Protein (view, download) , Domain
TIF1g_Hsap      MAENKGGGEAES------------------GGGGSGSAPVTAGA----------------
TIF1b_Hsap      MAASAAAA----------------------------------------------------
TIF1a_Hsap      MEVAVEKA----------------------------------------------------
TIF1_Spur       MSSSRRSMYSISVLALVFVVGPGVIKLPGAGAGMCGCPPLWTGFNDNCYRFFVSGNLSWF
bon_Dmel        MDMDLEQLKN--------------------------------------------------
TIF1a_Mmus      MEVAVEKA----------------------------------------------------
TIF1b_Mmus      MAASAAAT----------------------------------------------------
TIF1g_Mmus      MAENKGGGEAES------------------GGGGSGSAPVTAGA----------------
TIF1D_Hsap      MA----------------------------------------------------------
TIF1D_Mmus      MA----------------------------------------------------------
                *

TIF1g_Hsap      ---------AGPAAQEAEP----PLTAVLVEEEEEEGGRA--------------------
TIF1b_Hsap      ------------------------------------------------------------
TIF1a_Hsap      ------------------------------------------------------------
TIF1_Spur       DAELACRTFSTPCGEESSSSSMGHLVSIHSQEEMD-FITAMYDSLRSKRPTIDTRTWIGL
bon_Dmel        -------------------D-FLPLIAGIKQEQLD-A-----------------------
TIF1a_Mmus      ------------------------------------------------------------
TIF1b_Mmus      ------------------------------------------------------------
TIF1g_Mmus      ---------AGPTAQEAEP----PLAAVLVEEEEEEGGRA--------------------
TIF1D_Hsap      ------------------------------------------------------------
TIF1D_Mmus      ------------------------------------------------------------


TIF1g_Hsap      ---GAEGGAAGPDDGGVAAASSGS-AQAAS----------------------SPAASVGT
TIF1b_Hsap      ------------------SA---A-AASAA----------------------SGSPGPGE
TIF1a_Hsap      ------------------VAAAAA-ASAAA----------------------SGGP----
TIF1_Spur       HDRTAEQSAEWTDSSDFDYASWAPSQPNDQNGASDCVFFSRNTLYKWNDIPCTPGSRVES
bon_Dmel        ----------VP----TDALPQMS-TPNTA----------------------SGAPTTSS
TIF1a_Mmus      ------------------AAAAAP-A---------------------------GGPA---
TIF1b_Mmus      -----------------AAASAAT-AASAA----------------------SGSPGSGE
TIF1g_Mmus      ---GAEGGAAGPDDGGVAAASSSS-APAAS----------------------VPAASVGS
TIF1D_Hsap      ------------------------------------------------------------
TIF1D_Mmus      ------------------------------------------------------------


TIF1g_Hsap      GVAGGAVSTPAP--------------APASAPAPGPSAGPPPGPPASLLDTCAVCQQSLQ
TIF1b_Hsap      GSAGGEKRSTAP----SAA------ASASASAAASSPAG-GGAEALELLEHCGVCRERLR
TIF1a_Hsap      --------SAAP----SGE------NEAESRQGPDSERG-GEAARLNLLDTCAVCHQNIQ
TIF1_Spur       ----------------FVS------DSITSETMEASTSG-QGTSNIHLDLKCKVCEREFS
bon_Dmel        LS------SSSL----SLS------NPC-DSAEKRSESN-SSASAKFTLFKCVYCAQLLG
TIF1a_Mmus      --------AAAP----SGE------NEAESRQGPDSESG-GEASRLNLLDTCAVCHQNIQ
TIF1b_Mmus      GSAGGEKR---P----AAS------SAAAASAAASSPAG-GGGEAQELLEHCGVCRERLR
TIF1g_Mmus      AVPGGAASTPAPAAAPAPAPAPAPAPAPAPAPAPGSSSGPPLGPPASLLDTCAVCQQSLQ
TIF1D_Hsap      ------------------------------------------------------------
TIF1D_Mmus      ------------------------------------------------------------


TIF1g_Hsap      SRREAEPKLLPCLHSFCLRCLPEPERQLSVPI----------------------PGGSNG
TIF1b_Hsap      P--EREPRLLPCLHSACSACLGPAAPAAA------------------------NSSGDGG
TIF1a_Hsap      SR---APKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPP--VPA--PGSPVSGSSP
TIF1_Spur       A--DVQPRMLPCLHTVCAQCLANVTNNTAL------------------------ASGQQG
bon_Dmel        S--NDRPKLLECLHVACAQCVSTKFSELDRSL----------------------------
TIF1a_Mmus      SR---VPKLLPCLHSFCQRCLPAPQRYLMLTAPALGSAETPPPAPAPAPAPGSPAGGPSP
TIF1b_Mmus      P--ERDPRLLPCLHSACSACLGPATPAAA------------------------NNSGDGG
TIF1g_Mmus      SRREAEPKLLPCLHSFCLRCLPEPERQLSVPI----------------------PGGSNG
TIF1D_Hsap      ------------------------------------------------------------
TIF1D_Mmus      ------------------------------------------------------------


TIF1g_Hsap      DIQQ--VGVIRCPVCRQECRQI-DLVDNYFVKDTSEAPSS---------------SDEKS
TIF1b_Hsap      AAGD--GTVVDCPVCKQQCFSK-DIVENYFMRDSGSKAAT---------------DAQDA
TIF1a_Hsap      FATQ--VGVIRCPVCSQECAER-HIIDNFFVKDTTEVPSS---------------TVEKS
TIF1_Spur       ILAGSGVVIAKCPICKDDIRSLDDIVEDTWTVPMATA--H---------------SMSGG
bon_Dmel        ------PPLIHCPVCDNASQQE-FIVDNQFLIEQCTAGDSGDGVGLLGLTGEGQKSSAAA
TIF1a_Mmus      FATQ--VGVIRCPVCSQECAER-HIIDNFFVKDTTEVPSS---------------TVEKS
TIF1b_Mmus      SAGD--GAMVDCPVCKQQCYSK-DIVENYFMRDSGSKASS---------------DSQDA
TIF1g_Mmus      DVQQ--VGVIRCPVCRQECRQI-DLVDNYFVKDTSEAPSS---------------SDEKS
TIF1D_Hsap      ------------------------------------------------------------
TIF1D_Mmus      ------------------------------------------------------------


TIF1g_Hsap      EQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVS-ES-VGASG-
TIF1b_Hsap      NQCCTSCEDNAPATSYCVECSEPLCETCVEAHQRVKYTKDHTVRSTGP----A-KSRDG-
TIF1a_Hsap      NQVCTSCEDNAEANGFCVECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEA-VGVTS-
TIF1_Spur       EMLCHNCDANAPATNFCVDCPGGLCDPCVLLHGKVRFLRDHVIQPRSEEN----TVSHI-
bon_Dmel        SIQCSSCSDGAVATSWCVDCSEYICDSCVQAHQRLKITKDHTIKPKDEANNEQLAGAAGV
TIF1a_Mmus      NQVCTSCEDNAEANGFCVECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEA-VGVTS-
TIF1b_Mmus      NQCCTSCEDNAPATSYCVECSEPLCETCVEAHQRVKYTKDHTVRSTGP----A-KTRDG-
TIF1g_Mmus      EQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVS-ES-VGTSG-
TIF1D_Hsap      -RNCSECKEKRAAHILCTYCNRWLCSSCTEEHRHSPVPGGPFFPRAQKGSPGV-NGGPG-
TIF1D_Mmus      -RNCSECKEKRAAHILCTYCNRWLCSSCTEEHRHVPAPGGPLFARAQKGSSGV-NGGSG-
                   * .*.    *   *. *   :*..*   * :     .  .

TIF1g_Hsap      QRPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKL
TIF1b_Hsap      ERTVYCNVHKHEPLVLFCESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRKLLASLVKRL
TIF1a_Hsap      QRPVFCPFHKKEQLKLYCETCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKL
TIF1_Spur       VQPPFCTIHPKERLQLYCEKCVRLTCRDCQLVSHKDHSYQFLTEAAASQRLTMRRFIQEL
bon_Dmel        DKLHMCQLHPQEKLSLFCETCDKLTCRDCQLSDHRDHKYKFAHEIATESRQALSTLVSEI
TIF1a_Mmus      QRPVFCPFHKKEQLKLYCETCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKL
TIF1b_Mmus      ERTVYCNVHKHEPLVLFCESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRKLLASLVKRL
TIF1g_Mmus      QRPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKL
TIF1D_Hsap      DFTLYCPLHTQEVLKLFCETCDMLTCHSCLVVEHKEHRCRHVEEVLQNQRMLLEGVTTQV
TIF1D_Mmus      DFALYCPLHTQEVLKLFCETCDVLTCHSCLMVEHKEHRCRHVEEVLQNQRMLLESVTSQV
                     * .* :* * *:**.*  ***:.* :  *::*  :.  :   ..:  :  .  .:

TIF1g_Hsap      LEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKE
TIF1b_Hsap      GDKHATLQKSTKEVRSSIRQVSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKVTEG
TIF1a_Hsap      MEKTKYIKFTGNQIQNRIIEVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKD
TIF1_Spur       QEKRKNAKVMKNNIQIIYKKMKDQESIILGRIDELFNGIRSAIDGQATALKTKIQSSTEN
bon_Dmel        NYKRFLLSSATKVIDDRQQLIHDKKKDLIKEITAMAVKITNTVNTRGKQLIMRLNEVCDS
TIF1a_Mmus      MEKTKYIKYTGNQIQNRIIEINQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKD
TIF1b_Mmus      GDKHATLQKNTKEVRSSIRQVSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKVTEG
TIF1g_Mmus      LEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKE
TIF1D_Hsap      AHKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNE
TIF1D_Mmus      AHKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNE
                  *        . :      : . .  :   :      :   :: :.  *    :   .

TIF1g_Hsap      RQMKLLQQQNDITGLSRQVKHVMNFTNWAIASGSSTALLYSKRLITFQLRHILKARCDP-
TIF1b_Hsap      QQERLERQHWTMTKIQKHQEHILRFASWALESDNNTALLLSKKLIYFQLHRALKMIVDP-
TIF1a_Hsap      HRMKLMQQQQEVAGLSKQLEHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDA-
TIF1_Spur       KCRTLKQQLIEVGTVDSALSQCYRVIHNIMTSENDVAALQQNRLVKRRVDLVLRTLLTR-
bon_Dmel        KLKVLVEKKETLQLLSDNTDHCIDFMQNALEKGSDFAILSSKKSLVRHLQKLKCQRADIP
TIF1a_Mmus      HRMKLMQQQQEVAGLSKQLEHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDA-
TIF1b_Mmus      QQERLERQHWTMTKIQKHQEHILRFASWALESDNNTALLLSKKLIYFQLHRALKMIVDP-
TIF1g_Mmus      RQMKLLQQQNDITGLSRQVKHVMNFTNWAIASGSSTALLYSKRLITFQLRHILKARCDP-
TIF1D_Hsap      RKRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKTSVPFLFSKELIVFQMQRLLETSCNT-
TIF1D_Mmus      RKRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKSSVPFLFSKELIVFQMQRLLETRCNT-
                :   * .:   :  :.   .:   .    : . .. . * .:. :  ::

TIF1g_Hsap      VPAANGAIRFHCDP-TFWAKNVVNLGNLVI-ESKPA-------P----------------
TIF1b_Hsap      VE-PHGEMKFQWDL-NAWTKSAEAFGKIVA-ERPGT-------N----------------
TIF1a_Hsap      SPVTNNTIQFHCDP-SFWAQNIINLGSLVI-EDKESQPQ---MP----------------
TIF1_Spur       QPVTELALQFKQTN-VPTRDAFKSIGSIEGMESKVL-FG---PP--------------GQ
bon_Dmel        NPEIPVRIQVQLNQVSDLQKVISQLGIIIV-DGKPYP-P---TP----------------
TIF1a_Mmus      SPVTNTTIQFHCDP-SFWAQNIINLGSLVI-EDKESQPQ---MP----------------
TIF1b_Mmus      VE-PHGEMKFQWDL-NAWTKSAEAFGKIVA-ERPGT-------N----------------
TIF1g_Mmus      VPAANGAIRFHCDP-TFWAKNVVNLGNLVI-ESKPA-------P----------------
TIF1D_Hsap      DPGSPWSIRFTWEP-NFWTKQLASLGCITT-EGGQMSRAD--APAYGGLQGSSPFYQSHQ
TIF1D_Mmus      DPGSPWSIRFTWEP-NFWTKQLASLGCITT-EGGQLTRADAAAASYGSLQGQPSFYQSHQ
                       ::.         .    :* :   :

TIF1g_Hsap      ---------------GYTPNV----------------VVGQVPPG---TNHI---SKTPG
TIF1b_Hsap      ---------------ST-------------------------------------------
TIF1a_Hsap      ---------------KQNPVV----------------EQNSQPPSGLSSNQL---SKFPT
TIF1_Spur       QQI------------RQNQGF----------------PHNMQPGLALNRAAL---VQQQA
bon_Dmel        ---------------SPNGT-----------------PQPQHPP------------RQPP
TIF1a_Mmus      ---------------KQNPVV----------------EQSSQPPGGLPSNQL---SKFPT
TIF1b_Mmus      ---------------ST-------------------------------------------
TIF1g_Mmus      ---------------GYTPNV----------------VVGQVPPG---TNHI---SKTPG
TIF1D_Hsap      SPVAQQEALSHPSHKFQSPAVCSSSVCCSHCSPVSPSLKGQVPPP---SIHPAHSFRQPP
TIF1D_Mmus      APMAQQEALSHPSHKFQSPALCSSSVCCSHCSPVSPSLKGQVPPP---SIHPAHSFRQPS


TIF1g_Hsap      QINLA-------------------------------------------------------
TIF1b_Hsap      ------------------------------------------------------------
TIF1a_Hsap      QISLA-------------------------------------------------------
TIF1_Spur       QLQAQ-------------------------------------------------------
bon_Dmel        SPNMA--------PPLRPGLPPGMPAGLSPNGPPVNFGPQNGP-----------------
TIF1a_Mmus      QISLA-------------------------------------------------------
TIF1b_Mmus      ------------------------------------------------------------
TIF1g_Mmus      QINLA-------------------------------------------------------
TIF1D_Hsap      EMVPQQLGSLQCSAL----LPREKELACSPHPPKLLQPWLETQPPVEQESTSQRLGQQLT
TIF1D_Mmus      EMVPHQLGSLQCSTL----LPREKELACSPHPPKLMQPWLEPQPPAEQESTSQRPGPQLV


TIF1g_Hsap      ---------------------------QLRLQHMQQQVYAQKHQQLQQMRMQQPP-----
TIF1b_Hsap      -----------------------------------------------------GP-----
TIF1a_Hsap      ---------------------------QLRLQHMQQQVMAQRQQ------VQRRP-----
TIF1_Spur       ---------------------------QQAQQQAQQQAQQQAHMQ--QRQLQQQQGINHA
bon_Dmel        ---------------------------PLYSNAAQQQ--------FNNL-SMSR------
TIF1a_Mmus      ---------------------------QLRLQHIQQQVMAQRQQ------VQRRP-----
TIF1b_Mmus      -----------------------------------------------------GP-----
TIF1g_Mmus      ---------------------------QLRLQHMQQQVYAQKHQQLQQMRLQQPP-----
TIF1D_Hsap      SQPVCIVPPQDVQQGAHAQPTLQTPSIQVQFGHHQKLKLSHFQQQPQ-QQLPPPP-----
TIF1D_Mmus      SQPVCIVPPQDVQPGAHAQPTIQTPSIQVQLGHHQKLKLSHFQQQPQ-QQ-PPPP-----


TIF1g_Hsap      -----------------------AP---------VPTT-TTTTQQHPRQAAPQ-------
TIF1b_Hsap      -----------------------AP---------M--A-PP-RAPGPLSKQGS-------
TIF1a_Hsap      -----------------------AP---------VGLP-NP-RMQGPIQQPSI-------
TIF1_Spur       LFSQRSIGEQLARVNRPTVCAPTIH---------IPRGLQAQQQQQQQQVRPA-------
bon_Dmel        ----------------SF------PGDGSGKVRFGG--MPPVGMQR-HGQPHV-------
TIF1a_Mmus      -----------------------AP---------VGLP-NP-RMQGPIQQPSI-------
TIF1b_Mmus      -----------------------GP---------M--A-PP-RAPGPLSKQGS-------
TIF1g_Mmus      -----------------------AP---------IPTT-TATTQQHPRQAAPQ-------
TIF1D_Hsap      -----------------------PP---------LPHP-PP-PLPPPPQQPHPPLPPSQH
TIF1D_Mmus      ----------------------------------------P-PPPPPPQHAPPPLPPSQH
                                                        .

TIF1g_Hsap      ---MLQQQPPRLISVQTMQ----------------------RGNMNCGAFQAHQMRLAQ-
TIF1b_Hsap      ---GSSQPMEVQE-----------------------------------------------
TIF1a_Hsap      ---SHQQPPPRLINFQN-------------------------------------------
TIF1_Spur       ---MQTNILPVLTNPQNTM----------------------GIRPS----TSTQLT----
bon_Dmel        ---SSSTHPQ---NMDISL----------------------RGLLNNQAAQSPNAHMAF-
TIF1a_Mmus      ---SHQHPPPRLINFQN-------------------------------------------
TIF1b_Mmus      ---GSSQPMEVQE-----------------------------------------------
TIF1g_Mmus      ---MLQQQPPRLISVQTMQ----------------------RGNMNCGAFQAHQMRLAQ-
TIF1D_Hsap      LASSQHESPPGPACSQNMDIMHHKFELEEMQKDLELLLQAQQPSLQLSQTKSPQ-HLQQT
TIF1D_Mmus      LASSQHESPPGPACSQNVDIMHHKFELEEMQKDLELLLQAQQPSLQLSQTKSPQ-HLQQT


TIF1g_Hsap      NAA-RIPGIPRHSG-PQYSMMQP-HLQRQ---HSNPGHAG----PFP-------------
TIF1b_Hsap      -------GYGFGSGDDPYSSAEP-HVSGVKRSRSGEGEVSGLMRKVP-------------
TIF1a_Hsap      -----------HSPKPNGPVLPP-HPQQL---RYPPNQNI----PRQA-IK-PNPLQ---
TIF1_Spur       ----------HGLPTSMQPVGPP-N------------VTV------TSAMT-FGDLTTAQ
bon_Dmel        NGPPSYPGGPQGAPAPAHQPMGP-QM-RP---HFMPGQQG----FSQGGGPGGGPRD---
TIF1a_Mmus      -----------HSPKPNGPVLPP-YPQQL---RYSPSQNV----PRQTTIK-PNPLQ---
TIF1b_Mmus      -------GYGFGS-DDPYSSAEP-HVSGMKRSRSGEGEVSGLLRKVP-------------
TIF1g_Mmus      NAA-RIPGIPRHSA-PQYSMMQP-HLQRQ---HSNPGHAG----PFP-------------
TIF1D_Hsap      IVG-QINYIVRQPA-PVQSQSQEETLQAT---DEPPASQG----SKP-------------
TIF1D_Mmus      IVG-QINYIVRQPA-PVQSQSQEETLQVT---EEPPAPEG----PKP-------------


TIF1g_Hsap      ----------------------------VVSVHN-TTINP--------------------
TIF1b_Hsap      ----------------------------RVSLER-LDLDL--------------------
TIF1a_Hsap      -MAFLAQQAIKQWQISSGQGTP------STTNS--TSSTP--------------------
TIF1_Spur       RKQLMAQ--VKQNQALNARSPPSVSPSAATAVRNTNSASP--------------------
bon_Dmel        -ANFMNSNARFQSQYQ------RMAN--------HAQQAA--------------------
TIF1a_Mmus      -MAFLAQQAIKQWQISSVQAPP------TTASS--SSSTP--------------------
TIF1b_Mmus      ----------------------------RVSLER-LDLDL--------------------
TIF1g_Mmus      ----------------------------VVSAHN--PINP--------------------
TIF1D_Hsap      ----------------------------ALPLDK-NTAAALPQASGEETPLSVPPVDSTI
TIF1D_Mmus      ----------------------------ALPVDK-NTAAPLPQTSGEETPHSVPPVDGTS


TIF1g_Hsap      --TSPTTA--------TMANANR-----------GPTSPSVTAIELIPSVT---NPENL-
TIF1b_Hsap      --TADSQP--------PVFK----------------------------------------
TIF1a_Hsap      --SSPTIT--------SAAGY-D-----------GKA-FGSPMIDLSSPVG---GSYNL-
TIF1_Spur       --SSMGAT--------TVRNTNS----------ASPSSMIAPANDTSGPRILSVKSERRP
bon_Dmel        --AAAAMA--------GAAGG-G-----------GGQIPSPGALQRPQMMS---NPM---
TIF1a_Mmus      --SSPTIT--------SAAGY-D-----------GKA-FSSPMIDLSAPVG---GSYNL-
TIF1b_Mmus      --TSDSQP--------PVFK----------------------------------------
TIF1g_Mmus      --TSPTTA--------TMANANR-----------GPTSPSVTAIELIPSVT---NPENL-
TIF1D_Hsap      QHSSPNVVRKHSTSLSIMGFSNTLEMELSSTRLERPLEPQIQSVSNL-TAG---APQAV-
TIF1D_Mmus      QHSSPNVVRKHATSVSIMGFSNTVEMELSSTRLARTIEPQIHRVSSL-TAA---PTHTI-
                  ::

TIF1g_Hsap      ---------------------------------------------------------PSL
TIF1b_Hsap      ------------------------------------------------------------
TIF1a_Hsap      ---------------------------------------------------------PSL
TIF1_Spur       SKSDSERSSCRFENQSSGSTMIGNGLQDTQPSSSGLEMQQGSDKTSPVQSDVQMGGTPER
bon_Dmel        ---------------------Q--------------------NV-------------SAM
TIF1a_Mmus      ---------------------------------------------------------PSL
TIF1b_Mmus      ------------------------------------------------------------
TIF1g_Mmus      ---------------------------------------------------------PSL
TIF1D_Hsap      ---------------------------------------------------------PSL
TIF1D_Mmus      ---------------------------------------------------------PSL


TIF1g_Hsap      PD-------------IPPIQLEDAGSSSLD-NLL------------------------SR
TIF1b_Hsap      ---------------------VFPGSTTEDYNLI--------------------------
TIF1a_Hsap      PD-------------I---DC--SSTIMLD-NIV------------------------RK
TIF1_Spur       PDQQMGR--------TPPLTSSATSPDALE-DILGIDLPVQVNASDIIGDIMDEVALETR
bon_Dmel        QNSLGFHGSQAGFNTGPPQTSPQLGGGGMH-SLAKWHIPQSAQQSNM-------------
TIF1a_Mmus      PD-------------I---DC--SSTIMLD-NIA------------------------RK
TIF1b_Mmus      ---------------------VFPGSTTEDYNLI--------------------------
TIF1g_Mmus      PD-------------IPPIQLEDAGSSSLD-NLL------------------------SR
TIF1D_Hsap      LS-------------APPKMV--SSLTSVQ-NQA------------------------MP
TIF1D_Mmus      LS-------------GPPQTV--SSLMSVS-NHA------------------------MP
                                        .      .

TIF1g_Hsap      Y--ISGSHLPPQPTSTM-N----------------------PSPGPSALSPGSSG---LS
TIF1b_Hsap      -------------------V---------------------IERGAAAAATGQPG---TA
TIF1a_Hsap      D--TNIDHGQPRPPSNR-TV---------------------QSPNSSVPSPGLAGPVTMT
TIF1_Spur       DSGESADNSDPAPTRES-TSE--------------------ETSGSAAEASGDGA-GSVA
bon_Dmel        ----CSQQGPLLPFANG-R-Q--------------------TSENFKI---SLKSPNTLK
TIF1a_Mmus      D--TGVDHAQPRPPSNR-TV---------------------QSPNSSVPSPGLAGPVTMT
TIF1b_Mmus      -------------------V---------------------IERGAAAAAAGQAG---TV
TIF1g_Mmus      Y--ISGSHLPPQPTSTM-N----------------------PSPGPSALSPGSSG---LS
TIF1D_Hsap      S--LTTSHLQTVPSLVHSTFQSMPNLISDSPQAMASLASDHPQAGPSLMSGHTQAVPS--
TIF1D_Mmus      S--LTASHLQPVPNLVRGTFQSTSNLRGDSSQAITGLASNHSQAGPSLMSGHTQAAPS--
                                                            .         .

TIF1g_Hsap      NS---------------------------------HTPVR--PPS---------------
TIF1b_Hsap      PA---------------------------------GTPGA--PPL---------------
TIF1a_Hsap      SV---------------------------------HPPIR--SPS---------------
TIF1_Spur       EASGSGAGSVAGASGSGAGSVAEASGDGTESVAEASGDGA--GPSGSGAGSVSEGSGSGA
bon_Dmel        NS---------------------------------TPPSL--------------------
TIF1a_Mmus      SV---------------------------------HPPIR--SPS---------------
TIF1b_Mmus      PP---------------------------------GAPGA--PPL---------------
TIF1g_Mmus      NS---------------------------------HTPVR--PPS---------------
TIF1D_Hsap      LA---------------------------------TCPLQSIPPV---------------
TIF1D_Mmus      LA---------------------------------TCPLQGMPPV---------------


TIF1g_Hsap      ----TSST--GSRGS-CGSSGRTAEKT---------------------------------
TIF1b_Hsap      ----AG------------------------------------------------------
TIF1a_Hsap      ----ASSV--GSRGS-SGSSSKPAGAD---------------------------------
TIF1_Spur       IAPGEGSS--GDPGV-VEASGSGAARA-------------------VGSE----------
bon_Dmel        -G--GGGA--GHQGHGNGSSSAQLNAA---------------------------------
TIF1a_Mmus      ----ASSV--GSRGS-SGSSSKPAGAD---------------------------------
TIF1b_Mmus      ----PG------------------------------------------------------
TIF1g_Mmus      ----TSST--GSRGS-CGSSGRTAEKS---------------------------------
TIF1D_Hsap      ----SDMQ--PETGS-SSSSGRTSGSLCPRDGADPSLENALCKVRKMESEDSTRFTDLLG
TIF1D_Mmus      ----SDVHVEPRSVS-SPGSGPAAESLGTRDGAESSLGNALC---KMESEDCTRFSDSVG
                     .

TIF1g_Hsap      ------------------------------------------------------------
TIF1b_Hsap      ------------------------------------------------------------
TIF1a_Hsap      ------------------------------------------------------------
TIF1_Spur       ------------------------------------------------------------
bon_Dmel        ------------------------------------------------------------
TIF1a_Mmus      ------------------------------------------------------------
TIF1b_Mmus      ------------------------------------------------------------
TIF1g_Mmus      ------------------------------------------------------------
TIF1D_Hsap      QGPIVPGLDAPKDLAIPSELEEPINLSVKKPPLAPVVSTSTALQQYQNPKECENFEQGAL
TIF1D_Mmus      QGPTASSLDGPKDLAIPSELEEPINLSVKKPFLAPVINTSTALQQYRNPKEYENFEQGAL


TIF1g_Hsap      ---------------SLS---F-KSDQVKV-------KQEPG----TEDEICSFSG-GVK
TIF1b_Hsap      -------------------------------------------------------MAIVK
TIF1a_Hsap      --------------STHKVPVV-MLEPIRI-------KQENS----GPPENYDFPVVIVK
TIF1_Spur       --------------DVEKHGKE-KLSRIRVFLNEMDDSMHEA----TKESIAAFWKGDVS
bon_Dmel        --------------ALGLGPAVSILSNVTS-------TNPKTPSPSTHENTKDFTEPIDK
TIF1a_Mmus      --------------STHKVPVV-MLEPIRI-------KQENS----GPPENYDFPVVIVK
TIF1b_Mmus      -------------------------------------------------------MAIVK
TIF1g_Mmus      ---------------AHS---F-KSDQVKV-------KQEPG----TEEEICSFSG-AVK
TIF1D_Hsap      ELDAKENQSIRAFNSEHKIPYV-RLERLKI-------CAASS----GE-----MPVFKL-
TIF1D_Mmus      ELDTKENSDIRAISSEPKIPYV-RLERLKI-------CAASS----GE-----MPVFKL-


TIF1g_Hsap      -QEKTEDGRRSAC-MLS--------------SP--------ESSLTPPLSTNL-------
TIF1b_Hsap      -EEETEAAIGAPPTATE--------------GP--------E---TKPVLMAL-------
TIF1a_Hsap      -QESDEESRPQN---AN--------------YP--------RSILTS-----L-------
TIF1_Spur       WEERDDQGKPRRQVIVGSLYRMTSKKYSREGWPSKLHIKMMHSGMLKPLIDLMRDHQLFF
bon_Dmel        --VRDD-------------------------------------SINDLIATI--------
TIF1a_Mmus      -QESDEESRPQN---TN--------------YP--------RSILTS-----L-------
TIF1b_Mmus      -EEETEAAIGAPPAAPE--------------GP--------E---TKPVLMPL-------
TIF1g_Mmus      -QEKTEDGRRSAC-MLS--------------SP--------ESSLTPPLSTNL-------
TIF1D_Hsap      --------KPQK---ND--------------QD--------GSFLL--------------
TIF1D_Mmus      --------KPQK---NS--------------QD--------GNFLL--------------


TIF1g_Hsap      ------------------------------------------------------------
TIF1b_Hsap      ----AEGPG--------------------AEGPR--------------------------
TIF1a_Hsap      ------------------------------------------------------------
TIF1_Spur       LKCDQECKELYRKLVAIFKNKDVFGAIRLYSKPEIILLLFYSHKHQKFFIVCPQQREQFS
bon_Dmel        ------------------------------------------------------------
TIF1a_Mmus      ------------------------------------------------------------
TIF1b_Mmus      ----TEGPG--------------------AEGPR--------------------------
TIF1g_Mmus      ------------------------------------------------------------
TIF1D_Hsap      ------------------------------------------------------------
TIF1D_Mmus      ------------------------------------------------------------


TIF1g_Hsap      ---------HLESELDALASLENHVK-----IEPADMNESCKQSGLS-------------
TIF1b_Hsap      ---------LASPSGS-TSSGLEVVA-----PEGT-------------------------
TIF1a_Hsap      ---------LLNSSQS-STSEETVLR-----SDAP--DSTGDQPGLHQD-----------
TIF1_Spur       IGFVKTMEKYFKVQRK-GASDK--PN-----PESSTVSTADGDPGTSET-----------
bon_Dmel        -------------AKL-DSNGVQVLPEGRTKTTSPQVHSSTDL-----------------
TIF1a_Mmus      ---------LLNSSQS-SASEETVLR-----SDAP--DSTGDQPGLHQE-----------
TIF1b_Mmus      ---------LASPSGS-TSSGLEVVA-----PEVT-------------------------
TIF1g_Mmus      ---------HLESELDTLTGLENHVK-----TEPTDISESCKQSGLS-------------
TIF1D_Hsap      -----II--ECGT-E-SSSMSIKVSQ--------DRLSEATQAPGLEGRKVTVTSLAGQR
TIF1D_Mmus      -----VI--ECGT-E-SSSMSIKVSQ--------NSLPDASQGPGLGGRKVTVTSLTGQQ
                                  :

TIF1g_Hsap      -SLVNGKSPI-RSLMHRSA------------------------RIGGDGNNKDDDPNEDW
TIF1b_Hsap      -----------------SA------------------------PGGGPG-T--LDDSATI
TIF1a_Hsap      -NSSNGKSEW-LDPSQKSP------------------------LHVGE-TRKEDDPNEDW
TIF1_Spur       -APTSGEKRP-IDEDVPSTSQAGTSRNGEESIEPIPTWKQGYKLRNGMQCSRSDDPNDDW
bon_Dmel        --------------SN--TQ-----------------------EV-NNKNEQKDDPNEDW
TIF1a_Mmus      -NSSNGKSEW-SDASQKSP------------------------VHVGE-TRKEDDPNEDW
TIF1b_Mmus      -----------------SA------------------------PVSGPG-I--LDDSATI
TIF1g_Mmus      -NLVNGKSPI-RNLMHRSA------------------------RIGGDGNSKDDDPNEDW
TIF1D_Hsap      PPEVEGTSPEEHRLIPR--------------------------TPGAKKGPPAPIENEDF
TIF1D_Mmus      PQEVESTSE-EHRLIPR--------------------------APGAKKNTPAPIENEDF
                                                                        .

TIF1g_Hsap      CAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPS--GDWICTFCRDIGKPEVEYDCDNLQ
TIF1b_Hsap      CRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPG--EEWSCSLCHVLPDLKEEDGSLSLD
TIF1a_Hsap      CAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPS--GEWICTFCRDLSKPEVEYDCDAPS
TIF1_Spur       CAVCNNGGNLVCCDRCPRVYHHECHVPLISEVPED-DDFDCTLCFDVVADEEEN-V----
bon_Dmel        CAVCLDGGELMCCDKCPKVFHQNCHIPAISSLPDESESWQCLLCVNIKELTKTEGS----
TIF1a_Mmus      CAVCQNGGELLCCEKCPKVFHLTCHVPTLTNFPS--GEWICTFCRDLSKPEVDYDCDVPS
TIF1b_Mmus      CRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPG--EEWSCSLCHVLPDLKEEDGSLSLD
TIF1g_Mmus      CAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPS--GDWICTFCRDIGKPEVEYDCDNMQ
TIF1D_Hsap      CAVCLNGGELLCCDRCPKVFHLSCHVPALLSFPG--GEWVCTLCRSLTQPEMEYDCENAC
TIF1D_Mmus      CAVCINGGELLCCDRCPKVYHLSCHVPALLSFPG--GEWVCTLCRSLTQPEMEYDCENAR
                * ** . *:*: *::*   :*  **:* : ..*    .: * :*  :

TIF1g_Hsap      HSKK-GKTAQ---GLSPVDQRKCERLLLYLYCH-ELSIEFQEPVPASIPNYYKIIKKPMD
TIF1b_Hsap      GADS-TGVV---AKLSPANQRKCERVLLALFCH-EPCRPLHQLATDSTF-SLDQPGGTLD
TIF1a_Hsap      HNSE-KKKTEGLVKLTPIDKRKCERLLLFLYCH-EMSLAFQDPVPLTVPDYYKIIKNPMD
TIF1_Spur       NNEN-AEKLE---GFTAREFKLCQRLLLEMYCL-EDSQPFLEPVGPEVTGYLEIIPIPMD
bon_Dmel        ---E-KSSSG---ELSALELRILQRICLELYCQYEQSLNFREPESPANTSYYEIVSSPMS
TIF1a_Mmus      HHSE-KRKSEGLTKLTPIDKRKCERLLLFLYCH-EMSLAFQDPVPLTVPDYYKIIKNPMD
TIF1b_Mmus      GADS-TGVV---AKLSPANQRKCERVLLALFCH-EPCRPLHQLATDSTF-SMEQPGGTLD
TIF1g_Mmus      HSKK-GKTAQ---GLSPVDQRKCERLLLYLYCH-ELSIEFQEPVPVSIPNYYKIIKKPMD
TIF1D_Hsap      YNQPGMRASP---GLSMYDQKKCEKLVLSLCCN-NLSLPFHEPVSPLARHYYQIIKRPMD
TIF1D_Mmus      YGHPGVRVLP---GLSMYDQKKCEKLVLSLCCN-SLSLPFHEPVSPLARHYYQIIKRPMD
                              ::  : :  ::: * : *  . .  : :          .    .:.

TIF1g_Hsap      LSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEMMKVVQVYADTQEINLKADSEV
TIF1b_Hsap      LTLIRARLQEKLSPPYSSPQEFAQDVGRMFKQFNKLTED-----------------KADV
TIF1a_Hsap      LSTIKKRLQEDY-SMYSKPEDFVADFRLIFQNCAEFNEP-----------------DSEV
TIF1_Spur       LSTIKSKLSLTSPNKYFSPRQMVEDLRVMFTNCYQYNGE-----------------TSDL
bon_Dmel        LDVIRTRLDPSSPNHYKDIAGFVSDVRLIFSNTYLFYQE-----------------DTKT
TIF1a_Mmus      LSTIKKRLQEDY-CMYTKPEDFVADFRLIFQNCAEFNEP-----------------DSEV
TIF1b_Mmus      LTLIRARLQEKLSPPYSSPQEFAQDVGRMFKQFNKLTED-----------------KADV
TIF1g_Mmus      LSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEMMKVVQVYADTQEINLKGDSEV
TIF1D_Hsap      LSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKFNYP-----------------DSEV
TIF1D_Mmus      LSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKFNYP-----------------DSEV
                *  :: :*.      *     .. *.  :* :                         :.

TIF1g_Hsap      AQAGKAVALYFEDKLTEIYSD---RTFAPLPEFEQEEDDGE-------------------
TIF1b_Hsap      -QSIIGLQRFFETRMNEAFGD---TKFSA-VLVEPPPMSLP-------------------
TIF1a_Hsap      ANAGIKLENYFEELLKNLYPE---KRFPK-PEFRNESEDNK-------------------
TIF1_Spur       GKIAQHLQRYASRFMKRYLPEYMDSNFVSSANQR--HE----------------------
bon_Dmel        YSNAKYLENFFEEQLAKWLPQ---FEGTK-PQGKRNTSNSPALLGVNATGSPSPIENGRK
TIF1a_Mmus      ANAGIKLESYFEELLKNLYPE---KRFPK-VEFRHEAEDCK-------------------
TIF1b_Mmus      -QSIIGLQRFFETRMNDAFGD---TKFSA-VLVEPPPLNLP-------------------
TIF1g_Mmus      AKAGKAVALYFEDKLSEIYSD---RTFTPLPEFEQDEDDGE-------------------
TIF1D_Hsap      AEAGRCLEVFFEGWLKEIYPE---KRFAQ-PRQED-SDSEE-------------------
TIF1D_Mmus      AEAGRCLEVFFEGWLKEIYPD---KCFAQ-PQQED-SDSED-------------------
                 .    :  : .  :     :            .

TIF1g_Hsap      ---VT--EDSD-------------EDFIQPRRKRLKSDER-P----------VHIK
TIF1b_Hsap      ---GA--GLSS-------------QEL----------SGG-P----------GDGP
TIF1a_Hsap      ---FS--DDSD-------------DDFVQPRKKRLKSIEE-R----------QLLK
TIF1_Spur       ---------------------------DRPNKRRKQEHPT-P---------VFHIR
bon_Dmel        SCGSASLGDSD-------------GACLPAKRARRSA-----------------HE
TIF1a_Mmus      ---FS--DDSD-------------DDFVQPRKKRLKSTED-R----------QLLK
TIF1b_Mmus      ---SA--GLSS-------------QEL----------S-G-P----------GDGP
TIF1g_Mmus      ---VT--EDSD-------------EDFIQPRRKRLKSDER-P----------VHIK
TIF1D_Hsap      ---VS--SESGCSTPQGFPWPPYMQEGIQPKRRRRHMENERAKRMSFRLANSISQV
TIF1D_Mmus      ---VS--GESGCSTPQGFPWPPYMQEGIQPKRRRRHMENEKTKRVSFRLANSISQV