TGFbR2_Hsap_STKR2 IELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPY--EEYASWKTEKDIFS--DIN-
TGFbR1_Hsap_STKR1 IVLQESIGKGRFGEVWRGKWRG------EEVAVKIFSS--REERSWFREAEIYQ--TVM-
MISR2_Hsap_STKR2 LCFSQVIREGGHAVVWAGQLQG------KLVAIKAFPP--RSVAQFQAERALYE--LPG-
MISR2_Mmus_STKR2 LRFSQVIQEGGHAVVWAGRLQG------EMVAIKAFPP--RAVAQFRAERAVYQ--LLG-
BMPR2_Mmus_STKR2 LKLLELIGRGRYGAVYKGSLD------ERPVAVKVFSF--ANRQNFINEKNIYR--VPL-
BMPR1B_Mmus_STKR1 IQMVKQIGKGRYGEVWMGKWRG------EKVAVKVFFT--TEEASWFRETEIYQ--TVL-
BMPR1A_Mmus_STKR1 IQMVRQVGKGRYGEVWMGKWRG------EKVAVKVFFT--TEEASWFRETEIYQ--TVL-
ALK7_Mmus_STKR1 IVLQEIVGKGRFGEVWHGRWCG------EDVAVKIFSS--RDERSWFREAEIYQ--TVM-
ALK4_Mmus_STKR1 IVLQEIIGKGRFGEVWRGRWRG------GDVAVKIFSS--REERSWFREAEIYQ--TVM-
ALK2_Mmus_STKR1 ITLLECVGKGRYGEVWRGSWQG------ENVAVKIFSS--RDEKSWFRETELYN--TVM-
ALK1_Mmus_STKR1 VALVECVGKGRYGEVWRGSWHG------ESVAVKIFSS--RDEQSWFRETEIYN--TVL-
ACTR2B_Mmus_STKR2 LQLLEIKARGRFGCVWKAQLMN------DFVAVKIFPL--QDKQSWQSEREIFS--TPG-
ACTR2_Mmus_STKR2 ----EVKARGRFGCVWKAQLLN------EYVAVKIFPI--QDKQSWQNEYEVYS--LPG-
daf-4_Cele_STKR2 ITDFQLISKGRFGKVFKAQYTPDS-GEKRLVAVKKLNE--FQKASFLAEKRIFD--ELNE
daf-1_Cele_STKR1 IRLTGRVGSGRFGNVSRGDYRG------EAVAVKVFNA--LDEPAFHKETEIFE--TRM-
BMPR1A_Hsap_STKR1 IQMVRQVGKGRYGEVWMGKWRG------EKVAVKVFFT--TEEASWFRETEIYQ--TVL-
BMPR1B_Hsap_STKR1 IQMVKQIGKGRYGEVWMGKWRG------EKVAVKVFFT--TEEASWFRETEIYQ--TVL-
BMPR2_Hsap_STKR2 LKLLELIGRGRYGAVYKGSLD------ERPVAVKVFSF--ANRQNFINEKNIYR--VPL-
ALK7_Hsap_STKR1 IVLQEIVGKGRFGEVWHGRWCG------EDVAVKIFSS--RDERSWFREAEIYQ--TVM-
ALK4_Hsap_STKR1 IVLQEIIGKGRFGEVWRGRWRG------GDVAVKIFSS--REERSWFREAEIYQ--TVM-
tkv_Dmel_STKR1 IQMVRLVGKGRYGEVWLAKWRD------ERVAVKTFFT--TEEASWFRETEIYQ--TVL-
put_Dmel_STKR2 IQLLEQKASGRFGDVWQAKLNN------QDVAVKIFRM--QEKESWTTEHDIYK--LPR-
SAX_Dmel_STKR1 VTLIECIGRGKYGEVWRGHWHG------ESIAVKIFFS--RDEESWKRETEIYS--TIL-
wit_Dmel_STKR2 MNLIGMLGSGKYGTVMKGLLH------DQEVAVKIYPE--EHHQYYVNERNIYA--LPL-
BABO_Dmel_STKR1 VQLCHVIGKGRFGEVWRGRWRG------ENVAVKIFSS--REECSWFREAEIYQ--TVM-
TGFBR1_Mmus_STKR1 IVLQESIGKGRFGEVWRGKWRG------EEVAVKIFSS--REERSWFREAEIYQ--TVM-
TGFBR2_Mmus_STKR2 IELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPY--EEYSSWKTEKDIFS--DIN-
sma-6_Cele_STKR1 LTIIKTIGQGRYGEVRKALYRG------SYVAVKTFYT--TDEDSWKNERDVYQ--TNM-
ALK2_Hsap_STKR1 ITLLECVGKGRYGEVWRGSWQG------ENVAVKIFSS--RDEKSWFRETELYN--TVM-
ALK1_Hsap_STKR1 VALVECVGKGRYGEVWRGLWHG------ESVAVKIFSS--RDEQSWFRETEIYN--TVL-
ACTR2B_Hsap_STKR2 LQLLEIKARGRFGCVWKAQLMN------DFVAVKIFPL--QDKQSWQSEREIFS--TPG-
ACTR2_Hsap_STKR2 ----EVKARGRFGCVWKAQLLN------EYVAVKIFPI--QDKQSWQNEYEVYS--LPG-
TGFbR1_Spur_STKR1 IVIQDCIGKGRYGEVYRGKWRG------ESVAVKIFSS--REERSWFREAEIYQ--TVM-
ALK2_Spur_STKR1 INLLQQVGKGRYGEVWMGTWQG------DTVAVKIFSS--IDEKSWFRETEIYN--TVM-
BMPR1_Spur_STKR1 VQLIRKIGKGRYGEVWKAKWRG------ENVAVKIYFT--AEEASWFRETDIYQ--TVL-
TGFbRII_Spur_STKR2 ITLDELIGKGRFGAVWRAHWKINNGTKERTVAVKVFLE--YDSASWNVEKELFTDHSVM-
ACTR2_Spur_STKR2 IQLLEIKARGRFGAVWKASCLN------DIVAVKVFPI--QDRNSWANEREIYS--LPH-
BMPR2_Spur_STKR2 LKMMELVGQGRYCNVYRAALS------ENEVAVKVFTG--SSKQCYMNELDIMG--LPH-
AqueK680_Aque_STKR1 ILLGESIGGGRFGQVYVGHYQG------ERYAVKKFFS--KDEQSWFHESDIYN--SVN-
AqueK681_Aque_STKR1 ITIHEHLGRGTYGSISRCTYRG------NTFAVKRFTT--INESSFRRELGIYS--F-S-
AqueK682_Aque_STKR1 VTKISVIGQGRFGKVWRCSYEE------KHIAMKVFKN--MHMAVFKREVEIYD--TYM-
AqueK683_Aque_STKR2 ------------------------------------------LSQWKIERDIYL--TPE-
AqueK684_Aque_STKR2 PEFMKIIGHGRFARVYHARMGT------RDVAIKIFNGTLQAKGSWTQEKDIYA--TER-
AqueK685_Aque_STKR2 FQLIQSIGNGRFGSVWKALYE------KETVAVRVFSQ--RHRTSWQNERDIHL--LNS-
AqueK686_Aque_STKR2 FQLLQPIGNGRFGSVWKALYN------NETVAVKALSL--HHKLSWQNERDIHL--LDS-
: * :
TGFbR2_Hsap_STKR2 --LKHENILQFLTAEERKT---ELGKQYWLITAFHAKGNLQEYLTR-HV-ISWEDLRKLG
TGFbR1_Hsap_STKR1 --LRHENILGFIAADNKDNG---TWTQLWLVSDYHEHGSLFDYLNR-YT-VTVEGMIKLA
MISR2_Hsap_STKR2 --LQHDHIVRFITASRGGPG--RLLSGPLLVLELHPKGSLCHYLTQ-YT-SDWGSSLRMA
MISR2_Mmus_STKR2 --LQHDHIVRFITAGQGGPG--PLPSGPLLVLELYPKGSLCHYLTQ-YT-SDWGSSLRMA
BMPR2_Mmus_STKR2 --MEHDNIARFIVGDERLTA--DGRMEYLLVMEYYPNGSLCKYLSL-HT-SDWVSSCRLA
BMPR1B_Mmus_STKR1 --MRHENILGFIAADIKGTG---SWTQLYLITDYHENGSLYDYLKS-TT-LDAKSMLKLA
BMPR1A_Mmus_STKR1 --MRHENILGFIAADIKGTG---SWTQLYLITDYHENGSLYDFLKC-AT-LDTRALLKLA
ALK7_Mmus_STKR1 --LRHENILGFIAADNKDNG---TWTQLWLVSEYHEQGSLYDYLNR-NI-VTVAGMVKLA
ALK4_Mmus_STKR1 --LRHENILGFIAADNKDNG---TWTQLWLVSDYHEHGSLFDYLNR-YT-VTIEGMIKLA
ALK2_Mmus_STKR1 --LRHENILGFIASDMTSRH---SSTQLWLITHYHEMGSLYDYLQL-TT-LDTVSCLRIV
ALK1_Mmus_STKR1 --LRHDNILGFIASDMTSRN---SSTQLWLITHYHEHGSLYDFLQR-QT-LEPQLALRLA
ACTR2B_Mmus_STKR2 --MKHENLLQFIAAEKRGSN---LEVELWLITAFHDKGSLTDYLKG-NI-ITWNELCHVA
ACTR2_Mmus_STKR2 --MKHENILQFIGAEKRGTS---VDVDLWLITAFHEKGSLSDFLKA-NV-VSWNELCHIA
daf-4_Cele_STKR2 YPKWYKSIVEFVCAEKIG-------DEYWIVTEFHERLSLYELLKN-NV-ISITSANRII
daf-1_Cele_STKR1 --LRHPNVLRYIGSDRVDT---GFVTELWLVTEYHPSGSLHDFLLE-NT-VNIETYYNLM
BMPR1A_Hsap_STKR1 --MRHENILGFIAADIKGTG---SWTQLYLITDYHENGSLYDFLKC-AT-LDTRALLKLA
BMPR1B_Hsap_STKR1 --MRHENILGFIAADIKGTG---SWTQLYLITDYHENGSLYDYLKS-TT-LDAKSMLKLA
BMPR2_Hsap_STKR2 --MEHDNIARFIVGDERVTA--DGRMEYLLVMEYYPNGSLCKYLSL-HT-SDWVSSCRLA
ALK7_Hsap_STKR1 --LRHENILGFIAADNKDNG---TWTQLWLVSEYHEQGSLYDYLNR-NI-VTVAGMIKLA
ALK4_Hsap_STKR1 --LRHENILGFIAADNKDNG---TWTQLWLVSDYHEHGSLFDYLNR-YT-VTIEGMIKLA
tkv_Dmel_STKR1 --MRHDNILGFIAADIKGNG---SWTQMLLITDYHEMGSLHDYLSM-SV-INPQKLQLLA
put_Dmel_STKR2 --MRHPNILEFLGVEKHM-----DKPEYWLISTYQHNGSLCDYLKS-HT-ISWPELCRIA
SAX_Dmel_STKR1 --LRHENILGFIGSDMTSRN---SCTQLWLMTHYYPLGSLFDHLNR-NA-LSHNDMVWIC
wit_Dmel_STKR2 --MECPALLSYFGYDERCTM--DGRMEYQLVLSLAPLGCLQDWLIA-NT-LTFSECCGML
BABO_Dmel_STKR1 --LRHENILGFIAADNKDNG---TWTQLWLVTDYHENGSLFDYLTT-HP-VDTNTMLNMS
TGFBR1_Mmus_STKR1 --LRHENILGFIAADNKDNG---TWTQLWLVSDYHEHGSLFDYLNR-YT-VTVEGMIKLA
TGFBR2_Mmus_STKR2 --LKHENILQFLTAEERKT---ELGKQYWLITAFHAKGNLQEYLTR-HV-ISWEDLRKLG
sma-6_Cele_STKR1 --INHENILQFVAADIWSEE--DSMTKMLLITDYHELGSLSDYLCREET-LTTDEALRLI
ALK2_Hsap_STKR1 --LRHENILGFIASDMTSRH---SSTQLWLITHYHEMGSLYDYLQL-TT-LDTVSCLRIV
ALK1_Hsap_STKR1 --LRHDNILGFIASDMTSRN---SSTQLWLITHYHEHGSLYDFLQR-QT-LEPHLALRLA
ACTR2B_Hsap_STKR2 --MKHENLLQFIAAEKRGSN---LEVELWLITAFHDKGSLTDYLKG-NI-ITWNELCHVA
ACTR2_Hsap_STKR2 --MKHENILQFIGAEKRGTS---VDVDLWLITAFHEKGSLSDFLKA-NV-VSWNELCHIA
TGFbR1_Spur_STKR1 --LRHENILGFIAADNKDNG---TWTQLILVSDYHENGSLFDYLNS-HV-IDVPGMLRMA
ALK2_Spur_STKR1 --LRHENILAFFASDMTSRQ---SCTQLWLIMEYHERGSLYDYLNR-HV-LDARQMCRLA
BMPR1_Spur_STKR1 --MRHTSILSFIAADIRGSG---AYTQLFLITEYHEWGSLYDFLNV-NI-LDSQSMLRLA
TGFbRII_Spur_STKR2 --MRHEHIVQFISAEVRRVSVTSPTRQYWLITKYYKNGSLHDYLRQ-RS-VNWIDLCKLC
ACTR2_Spur_STKR2 --MHHENLLHFIATEKHGEG---LEVEYWLISEFHHHGSLCDYLKA-NV-ISWKELCGIA
BMPR2_Spur_STKR2 --MEHSNLLQYVGSGDRMGE--DGWVEHLLVVDMISKGSLMSYLRE-NT-YDWHTMCRLA
AqueK680_Aque_STKR1 --LRHDNILTCFATDMLSNN---GVTELWLITQYHPRGSLFEELNR-GG-LTPETTLKFI
AqueK681_Aque_STKR1 --LTQTNILTYIAADMITID---GVMECWLILQYCPRGSLYMELTS-SP-PSLETGVRMV
AqueK682_Aque_STKR1 --LYHENILRFIGHDQIEF---ADTIELRLYTEYHENGTLQDYLKS-KPVFHFPECHQMA
AqueK683_Aque_STKR2 --LRHESILTLLRAKRVK-D--I---GYQLVLKGSITGSLYQYLQS-HS-PDELEAAKIT
AqueK684_Aque_STKR2 --LEHENILKFLYHDHRFHE---GQDTLWLIFDYHSNGSLYDYLQL-HR-LTFDELFSLC
AqueK685_Aque_STKR2 --TPHENILKFISSESRGR---GPSSEYFIITEYLPLGSLHQFLRH-NT-LSWEQAWNIM
AqueK686_Aque_STKR2 --TPHENILKFISSESRGR---GSSSEYFIITEYLPLGSLHQFLRH-NT-LSWEQAWNIM
: . : * * .
TGFbR2_Hsap_STKR2 SSLARGIAHLHSDHTP-C-G--RPKMPIVHRDLKSSNILVKN-DLTCCLCDFGLSLRLDP
TGFbR1_Hsap_STKR1 LSTASGLAHLHMEIVG-----TQGKPAIAHRDLKSKNILVKK-NGTCCIADLGLAVRHDS
MISR2_Hsap_STKR2 LSLAQGLAFLHEERWQ--N--GQYKPGIAHRDLSSQNVLIRE-DGSCAIGDLGLALVLPG
MISR2_Mmus_STKR2 LSLAEGLAFLHEERWQ--D--GQYKPGIAHRDLSSQNVLIRE-DRSCAIGDLGLALVLPG
BMPR2_Mmus_STKR2 HSVTRGLAYLHTELPRGD----HYKPAISHRDLNSRNVLVKN-DGACVISDFGLSMRLTG
BMPR1B_Mmus_STKR1 YSSVSGLCHLHTEIFS-----TQGKPAIAHRDLKSKNILVKK-NGTCCIADLGLAVKFIS
BMPR1A_Mmus_STKR1 YSAACGLCHLHTEIYG-----TQGKPAIAHRDLKSKNILIKK-NGSCCIADLGLAVKFNS
ALK7_Mmus_STKR1 LSIASGLAHLHMEIVG-----TQGKPAIAHRDIKSKNILVKK-CDTCAIADLGLAVKHDS
ALK4_Mmus_STKR1 LSAASGLAHLHMEIVG-----TQGKPGIAHRDLKSKNILVKK-NGMCAIADLGLAVRHDA
ALK2_Mmus_STKR1 LSIASGLAHLHIEIFG-----TQGKSAIAHRDLKSKNILVKK-NGQCCIADLGLAVMHSQ
ALK1_Mmus_STKR1 VSAACGLAHLHVEIFG-----TQGKPAIAHRDLKSRNVLVKS-NLQCCIADLGLAVMHSQ
ACTR2B_Mmus_STKR2 ETMSRGLSYLHEDVPW-CRG-EGHKPSIAHRDFKSKNVLLKS-DLTAVLADFGLAVRFEP
ACTR2_Mmus_STKR2 ETMARGLAYLHEDIPG-LK--DGHKPAISHRDIKSKNVLLKN-NLTACIADFGLALKFEA
daf-4_Cele_STKR2 MSMIDGLQFLHDDRPY-FFG-H-PKKPIIHRDIKSKNILVKS-DMTTCIADFGLARIYSY
daf-1_Cele_STKR1 RSTASGLAFLHNQIGG-SK--ESNKPAMAHRDIKSKNIMVKN-DLTCAIGDLGLSLSKPE
BMPR1A_Hsap_STKR1 YSAACGLCHLHTEIYG-----TQGKPAIAHRDLKSKNILIKK-NGSCCIADLGLAVKFNS
BMPR1B_Hsap_STKR1 YSSVSGLCHLHTEIFS-----TQGKPAIAHRDLKSKNILVKK-NGTCCIADLGLAVKFIS
BMPR2_Hsap_STKR2 HSVTRGLAYLHTELPRGD----HYKPAISHRDLNSRNVLVKN-DGTCVISDFGLSMRLTG
ALK7_Hsap_STKR1 LSIASGLAHLHMEIVG-----TQGKPAIAHRDIKSKNILVKK-CETCAIADLGLAVKHDS
ALK4_Hsap_STKR1 LSAASGLAHLHMEIVG-----TQGKPGIAHRDLKSKNILVKK-NGMCAIADLGLAVRHDA
tkv_Dmel_STKR1 FSLASGLAHLHDEIFG-----TPGKPAIAHRDIKSKNILVKR-NGQCAIADFGLAVKYNS
put_Dmel_STKR2 ESMANGLAHLHEEIPA-SKT-DGLKPSIAHRDFKSKNVLLKS-DLTACIADFGLAMIFQP
SAX_Dmel_STKR1 LSIANGLVHLHTEIFG-----KQGKPAMAHRDLKSKNILVTS-NGSCVIADFGLAVTHSH
wit_Dmel_STKR2 RSITRGISHLHTELRLGD----QHKPCVAHRDINTRNVLVQA-DLSCCIADFGFALKVFG
BABO_Dmel_STKR1 LSIATGLAHLHMDIVG-----TRGKPAIAHRDLKSKNILVKS-NLSCAIGDLGLAVRHVE
TGFBR1_Mmus_STKR1 LSTASGLAHLHMEIVG-----TQGKPAIAHRDLKSKNILVKK-NGTCCIADLGLAVRHDS
TGFBR2_Mmus_STKR2 SSLARGIAHLHSDHTP-C-G--RPKMPIVHRDLKSSNILVKN-DLTCCLCDFGLSLRLDP
sma-6_Cele_STKR1 HSCICGIEHLHAAVHG-TG--SFRKPEIAHRDIKSKNIIVKR-PNVCCIADLGLALRYQN
ALK2_Hsap_STKR1 LSIASGLAHLHIEIFG-----TQGKPAIAHRDLKSKNILVKK-NGQCCIADLGLAVMHSQ
ALK1_Hsap_STKR1 VSAACGLAHLHVEIFG-----TQGKPAIAHRDFKSRNVLVKS-NLQCCIADLGLAVMHSQ
ACTR2B_Hsap_STKR2 ETMSRGLSYLHEDVPW-CRG-EGHKPSIAHRDFKSKNVLLKS-DLTAVLADFGLAVRFEP
ACTR2_Hsap_STKR2 ETMARGLAYLHEDIPG-LK--DGHKPAISHRDIKSKNVLLKN-NLTACIADFGLALKFEA
TGFbR1_Spur_STKR1 LSIATGLAHLHMEIMG-----MQGKPAIAHRDIKSKNILVKR-NGQCAIADLGLAVRHDS
ALK2_Spur_STKR1 LTACSGLVHLHTEITC-----NNSKPAIAHRDIKTKNILVKR-NLTCCIADLGLAVLHTQ
BMPR1_Spur_STKR1 YSAANGLAHLHTEICG-----MQGKPAIAHRDVKSSNIMVRK-NGTCMIADMSLAARFLS
TGFbRII_Spur_STKR2 GSAARGLAHLHAETYG-SHG--LHKVPVAHRDLKSTNILVKD-DGSCAIADFGLAIRLDP
ACTR2_Spur_STKR2 FSMAKGLAYLHEDIPP-TTAIPFVKHSVAHRDFKSKNVLIKN-NTTACIADFGLACVFEA
BMPR2_Spur_STKR2 QTTAAGLAHLHQVIDTQV----GLKPAVVHRDINSRNVLVNA-EGNCVIGDFGFAMQVCG
AqueK680_Aque_STKR1 HSTCRGLAYLHLEITG-----TQGKPSVAHRDIKSKNILVKN-DSTCCIADFGLAVNYL-
AqueK681_Aque_STKR1 YSACMGLSYLHSSLQG-YG--PIAKPRIAHRDIKSKNILMKT-AETCCIADFGLSIADSE
AqueK682_Aque_STKR1 VSLSSGLTYLHKTIVA-G----KIKPGIAHRDLKSSNILVKT-DYTLCIADLGLAIKQSE
AqueK683_Aque_STKR2 HSMSSGLAHLHYMESSQSHSK-YRVITIAHCNINSHNILMKE-DGTVFLSD---------
AqueK684_Aque_STKR2 LSGAAGLEHLHSVDNC---P-ETYKPAIAHRDLKSKNILVKK-DMTCCISDFGLAIKFDG
AqueK685_Aque_STKR2 YSITSGITHLHSSSYYS-NGLLADKFSIAHRDIKPSNILVKSPSGQCVVADFGQAFVLDP
AqueK686_Aque_STKR2 YSIASGITHLHSNSYYNSNGLLLEKYSIAHRDIKPSNILVKSVSGHCVVADLGLAFILDP
: *: .** : * :... *::: : *
TGFbR2_Hsap_STKR2 TL-------SVDD--------LANSGQVGTARYMAPEVLESRMNLENVE-SFKQTDVYSM
TGFbR1_Hsap_STKR1 AT-------DTID--------IAPNHRVGTKRYMAPEVLDDSINMKHF-ESFKRADIYAM
MISR2_Hsap_STKR2 LT-------QPPAWTPTQPQGPAAIMEAGTQRYMAPELLDKTLDLQDWGMALRRADIYSL
MISR2_Mmus_STKR2 LA-------QPPALAPTQPRGPAAILEAGTQRYMAPELLDKTLDLQDWGTALQRADVYSL
BMPR2_Mmus_STKR2 NRLV---RPGEED--------NAAISEVGTIRYMAPEVLEGAVNLRDCESALKQVDMYAL
BMPR1B_Mmus_STKR1 DT-------NEVD--------IPPNTRVGTKRYMPPEVLDESLNRNHF-QSYIMADMYSF
BMPR1A_Mmus_STKR1 DT-------NEVD--------IPLNTRVGTKRYMAPEVLDESLNKNHF-QPYIMADIYSF
ALK7_Mmus_STKR1 IM-------NTID--------IPQNPKVGTKRYMAPEMLDDTMNLSIF-ESFKRADIYSV
ALK4_Mmus_STKR1 VT-------DTID--------IAPNQRVGTKRYMAPEVLDETINMKHF-DSFKCADIYAL
ALK2_Mmus_STKR1 ST-------NQLD--------VGNNPRVGTKRYMAPEVLDETIQVDCF-DSYKRVDIWAF
ALK1_Mmus_STKR1 SS-------DYLD--------IGNNPRVGTKRYMAPEVLDEHIRTDCF-ESYKWTDIWAF
ACTR2B_Mmus_STKR2 GK-------PP----------GDTHGQVGTRRYMAPEVLEGAINFQR--DAFLRIDMYAM
ACTR2_Mmus_STKR2 GK-------SA----------GDTHGQVGTRRYMAPEVLEGAINFQR--DAFLRIDMYAM
daf-4_Cele_STKR2 DI-------EQ----------SDLLGQVGTKRYMSPEMLEGATEFTP--TAFKAMDVYSM
daf-1_Cele_STKR1 DA-------ASDII-------ANENYKCGTVRYLAPEILNSTMQFTVF-ESYQCADVYSF
BMPR1A_Hsap_STKR1 DT-------NEVD--------VPLNTRVGTKRYMAPEVLDESLNKNHF-QPYIMADIYSF
BMPR1B_Hsap_STKR1 DT-------NEVD--------IPPNTRVGTKRYMPPEVLDESLNRNHF-QSYIMADMYSF
BMPR2_Hsap_STKR2 NRLV---RPGEED--------NAAISEVGTIRYMAPEVLEGAVNLRDCESALKQVDMYAL
ALK7_Hsap_STKR1 IL-------NTID--------IPQNPKVGTKRYMAPEMLDDTMNVNIF-ESFKRADIYSV
ALK4_Hsap_STKR1 VT-------DTID--------IAPNQRVGTKRYMAPEVLDETINMKHF-DSFKCADIYAL
tkv_Dmel_STKR1 EL-------DVIH--------IAQNPRVGTRRYMAPEVLSQQLDPKQF-EEFKRADMYSV
put_Dmel_STKR2 GK-------PC----------GDTHGQVGTRRYMAPEVLEGAINFNR--DAFLRIDVYAC
SAX_Dmel_STKR1 VT-------GQLD--------LGNNPKVGTKRYMAPEVLDESIDLECF-EALRRTDIYAF
wit_Dmel_STKR2 SKYEYKGEVAMAE--------TKSINEVGTLRYMAPELLEGAVNLRDCETSLKQMDVYAL
BABO_Dmel_STKR1 KN-------DSVD--------IPSTHRVGTKRYMAPEVLDESMNDQHF-DSYKRADVYAF
TGFBR1_Mmus_STKR1 AT-------DTID--------IAPNHRVGTKRYMAPEVLDDSINMKHF-ESFKRADIYAM
TGFBR2_Mmus_STKR2 TL-------SVDD--------LANSGQVGTARYMAPEVLESRMNLENVE-SFKQTDVYSM
sma-6_Cele_STKR1 DK--------ILP--------EKFNVQVGTKRYMAPELISNKLNPKDF-SQFKMADIYSM
ALK2_Hsap_STKR1 ST-------NQLD--------VGNNPRVGTKRYMAPEVLDETIQVDCF-DSYKRVDIWAF
ALK1_Hsap_STKR1 GS-------DYLD--------IGNNPRVGTKRYMAPEVLDEQIRTDCF-ESYKWTDIWAF
ACTR2B_Hsap_STKR2 GK-------PP----------GDTHGQVGTRRYMAPEVLEGAINFQR--DAFLRIDMYAM
ACTR2_Hsap_STKR2 GK-------SA----------GDTHGQVGTRRYMAPEVLEGAINFQR--DAFLRIDMYAM
TGFbR1_Spur_STKR1 VT-------DTVD--------IFPNNRIGTKRYMAPEVLDDTINMNHF-DSFKRADVYSF
ALK2_Spur_STKR1 RE-------DNID--------MGTNTRVGTKRYMAPELLEETMDVRCF-ESFKRVDVYAF
BMPR1_Spur_STKR1 EG-------NEID--------LGQNTRLGTTRYLPPEVLDNVLMSNTF-DAFKMADMYSF
TGFbRII_Spur_STKR2 QS-------STDH--------LANSGQVGTPRYMSPEALECKVNLQDIE-SFKQMDTYAL
ACTR2_Spur_STKR2 GK-------NP----------GDTHGQVGTRRYMAPEVLEGAIQFKR--DAFLRIDMYAF
BMPR2_Spur_STKR2 SSVV---GEGDGD--------NSTITDVGTVRYMSPEVLDGAVNLRDCECALKQVDVYAL
AqueK680_Aque_STKR1 ------------N--------FNNNVQQGTKRYMPPEVIKGTIDVHSF-ESFLRADIYSF
AqueK681_Aque_STKR1 D----------FQ--------SFICLKQGTNRYMAPEILNETIDVKDF-VSFLRADVYSF
AqueK682_Aque_STKR1 SG-------DGVDQ-------IPANKLSGTKRYMSPEILNESLDYGRF-ICYAQSDIYSF
AqueK683_Aque_STKR2 ------------------------------------------------------------
AqueK684_Aque_STKR2 VD-------MI-L--------SEAKGQVGTSRYMAPEILEGAVRFNQ--EAFLKIDIYAF
AqueK685_Aque_STKR2 AA-------DDRK--------LAVSGQVGTYRYMSPEALDARVNLRDSE-SFKQIDVYAM
AqueK686_Aque_STKR2 AA-------DDRK--------LAVSGQVGTYRYMSPEALDARVNLRDIE-SFKQIDMYAL
TGFbR2_Hsap_STKR2 ALVLWEMTSRCNAV----------------------------------------------
TGFbR1_Hsap_STKR1 GLVFWEIARRCSIG----------------------------------------------
MISR2_Hsap_STKR2 ALLLWEILSRCPDLRPDS------------------------------------------
MISR2_Mmus_STKR2 ALLLWEILSRCSDLRPDH------------------------------------------
BMPR2_Mmus_STKR2 GLIYWEVFMRCTDL-F-------------------------------------------P
BMPR1B_Mmus_STKR1 GLILWEIARRCVSG----------------------------------------------
BMPR1A_Mmus_STKR1 GLIIWEMARRCITG----------------------------------------------
ALK7_Mmus_STKR1 GLVYWEIARRCSVG----------------------------------------------
ALK4_Mmus_STKR1 GLVYWEIARRCNSG----------------------------------------------
ALK2_Mmus_STKR1 GLVLWEVARRMVSN----------------------------------------------
ALK1_Mmus_STKR1 GLVLWEIARRTIIN----------------------------------------------
ACTR2B_Mmus_STKR2 GLVLWELVSRCKAA----------------------------------------------
ACTR2_Mmus_STKR2 GLVLWELASRCTAA----------------------------------------------
daf-4_Cele_STKR2 GLVMWEVISRTKLHQ---------------------------------------------
daf-1_Cele_STKR1 SLVMWETLCRCEDGDVLP------------------------------------------
BMPR1A_Hsap_STKR1 GLIIWEMARRCITG----------------------------------------------
BMPR1B_Hsap_STKR1 GLILWEVARRCVSG----------------------------------------------
BMPR2_Hsap_STKR2 GLIYWEIFMRCTDL-F-------------------------------------------P
ALK7_Hsap_STKR1 GLVYWEIARRCSVG----------------------------------------------
ALK4_Hsap_STKR1 GLVYWEIARRCNSG----------------------------------------------
tkv_Dmel_STKR1 GLVLWEMTRRCYTPVSGT-----------------------------------------K
put_Dmel_STKR2 GLVLWEMVSRCDF-----------------------------------------------
SAX_Dmel_STKR1 GLVLWEVCRRTISC----------------------------------------------
wit_Dmel_STKR2 GLVLWEVATRCSDFYA-------------------------------------------P
BABO_Dmel_STKR1 GLILWEIARRCNMG----------------------------------------------
TGFBR1_Mmus_STKR1 GLVFWEIARRCSIG----------------------------------------------
TGFBR2_Mmus_STKR2 ALVLWEMTSRCNAV----------------------------------------------
sma-6_Cele_STKR1 ALVMWEVAIRVEVNTCEEVLTVDETSPDHSASSGIGESVSSSGNISRMHLQKTNVEGHST
ALK2_Hsap_STKR1 GLVLWEVARRMVSN----------------------------------------------
ALK1_Hsap_STKR1 GLVLWEIARRTIVN----------------------------------------------
ACTR2B_Hsap_STKR2 GLVLWELVSRCKAA----------------------------------------------
ACTR2_Hsap_STKR2 GLVLWELASRCTAA----------------------------------------------
TGFbR1_Spur_STKR1 GLVLWEIGRRCQVF----------------------------------------------
ALK2_Spur_STKR1 GLVMWEIARRCEVG----------------------------------------------
BMPR1_Spur_STKR1 GMVLWEIARR--------------------------------------------------
TGFbRII_Spur_STKR2 ALILWEITSRCTLL----------------------------------------------
ACTR2_Spur_STKR2 GLVLWELVTRCTVQ----------------------------------------------
BMPR2_Spur_STKR2 GLVVWEIAMRCKDL-Y-------------------------------------------P
AqueK680_Aque_STKR1 GLVMWEVCTRCHLE----------------------------------------------
AqueK681_Aque_STKR1 ALVAWEVFNRCNIEQG--------------------------------------------
AqueK682_Aque_STKR1 SLIIWEIFNCCEIDGVPR------------------------------------------
AqueK683_Aque_STKR2 ------------------------------------------------------------
AqueK684_Aque_STKR2 GLILWEM-----------------------------------------------------
AqueK685_Aque_STKR2 SLVLWEVCMRYQSN----------------------------------------------
AqueK686_Aque_STKR2 SLVLWEVCMRYQSD----------------------------------------------
TGFbR2_Hsap_STKR2 G-EVKDYEPPFGSKVRE-HPCVESMKDNVLRDRGRPEIPSFWLNH-QGIQMVCETLTECW
TGFbR1_Hsap_STKR1 -GIHEDYQLPYYDLVPS-DPSVEEMRKVVCEQKLRPNIPNRWQSCE-ALRVMAKIMRECW
MISR2_Hsap_STKR2 --SPPPFQLAYEAELGN-TPTSDELWALAVQERRRPYIPSTWRCFATDPDGLRELLEDCW
MISR2_Mmus_STKR2 --RPPPFQLAYEAELGS-NPSACELWALAVEERKRPNIPSTWSCSATDPRGLRELLEDCW
BMPR2_Mmus_STKR2 GESVPDYQMAFQTEVGN-HPTFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCW
BMPR1B_Mmus_STKR1 -GIVEEYQLPYHDLVPS-DPSYEDMREIVCMKKLRPSFPNRWSSDE-CLRQMGKLMTECW
BMPR1A_Mmus_STKR1 -GIVEEYQLPYYNMVPS-DPSYEDMREVVCVKRLRPIVSNRWNSDE-CLRAVLKLMSECW
ALK7_Mmus_STKR1 -GVVEEYQLPYYDMVPS-DPSIEEMRKVVCDQKLRPNLPNQWQSCE-ALRVMGRIMRECW
ALK4_Mmus_STKR1 -GVHEDYQLPYYDLVPS-DPSIEEMRKVVCDQKLRPNVPNWWQSYE-ALRVMGKMMRECW
ALK2_Mmus_STKR1 -GIVEDYKPPFYDVVPN-DPSFEDMRKVVCVDQQRPNIPNRWFSDP-TLTSLAKLMKECW
ALK1_Mmus_STKR1 -GIVEDYRPPFYDMVPN-DPSFEDMKKVVCVDQQTPTIPNRLAADP-VLSGLAQMMRECW
ACTR2B_Mmus_STKR2 DGPVDEYMLPFEEEIGQ-HPSLEELQEVVVHKKMRPTIKDHWLKHP-GLAQLCVTIEECW
ACTR2_Mmus_STKR2 DGPVDEYMLPFEEEIGQ-HPSLEDMQEVVVHKKKRPVLRDYWQKHA-GMAMLCETIEECW
daf-4_Cele_STKR2 TDEPPNYQMPFQ-VIGF-DPTIGLMRNYVVSKKERPQWRDEIIKH---------------
daf-1_Cele_STKR1 --REAATVIPYIEWTDR-DPQDAQMFDVVCTRRLRPTENPLWKDHP-EM-----------
BMPR1A_Hsap_STKR1 -GIVEEYQLPYYNMVPS-DPSYEDMREVVCVKRLRPIVSNRWNSDE-CLRAVLKLMSECW
BMPR1B_Hsap_STKR1 -GIVEEYQLPYHDLVPS-DPSYEDMREIVCIKKLRPSFPNRWSSDE-CLRQMGKLMTECW
BMPR2_Hsap_STKR2 GESVPEYQMAFQTEVGN-HPTFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCW
ALK7_Hsap_STKR1 -GIVEEYQLPYYDMVPS-DPSIEEMRKVVCDQKFRPSIPNQWQSCE-ALRVMGRIMRECW
ALK4_Hsap_STKR1 -GVHEEYQLPYYDLVPS-DPSIEEMRKVVCDQKLRPNIPNWWQSYE-ALRVMGKMMRECW
tkv_Dmel_STKR1 TTTCEDYALPYHDVVPS-DPTFEDMHAVVCVKGFRPPIPSRWQEDD-VLATVSKIMQECW
put_Dmel_STKR2 AGPVGEFQLPFEAELGL-RPSLDEVQESVVMKKLRPRLLNSWRAHP-GLNVFCDTMEECW
SAX_Dmel_STKR1 -GIAEEYKVPFYDVVPM-DPSFEDMRKVVCIDNYRPSIPNRWSSDS-LMTGMSKLMKECW
wit_Dmel_STKR2 GQATPPYKAPYEQEVGS-HPSFDQMQALVVRHKARPLFPTGWGGG-AAAKVVRDTCEDCW
BABO_Dmel_STKR1 -MIYDEYQLPYYDVVQP-DPSIEEMKKVVCIEKCRPNIPNRWHASD-VLHNMAKVMKECW
TGFBR1_Mmus_STKR1 -GIHEDYQLPYYDLVPS-DPSVEEMRKVVCEQKLRPNIPNRWQSCE-ALRVMAKIMRECW
TGFBR2_Mmus_STKR2 G-EVKDYEPPFGSKVRE-HPCVESMKDSVLRDRGRPEIPSFWLNH-QGIQIVCETLTECW
sma-6_Cele_STKR1 SLKAKQHVPPFDGIVHN-DPNFDEMNDVICVRRIRPPPDLAWKNVP-ALNELSKLMEDSW
ALK2_Hsap_STKR1 -GIVEDYKPPFYDVVPN-DPSFEDMRKVVCVDQQRPNIPNRWFSDP-TLTSLAKLMKECW
ALK1_Hsap_STKR1 -GIVEDYRPPFYDVVPN-DPSFEDMKKVVCVDQQTPTIPNRLAADP-VLSGLAQMMRECW
ACTR2B_Hsap_STKR2 DGPVDEYMLPFEEEIGQ-HPSLEELQEVVVHKKMRPTIKDHWLKHP-GLAQLCVTIEECW
ACTR2_Hsap_STKR2 DGPVDEYMLPFEEEIGQ-HPSLEDMQEVVVHKKKRPVLRDYWQKHA-GMAMLCETIEECW
TGFbR1_Spur_STKR1 -GIYEEFCLPYHPWVPM-DPPIDDMRRIVCIEKRRPPVPNRWNSHK-IMESYAKVMKECW
ALK2_Spur_STKR1 -GMVADYKPPFFEYVPS-DPSFDDMRKVACIEKLRPNIPNRWTNNT-VLTSMAKLMKECW
BMPR1_Spur_STKR1 ------------------------------------------------------------
TGFbRII_Spur_STKR2 K-DINEYELPFSRSLGDRRASLEMMKTLVVLRRERPPITDEWLRN-PGLTIIKNTVVDCW
ACTR2_Spur_STKR2 DGPVPEYRLPFEEELGQ-GTSLEDMQEWVVVKRKRPVISDHWLKHR-GLELLCETIEECW
BMPR2_Spur_STKR2 RDEMGNYQMPFEEQVGL-HPTFEDMQILVSRERKRPQFPDAWKQNSQALRSLKETIEDCW
AqueK680_Aque_STKR1 -GPLADYALPFQSQVPP-DPTLDDMTEFIVGKEVIPEIPETWSNNE-LLRGMSRVMYECW
AqueK681_Aque_STKR1 -GIAREYQLPYSDHLPN-NSSIEDCRRVVVEEGTRPV-TSEWSKTR-FLEKLSVTIKELW
AqueK682_Aque_STKR1 -----SYQLPYCEWVPT-DPDIDQMKQCVCVNNRRPTIPDSWTESE-TLSPIAKLLDSSW
AqueK683_Aque_STKR2 ------------------------------------------------------------
AqueK684_Aque_STKR2 ------------------------------------------------------------
AqueK685_Aque_STKR2 DVPVPPYQSPFFDMVGE-KPTLDQMKEIVVINKQRPLLPEKWNND-KNLKRIIKLIVEGW
AqueK686_Aque_STKR2 DVPVPPYQSPFFDMVGE-KPTLEQMKEIVVNANKRPGFTGVWYSD-KNLKRIIKLIKEGW
TGFbR2_Hsap_STKR2 DHDPEARLTAQCVAER--FS
TGFbR1_Hsap_STKR1 YANGAARLTALRI-KK--TL
MISR2_Hsap_STKR2 DADPEARLTAECV-QQ--RL
MISR2_Mmus_STKR2 DADPEARLTAECV-QQ--RL
BMPR2_Mmus_STKR2 DQDAEARLTAQCAE-E--RM
BMPR1B_Mmus_STKR1 AQNPASRLTALRV-KK--TL
BMPR1A_Mmus_STKR1 AHNPASRLTALRI-KK--TL
ALK7_Mmus_STKR1 YANGAARLTALRV-KK--TI
ALK4_Mmus_STKR1 YANGAARLTALRI-KK--TL
ALK2_Mmus_STKR1 YQNPSARLTALRI-KK--TL
ALK1_Mmus_STKR1 YPNPSARLTALRI-KK--TL
ACTR2B_Mmus_STKR2 DHDAEARLSAGCV-EE--RV
ACTR2_Mmus_STKR2 DHDAEARLSAGCV-GE--RI
daf-4_Cele_STKR2 ---------------E--YM
daf-1_Cele_STKR1 ------------------KH
BMPR1A_Hsap_STKR1 AHNPASRLTALRI-KK--TL
BMPR1B_Hsap_STKR1 AHNPASRLTALRV-KK--TL
BMPR2_Hsap_STKR2 DQDAEARLTAQCAE-E--RM
ALK7_Hsap_STKR1 YANGAARLTALRI-KK--TI
ALK4_Hsap_STKR1 YANGAARLTALRI-KK--TL
tkv_Dmel_STKR1 HPNPTVRLTALRV-KK--TL
put_Dmel_STKR2 DHDAEARLSSSCV------M
SAX_Dmel_STKR1 HQNPDVRLPALRI-KK--TI
wit_Dmel_STKR2 DHDADARLTS---------L
BABO_Dmel_STKR1 YPNPVARLTALRI-KK--TL
TGFBR1_Mmus_STKR1 YANGAARLTALRI-KK--TL
TGFBR2_Mmus_STKR2 DHDPEARLTAQCVAER--FS
sma-6_Cele_STKR1 HSIPHFRHSALKL-KKEMAE
ALK2_Hsap_STKR1 YQNPSARLTALRI-KK--TL
ALK1_Hsap_STKR1 YPNPSARLTALRI-KK--TL
ACTR2B_Hsap_STKR2 DHDAEARLSAGCV-EE--RV
ACTR2_Hsap_STKR2 DHDAEARLSAGCV-GE--RI
TGFbR1_Spur_STKR1 YQNGAARLTALRI-KK--TL
ALK2_Spur_STKR1 CPTASARHTSLRV-KK--TL
BMPR1_Spur_STKR1 -------------------C
TGFbRII_Spur_STKR2 DEDPEARLT----------A
ACTR2_Spur_STKR2 DQDAEARLS----------A
BMPR2_Spur_STKR2 DHDAEARLT----------A
AqueK680_Aque_STKR1 YHQPTARPSAYYI-RK---K
AqueK681_Aque_STKR1 AERGSERPSIELLRKK--IE
AqueK682_Aque_STKR1 ATQASSRISALRI-S---KI
AqueK683_Aque_STKR2 -------------------F
AqueK684_Aque_STKR2 -------------------L
AqueK685_Aque_STKR2 DEDPEARLTAANIK-I--QL
AqueK686_Aque_STKR2 DEDPEARLTAANIK-I--QL