------
SAK_Dmel_SAK                  -------------------------------Y-DG-------------------------
PLK5_Mmus_PLK2                ------------------------------KT-SQ-------------------------
PLK4_Mmus_SAK                 -------------------------------N-DG-------------------------
PLK3_Mmus_PLK2                ------------------------------YG-DH-------------------------
PLK2_Mmus_PLK2                ------------------------------YH-DH-------------------------
PLK1_Mmus_PLK1                ------------------------------FQ-DH-------------------------
plk-2_Cele_PLK1               ------------------------------FN-DH-------------------------
plk-1_Cele_PLK1               ------------------------------FN-DH-------------------------
F55G1.8_Cele_PLK1             -------------------------------L-DH-------------------------
CDC5_Scer_PLK1                -------------------------------K-DH-------------------------
zyg-1_Cele_SAK                -------------------------------STDENSSPSVAPSKYKIKIDPTTQKVRSI
PLK_Ddis_PLK1                 -------------------------------L-DK-------------------------
8635_Tthe_SAK                 ------------------------------TK-SP-------------------------
18358b_Tthe_PLK-Unclassified  -------------------------------Q-DS-------------------------
18380_Tthe_PLK-Unclassified   -------------------------------S-DK-------------------------
21183_Tthe_SAK                ------------------------------SK-DG-------------------------
22503_Tthe_PLK-Unclassified   -------------------------------I-DK-------------------------
5034_Tthe_SAK                 NINGRFNNEIMKTNNENLILKNGNAQNILNTN-AH-------------------------
8829_Tthe_PLK-Unclassified    -------------------------------Q-DK-------------------------
SAK_Spur_SAK                  -------------------------------N-DG-------------------------
PLK1_Spur_PLK1                ------------------------------FE-DH-------------------------
PLK2_Spur_PLK2                ------------------------------FE-DH-------------------------
n1170_Tthe_PLK-Unclassified   -------------------------------S-DK-------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          -------------------------------Y-DH-------------------------
AqueK200_Aque_PLK1            ------------------------------FQ-DH-------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   -------------------------------A-DH-------------------------


PLK4_Hsap_SAK                 ----SQLVV-----------------QAGV------------------------------
PLK3_Hsap_PLK2                ----TKLIL-----------------SGWE------------------------------
PLK2_Hsap_PLK2                ----TKIII-----------------CSQN------------------------------
PLK1_Hsap_PLK1                ----TKLIL-----------------CPLM------------------------------
polo_Dmel_PLK1                ----MKLIL-----------------CPRM------------------------------
SAK_Dmel_SAK                  ----SVVSV-----------------IPSM------------------------------
PLK5_Mmus_PLK2                ----TQLVL-----------------SGED------------------------------
PLK4_Mmus_SAK                 ----SQLVV-----------------QAGV------------------------------
PLK3_Mmus_PLK2                ----TKLIL-----------------SGWE------------------------------
PLK2_Mmus_PLK2                ----TKIII-----------------CNQS------------------------------
PLK1_Mmus_PLK1                ----TKLIL-----------------CPLM------------------------------
plk-2_Cele_PLK1               ----IKMVL-----------------CPLM------------------------------
plk-1_Cele_PLK1               ----VKMMM-----------------CPLM------------------------------
F55G1.8_Cele_PLK1             ----VKMVL-----------------CPLL------------------------------
CDC5_Scer_PLK1                ----HKMAI-----------------SDGG------------------------------
zyg-1_Cele_SAK                QATDGRVLR-----------------CSTS------------------------------
PLK_Ddis_PLK1                 ----SRIIV-----------------SSK-------------------------------
8635_Tthe_SAK                 ----TQIQTRNNSKSFSQSVNCAPIASSKERKVSFVAQSADLQEQIQIIQSKSTQ-----
18358b_Tthe_PLK-Unclassified  ----SEIIL-----------------SSEL------------------------------
18380_Tthe_PLK-Unclassified   ----TEIIL-----------------NSIM------------------------------
21183_Tthe_SAK                ----QKIQI-----------------NKLID-KPM-------------------------
22503_Tthe_PLK-Unclassified   ----SEVVI-----------------TQQN------------------------------
5034_Tthe_SAK                 ----PKIID-----------------KKQKSEVPLI------------------SQIANQ
8829_Tthe_PLK-Unclassified    ----TEILL-----------------SSEN------------------------------
SAK_Spur_SAK                  ----SMILV-----------------HATT------------------------------
PLK1_Spur_PLK1                ----TKLIV-----------------CPMM------------------------------
PLK2_Spur_PLK2                ----TKVIL-----------------SHNN------------------------------
n1170_Tthe_PLK-Unclassified   ----TEILL-----------------NSTD------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ----SKLIL-----------------SSNG------------------------------
AqueK200_Aque_PLK1            ----TKIII-----------------CPLM------------------------------
AqueK201_Aque_SAK             --------V-----------------YSQ-------------------------------
GK066_Glam_PLK-Unclassified   ----SKVVV-----------------AH--------------------------------


PLK4_Hsap_SAK                 -------------------SSI--SYT------SPNG--QT-------------------
PLK3_Hsap_PLK2                ------------------PLLV--TFV------ARNR--SA-------------------
PLK2_Hsap_PLK2                -----------------EEYLL--TYI------NEDR--IS-------------------
PLK1_Hsap_PLK1                -------------------AAV--TYI------DEKR--DF-------------------
polo_Dmel_PLK1                -------------------SAI--TYM------DQEK--NF-------------------
SAK_Dmel_SAK                  -----------------QGGGI--TYT------QPNG--TS-------------------
PLK5_Mmus_PLK2                -----------------EDLLL--TLQ------EPGGPAVG-------------------
PLK4_Mmus_SAK                 -------------------SSI--SYT------SPDG--QT-------------------
PLK3_Mmus_PLK2                ------------------PLLV--TFV------ARNR--SA-------------------
PLK2_Mmus_PLK2                -----------------EEYLL--TYI------NEDR--IS-------------------
PLK1_Mmus_PLK1                -------------------AAV--TYI------NEKR--DF-------------------
plk-2_Cele_PLK1               -------------------QAV--TFI------DENK--RM-------------------
plk-1_Cele_PLK1               -------------------QAV--TFI------DQNK--RM-------------------
F55G1.8_Cele_PLK1             -----------------K--SV--TFI------EENK--RV-------------------
CDC5_Scer_PLK1                -----------------K--LV--TYI------SPSH--ES-------------------
zyg-1_Cele_SAK                -----------------K--ADQFIFTDPAIRPDDQR--FM-------------------
PLK_Ddis_PLK1                 -----------------D--MV--TFV------PYRG--QI-------------------
8635_Tthe_SAK                 ---------------QTG--AV--NFA------DSKT--QY-------------------
18358b_Tthe_PLK-Unclassified  -----------------R--AV--TYV------NRKK--QR-------------------
18380_Tthe_PLK-Unclassified   -----------------K--IV--TFN------NKQG--IR-------------------
21183_Tthe_SAK                ------------------------------------------------------------
22503_Tthe_PLK-Unclassified   -----------------K--NL--YFK------DKNG--TQ-------------------
5034_Tthe_SAK                 PMRSSQVQLTQQQQQQNI--PI--TFL------NEDR--DLYKKQEKFDKVKHFKNQTSD
8829_Tthe_PLK-Unclassified    -----------------K--MV--TYV------DRKG--TR-------------------
SAK_Spur_SAK                  -------------------STI--KYM------DSQG--KG-------------------
PLK1_Spur_PLK1                -------------------GAA--TYI------DAKR--NF-------------------
PLK2_Spur_PLK2                -----------------NDHLV--TYI------NESR--TP-------------------
n1170_Tthe_PLK-Unclassified   -----------------K--IV--SFM------NKKG--ER-------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          -------------------LLI--THI------DKSY--KM-------------------
AqueK200_Aque_PLK1            -------------------QAV--TYI------DEQK--PS-------------------
AqueK201_Aque_SAK             ------------------RDPV--TCI------SRNS--S--------------------
GK066_Glam_PLK-Unclassified   -----------------R--SV--TFM------SEKR--EI-------------------


PLK4_Hsap_SAK                 -------------------------------------------T------RYGENEKLP-
PLK3_Hsap_PLK2                -------------------------------------------C------TYLASHLRQL
PLK2_Hsap_PLK2                -------------------------------------------T------TFRLTTLLMS
PLK1_Hsap_PLK1                -------------------------------------------R------TYRLSLLEEY
polo_Dmel_PLK1                -------------------------------------------R------TYRFSTIVEN
SAK_Dmel_SAK                  -------------------------------------------T------HFGKGDDLP-
PLK5_Mmus_PLK2                -------------------------------------------V------SYTLDVLRSH
PLK4_Mmus_SAK                 -------------------------------------------T------RYGENEKLP-
PLK3_Mmus_PLK2                -------------------------------------------C------TYLASHLRQL
PLK2_Mmus_PLK2                -------------------------------------------T------TFRLTTLLMS
PLK1_Mmus_PLK1                -------------------------------------------Q------TYRLSLLEEY
plk-2_Cele_PLK1               -------------------------------------------F------TYKFSHLAEN
plk-1_Cele_PLK1               -------------------------------------------L------TYKLNNLQRN
F55G1.8_Cele_PLK1             -------------------------------------------S------TFTFANILTN
CDC5_Scer_PLK1                -------------------------------------------T------TYPLVEVLKY
zyg-1_Cele_SAK                -------------------------------------------R------TDR-------
PLK_Ddis_PLK1                 -------------------------------------------I------TGTLNYFK-N
8635_Tthe_SAK                 -------------------------------------------QSNDTNSSFPVSPLS--
18358b_Tthe_PLK-Unclassified  -------------------------------------------E------TFPLSTAMES
18380_Tthe_PLK-Unclassified   -------------------------------------------Q------NYPLTPDLKM
21183_Tthe_SAK                -----------------------------------------------------EKHYTLN
22503_Tthe_PLK-Unclassified   -------------------------------------------K------IHTLNHEDKS
5034_Tthe_SAK                 NANYSLNNTNNINGSNEYNKEFFNAQYQQQLQDQQEKMMNSKVN------TYRNSQIFES
8829_Tthe_PLK-Unclassified    -------------------------------------------T------DYPLSTALES
SAK_Spur_SAK                  -------------------------------------------Q------SYGRNAVLP-
PLK1_Spur_PLK1                -------------------------------------------R------TFRLNLIEKH
PLK2_Spur_PLK2                -------------------------------------------T------TYRVLHITHH
n1170_Tthe_PLK-Unclassified   -------------------------------------------F------HYPLADAMNS
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          -------------------------------------------T------RWTLEDVMAF
AqueK200_Aque_PLK1            -------------------------------------------S------QSDSPSL---
AqueK201_Aque_SAK             ---------------------------------------------------------LD-
GK066_Glam_PLK-Unclassified   -------------------------------------------Y------TYPSEYLKDD


PLK4_Hsap_SAK                 ----------------------DYI-----------------------------------
PLK3_Hsap_PLK2                G-------------CS-PDLR-QRL-----------------------------------
PLK2_Hsap_PLK2                G-------------CS-SELK-NRM-----------------------------------
PLK1_Hsap_PLK1                G-------------CC-KELA-SRL-----------------------------------
polo_Dmel_PLK1                G-------------VS-KDLY-QKI-----------------------------------
SAK_Dmel_SAK                  ----------------------FPV-----------------------------------
PLK5_Mmus_PLK2                G-------------FT-LAVH-HHL-----------------------------------
PLK4_Mmus_SAK                 ----------------------EYI-----------------------------------
PLK3_Mmus_PLK2                G-------------CS-PDLR-QRL-----------------------------------
PLK2_Mmus_PLK2                G-------------CS-LELK-NRM-----------------------------------
PLK1_Mmus_PLK1                G-------------CC-KELA-SRL-----------------------------------
plk-2_Cele_PLK1               G-------------CP-EKFL-HRI-----------------------------------
plk-1_Cele_PLK1               G-------------CP-EKFL-HRL-----------------------------------
F55G1.8_Cele_PLK1             S-------------CP-KKYL-SRI-----------------------------------
CDC5_Scer_PLK1                G-------------EI-PGYPESNF-----------------------------------
zyg-1_Cele_SAK                -------------------VP-DRA-----------------------------------
PLK_Ddis_PLK1                 --------------GD-KKIS-EKI-----------------------------------
8635_Tthe_SAK                 ------------------------------------------------------------
18358b_Tthe_PLK-Unclassified  --------------QN-KEMS-KRL-----------------------------------
18380_Tthe_PLK-Unclassified   --------------YS-PEME-KRL-----------------------------------
21183_Tthe_SAK                N-------------LP-AKYY-ALY-----------------------------------
22503_Tthe_PLK-Unclassified   S-------------LP-HNIR-KRI-----------------------------------
5034_Tthe_SAK                 Q-------------VG-TQRV-QAVKSKSRIQSGLKTDVSDSETNSISNQNSTTNNLEYY
8829_Tthe_PLK-Unclassified    --------------SN-TEMS-KRL-----------------------------------
SAK_Spur_SAK                  ----------------------SHI-----------------------------------
PLK1_Spur_PLK1                G-------------CT-PDLY-DRI-----------------------------------
PLK2_Spur_PLK2                G-------------CT-KALH-TRL-----------------------------------
n1170_Tthe_PLK-Unclassified   --------------TN-QDMT-KRL-----------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          SLHPPQGASGDEIKFN-QRMV-DKL-----------------------------------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ----------------------SSV-----------------------------------
GK066_Glam_PLK-Unclassified   R-------------FSFKELR-RRV-----------------------------------


PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                ------------------------------------------------------------
PLK2_Hsap_PLK2                ------------------------------------------------------------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                ------------------------------------------------------------
PLK2_Mmus_PLK2                ------------------------------------------------------------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                ------------------------------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ------------------------------------------------------------
8635_Tthe_SAK                 -----------------------------------------------------TQGLKAN
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   ------------------------------------------------------------
21183_Tthe_SAK                ------------------------------------------------------------
22503_Tthe_PLK-Unclassified   ------------------------------------------------------------
5034_Tthe_SAK                 ESPRINTLNLMLSPERRIPTTNNSTAVKNNSQMKNLLSGNKDNSSCKNNSNNTSRKNTSK
8829_Tthe_PLK-Unclassified    ------------------------------------------------------------
SAK_Spur_SAK                  ------------------------------------------------------------
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   ------------------------------------------------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ------------------------------------------------------------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 --------------------------------KQKLQCL---------------------
PLK3_Hsap_PLK2                --------------------------------RYALRLL---------------------
PLK2_Hsap_PLK2                --------------------------------EYALNML---------------------
PLK1_Hsap_PLK1                --------------------------------RYARTMV---------------------
polo_Dmel_PLK1                --------------------------------RYAQEKL---------------------
SAK_Dmel_SAK                  --------------------------------RDRVGQI---------------------
PLK5_Mmus_PLK2                --------------------------------RHGLHL----------------------
PLK4_Mmus_SAK                 --------------------------------KQKLQCL---------------------
PLK3_Mmus_PLK2                --------------------------------RYALRLL---------------------
PLK2_Mmus_PLK2                --------------------------------EYALNML---------------------
PLK1_Mmus_PLK1                --------------------------------RYARTMV---------------------
plk-2_Cele_PLK1               --------------------------------QYAKCMI---------------------
plk-1_Cele_PLK1               --------------------------------KYAKTMI---------------------
F55G1.8_Cele_PLK1             --------------------------------EYAQAKI---------------------
CDC5_Scer_PLK1                --------------------------------REKLTLI---------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 --------------------------------KYIYGTL---------------------
8635_Tthe_SAK                 K------------------------------------------VNTKNGIIEISENNWLS
18358b_Tthe_PLK-Unclassified  --------------------------------TYTKDIL---------------------
18380_Tthe_PLK-Unclassified   --------------------------------KYTKQIL---------------------
21183_Tthe_SAK                --------------------------------GYAKQVI---------------------
22503_Tthe_PLK-Unclassified   --------------------------------LYIKDVF---------------------
5034_Tthe_SAK                 QNNNLKWNDRNNRRKRIHSSVNLKKHNDGDFSRWQRCHVDKVRRAFKQKTLQ--------
8829_Tthe_PLK-Unclassified    --------------------------------KYTKDIL---------------------
SAK_Spur_SAK                  --------------------------------REKLLHM---------------------
PLK1_Spur_PLK1                --------------------------------KYANNMV---------------------
PLK2_Spur_PLK2                --------------------------------SYARHVL---------------------
n1170_Tthe_PLK-Unclassified   --------------------------------RYTKEIL---------------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          --------------------------------KYCKEVL---------------------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             --------------------------------SERR------------------------
GK066_Glam_PLK-Unclassified   --------------------------------DRARKYY---------------------


PLK4_Hsap_SAK                 ---------------------SSI------------------------------------
PLK3_Hsap_PLK2                ---------------------R--------------------------------------
PLK2_Hsap_PLK2                ---------------------L--------------------------------------
PLK1_Hsap_PLK1                ---------------------DKL---LS----SRS------------------------
polo_Dmel_PLK1                ---------------------RKM---L--------------------------------
SAK_Dmel_SAK                  ---------------------PNIQLKLKTAPLLGS------------GRKTD-------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ---------------------SSI------------------------------------
PLK3_Mmus_PLK2                ---------------------R--------------------------------------
PLK2_Mmus_PLK2                ---------------------L--------------------------------------
PLK1_Mmus_PLK1                ---------------------DKL---LS----SRS------------------------
plk-2_Cele_PLK1               ---------------------QRL---VE----EHT------------KEETK-H-----
plk-1_Cele_PLK1               ---------------------ERL---MS----DAN------------VVSQNPA-----
F55G1.8_Cele_PLK1             ---------------------KLL---RP----TNN------------QEHVV-------
CDC5_Scer_PLK1                ---------------------KEG---LK-------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ---------------------SNN---LY----SKK------------PESSF-Q-----
8635_Tthe_SAK                 IECQNGQLIFKISPNGEQVVCQTL---KS----KTP------------L-VKIQNEKGTF
18358b_Tthe_PLK-Unclassified  ---------------------THM------------------------------------
18380_Tthe_PLK-Unclassified   ---------------------TDI---LK----QSQ------------PSQNNIN-----
21183_Tthe_SAK                ---------------------NAL---KT----KKV------------I-SKLENKEGIF
22503_Tthe_PLK-Unclassified   ---------------------LSG---NH----SKT------------QQANKLQGTDNQ
5034_Tthe_SAK                 ---------------------KNA---QD----KSA------------K-VKLENEDGQF
8829_Tthe_PLK-Unclassified    ---------------------THM---LN----NNT------------TNNNN-G-----
SAK_Spur_SAK                  ---------------------PHI------------------------------------
PLK1_Spur_PLK1                ---------------------KNM---LD----KKT------------T-----------
PLK2_Spur_PLK2                ---------------------YSM---MG----KGE------------------------
n1170_Tthe_PLK-Unclassified   ---------------------THL---LK----NNQ------------RQNTNDE-----
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ---------------------VSI---RS----ATS------------AGAGSGG-----
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ---------------------EII---KA----ARPVDSLAQYRYNKDS-----------


PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                ------------------------------------------------------------
PLK2_Hsap_PLK2                ------------------------------------------------------------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  --------------------------Y----N----------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                ------------------------------------------------------------
PLK2_Mmus_PLK2                ------------------------------------------------------------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ----NA-------------------PA---ANAVRLP-----------------------
plk-1_Cele_PLK1               ----RQ-------------------PDMPRSMAAARS-----------------------
F55G1.8_Cele_PLK1             --------------------------Y---VD----------------------------
CDC5_Scer_PLK1                ------------------------------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ----QLPQQQYQQPQHYQQQTQQPQPQ---PQ----------------------------
8635_Tthe_SAK                 MLMSNQPKQ------------------------------------N-----------YEV
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   ----NN-------------------PQ---NN----------------------------
21183_Tthe_SAK                ILLEN---N------------------------------------C-----------FEA
22503_Tthe_PLK-Unclassified   QNSGQ---N----PTKYSS--TT--PS---SNNQVQPSSV----PCSPPISSLTHSSS--
5034_Tthe_SAK                 YLYEN---K------------------------------------------------FEG
8829_Tthe_PLK-Unclassified    ----RG------------------------------------------------------
SAK_Spur_SAK                  ------------------------------------------------------------
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   ----QG------------------NNA---ANSVAPPDDMPQNEPN--------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ----GG------------------GG-E------RGTS----------------------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                ------------------------------------------------------------
PLK2_Hsap_PLK2                ------------------------------------------------------------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                ------------------------------------------------------------
PLK2_Mmus_PLK2                ------------------------------------------------------------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                ------------------------------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ------------------------------------------------------------
8635_Tthe_SAK                 SLSNGYKVSHVIGTDI-------MTVK---------------------------------
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   ------------------------------------------------------------
21183_Tthe_SAK                QFKTGYKIYYKNKNAS-------MKIK---------------------------------
22503_Tthe_PLK-Unclassified   --------------QNQKLTQAANNIVNPAQQMSASSLTQYQSVPLQNGQNQASMFNSTY
5034_Tthe_SAK                 VFSNGFIVNYKLNSQN-------LEIQ---------------------------------
8829_Tthe_PLK-Unclassified    ------------------------------------------------------------
SAK_Spur_SAK                  ------------------------------------------------------------
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   -----------------------------------------------------------Y
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          -------TE--------------RGEKERGGERAERG-----------------------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                ------------------------------------------------------------
PLK2_Hsap_PLK2                ------------------------------------------------------------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  ------------------------------------------------------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                ------------------------------------------------------------
PLK2_Mmus_PLK2                ------------------------------------------------------------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ------------------------------------------------------------
plk-1_Cele_PLK1               ------------------------------------------------------------
F55G1.8_Cele_PLK1             ------------------------------------------------------------
CDC5_Scer_PLK1                ------------------------------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ------------------------------------------------------------
8635_Tthe_SAK                 ------------------------------------------------------------
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   ------------------------------------------------------------
21183_Tthe_SAK                ------------------------------------------------------------
22503_Tthe_PLK-Unclassified   ----------QQGF------------------------------NQNNPQSSSLSPLNSI
5034_Tthe_SAK                 ------------------------------------------------------------
8829_Tthe_PLK-Unclassified    ------------------------------------------------------------
SAK_Spur_SAK                  ------------------------------------------------------------
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   NKYGMTATMENEQFPKLNEQKLKGMTSQKSLTEKDQLIYNMTGFNN--------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ------------------ERRMGG---------DDE------------------------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 ------------------------------------------------------------
PLK3_Hsap_PLK2                ------------------------------------------------------------
PLK2_Hsap_PLK2                ------------------------------------------------------------
PLK1_Hsap_PLK1                ------------------------------------------------------------
polo_Dmel_PLK1                ------------------------------------------------------------
SAK_Dmel_SAK                  ---------------------------------------------NAM------------
PLK5_Mmus_PLK2                ------------------------------------------------------------
PLK4_Mmus_SAK                 ------------------------------------------------------------
PLK3_Mmus_PLK2                ------------------------------------------------------------
PLK2_Mmus_PLK2                ------------------------------------------------------------
PLK1_Mmus_PLK1                ------------------------------------------------------------
plk-2_Cele_PLK1               ----------------------------------STSSN---------------------
plk-1_Cele_PLK1               ----------------------------------ASAGS---------------------
F55G1.8_Cele_PLK1             ---------------------------------------------SPC------------
CDC5_Scer_PLK1                ------------------------------------------------------------
zyg-1_Cele_SAK                ------------------------------------------------------------
PLK_Ddis_PLK1                 ---------------------------------------------QQQL-----------
8635_Tthe_SAK                 ---------------------DKQN-----------------------------KEFIVY
18358b_Tthe_PLK-Unclassified  ------------------------------------------------------------
18380_Tthe_PLK-Unclassified   ---------------------------------------------TQRQPM---------
21183_Tthe_SAK                ---------------------APDNNIY-------------------------------E
22503_Tthe_PLK-Unclassified   NQNISPVQQDPNNNISNNLQNNIQFSQIMKTNNNTTSSTNNSVSTSQQTPQQQVLNQIKY
5034_Tthe_SAK                 ---------------------TNKYAPKI------------------------------V
8829_Tthe_PLK-Unclassified    ------------------------------------------------------------
SAK_Spur_SAK                  ------------------------------------------------------------
PLK1_Spur_PLK1                ------------------------------------------------------------
PLK2_Spur_PLK2                ------------------------------------------------------------
n1170_Tthe_PLK-Unclassified   ---------------------------------------------GSK------------
n808_Tthe_PLK-Unclassified    ------------------------------------------------------------
CC1G_07437_Ccin_PLK1          ------------------------------RERD-----------R--ER----------
AqueK200_Aque_PLK1            ------------------------------------------------------------
AqueK201_Aque_SAK             ------------------------------------------------------------
GK066_Glam_PLK-Unclassified   ------------------------------------------------------------


PLK4_Hsap_SAK                 ---------------------------------------LL---MFSNPTPNFH
PLK3_Hsap_PLK2                -------------------------------------------------DRSPA
PLK2_Hsap_PLK2                --------------------------------------------------QRCN
PLK1_Hsap_PLK1                ----------------------------------------------ASNRLKAS
polo_Dmel_PLK1                -------------------------------------------------EKMFT
SAK_Dmel_SAK                  ---------------------------------------TPKT-TTPYYNRMLL
PLK5_Mmus_PLK2                --------------------------------------------------LQSV
PLK4_Mmus_SAK                 ---------------------------------------LL---MFSNPTPNFQ
PLK3_Mmus_PLK2                -------------------------------------------------DQSPA
PLK2_Mmus_PLK2                --------------------------------------------------QRCN
PLK1_Mmus_PLK1                ----------------------------------------------ASNRLKAS
plk-2_Cele_PLK1               ------------------------------VR-LESAA---DI-QPAYPSSSRR
plk-1_Cele_PLK1               ------------------------------RGPNQAASHLPQS-ASGSNIHPRR
F55G1.8_Cele_PLK1             ---------------RPTT-----------------SN-TAHG-APLASSRYLA
CDC5_Scer_PLK1                ---------------------------------------------QKSTIVTVD
zyg-1_Cele_SAK                ------------------------------------SE-MLHT-LCERMRKLHQ
PLK_Ddis_PLK1                 ----------------PQQLPQPQQSPAKQHQ--YQPNQIQYQQSIPQPQLINQ
8635_Tthe_SAK                 LSQQNLNKS------IPQEITLAVKVSLEQ-----MSSCLQK-Q-NEQYLANFK
18358b_Tthe_PLK-Unclassified  --------------------------------------------------LSGN
18380_Tthe_PLK-Unclassified   ---------------QPSSLSNQNNQNINT-----NG--ELLN-NSQKQNFVLK
21183_Tthe_SAK                ISLEKNSKD------FPQEVKNITS---KS-----LKY-YEYLL-NQNKEFQNI
22503_Tthe_PLK-Unclassified   NNSQQLSQTAKLSLYQSQKLRVSVENYQSP-----VSKPVQNAP-SVYPLKMYQ
5034_Tthe_SAK                 FDLQKDLKH------ASKEMK-------TI-----VQK-TQKII--SIITSMKS
8829_Tthe_PLK-Unclassified    --------------------------SMTN-----VN----PT-QNGTEKENYN
SAK_Spur_SAK                  ---------------------------------------IQ---LF-VNQNKPT
PLK1_Spur_PLK1                --------------------------------------------TTTAAAVPAH
PLK2_Spur_PLK2                ------------------------------------------------EDNEKL
n1170_Tthe_PLK-Unclassified   ---------------TPSQ---QKNPSVTA-----YPNAQQQP-AQLADKNQKK
n808_Tthe_PLK-Unclassified    -------------------------------------KSKVQ--SVKFKQNKKL
CC1G_07437_Ccin_PLK1          ---------ERA----DRGVERERLGSG--REAGS--S-TATL-NRRTSKLSMR
AqueK200_Aque_PLK1            --------------------------------------------LIVLSVAVSV
AqueK201_Aque_SAK             -----------------------------------------TT-ANSTMVSKCI
GK066_Glam_PLK-Unclassified   -----------------------------------TKKSASGS-STRQLGQGGE