TXK_Hsap ------------------------------------------------------------
TEC_Hsap ------------------------------------------------------------
ITK_Hsap ------------------------------------------------------------
ITK_Mmus ------------------------------------------------------------
BTK_Mmus ------------------------------------------------------------
BMX_Mmus ------------------------------------------------------------
BMX_Hsap ------------------------------------------------------------
BTK_Hsap ------------------------------------------------------------
Btk29A_Dmel ------------------------------------------------------------
TEC_Mmus ------------------------------------------------------------
TXK_Mmus ------------------------------------------------------------
TEC_Spur ------------------------------------------------------------
AqueK442_Aque ------------------------------------------------------------
AqueK442~b_Aque KGQAMHYLIRIDEEKKYYIYNMHRFPTVTELIEYHKLNGGGLPTRLRQPPALLVPNQPAL
AqueK443_Aque ------------------------------------------------------------
AqueK444_Aque ------------------------------------------------------------
AqueK445_Aque ------------------------------------------------------------
AqueK446_Aque ------------------------------------------------------------
AqueK447_Aque ------------------------------------------------------------
AqueK448_Aque ------------------------------------------------------------
TXK_Hsap ----------------LAFIKEIGSGQFGVVHLGEWR-SHIQVAIKAINEGSMSEEDFIE
TEC_Hsap ----------------LTFMRELGSGLFGVVRLGKWR-AQYKVAIKAIREGAMCEEDFIE
ITK_Hsap ----------------LTFVQEIGSGQFGLVHLGYWL-NKDKVAIKTIREGAMSEEDFIE
ITK_Mmus ----------------LTFVQEIGSGQFGLVHLGYWL-NKDKVAIKTIQEGAMSEEDFIE
BTK_Mmus ----------------LTFLKELGTGQFGVVKYGKWR-GQYDVAIKMIREGSMSEDEFIE
BMX_Mmus ----------------ITLLKELGNGQFGVVQLGQWK-GQYDVAVKMIKEGAMSEDEFFQ
BMX_Hsap ----------------ITLLKELGSGQFGVVQLGKWK-GQYDVAVKMIKEGSMSEDEFFQ
BTK_Hsap ----------------LTFLKELGTGQFGVVKYGKWR-GQYDVAIKMIKEGSMSEDEFIE
Btk29A_Dmel ----------------LMLMEELGSGQFGVVRRGKWR-GSIDTAVKMMKEGTMSEDDFIE
TEC_Mmus ----------------LTFMRELGSGLFGVVRLGKWR-AQYKVAIKAIREGAMCEEDFIE
TXK_Mmus ----------------LAFVKEIGSGQFGVVHLGEWR-AHIPVAIKAINEGSMSEEDFIE
TEC_Spur ----------------LKILQELGRGQFGIVHLAKLTHNNRFVAVKRMQEGSMSEEDFID
AqueK442_Aque ----------------------------KRVVAGQWR-NEVDVAIKI-MEGALNEDDLIK
AqueK442~b_Aque RVSSAFDDKWRIDKSELSLGKELGSGQFKRVVAGQWR-NEVDVAIKI-MEGALNEDDLIK
AqueK443_Aque ----------------LSLGDELSSGEFKRVVIGQWC-NKVDVAIKMIKEDAMNEDDFIE
AqueK444_Aque ----------------LSFGKELGSGEFKRVVAGQWR-NKVDVAIKMIKEDVMNEDDFIE
AqueK445_Aque ----------------LSLGKELGSGEFKKVVAGQWR-NEVDVAIKI-MEGALNEDDLIK
AqueK446_Aque -------------------------------------------------------DDFIE
AqueK447_Aque ----------------LSFGKELGSGEFKRVVAGQWR-NKGDIAIKMIKEDTMNEEHLIE
AqueK448_Aque ----------------LSLGKELGSGQFGRVVAGQWR-NKVDVAIKMMKEGAMNEDDFIE
:.::.
TXK_Hsap EAKVMMKLSHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRENKGK-LR-KEMLLSVC
TEC_Hsap EAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGH-FS-RDVLLSMC
ITK_Hsap EAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGL-FA-AETLLGMC
ITK_Mmus EAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRSQRGL-FA-AETLLGMC
BTK_Mmus EAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHR-FQ-TQQLLEMC
BMX_Mmus EAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLKSHGKG-LE-SCQLLEMC
BMX_Hsap EAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGKG-LE-PSQLLEMC
BTK_Hsap EAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHR-FQ-TQQLLEMC
Btk29A_Dmel EAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMC
TEC_Mmus EAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGH-FS-RDMLLSMC
TXK_Mmus EAKVMMKLSHSRLVQLYGVCIQQKPLYIVTEFMENGCLLDYLRERKGQ-LQ-KALLLSMC
TEC_Spur EAKVMKELQHENLVQLYGVTSAQRPMCIVTEYMSKGCLLSYLRTHKFMLLENTAILIYMT
AqueK442_Aque EAILMQKFQHDNLVKLCGVCIRQRSVYIITELMVNGSLLQYLCNNQRL-VNKTDILLDMA
AqueK442~b_Aque EAILMQKFQHDNLVKLCGVCIRQRSVYIITELMVNGSLLQYLCNNQRL-VNKTDILLDMA
AqueK443_Aque EAILMMKFQHDNLVKLYGVCIRQGPVYIITELMVNGSLLQYLRKNKHL-VDKTDIILDMA
AqueK444_Aque EAILMLKFQHDNLVKLYGVCIRQGPVYIITELMANGCLLQYIRNNQHL-VKKTGIILDMA
AqueK445_Aque EATLMEKFQHDNLVKLYGVCIGQGPVYIITELNGNGSLLQYLCNNQHL-VNKTDILLDMA
AqueK446_Aque EAILMIKFQHDNLVKLYGVCIRQGPVYIITELMANGSLLQYLRNNQHL-VDNTDIILDMA
AqueK447_Aque EAILMLKFQHDNLVKLYGVCIGQGPVYIITELMANGCLLQYLRNNQHL-VKKTDIMLDMA
AqueK448_Aque EAKVMQKFQHDNLVKLYGVCIKQGAVYIITELMVNGCLLQYLRNNKHL-VEKTDIILDMA
** * :: * .**:: ** . .: :: * .*.* .:: . :: :
TXK_Hsap QDICEGMEYLERNGYIHRDL-----------------------------AARNCLVSSTC
TEC_Hsap QDVCEGMEYLERNSFIHRDL-----------------------------AARNCLVSEAG
ITK_Hsap LDVCEGMAYLEEACVIHRDL-----------------------------AARNCLVGENQ
ITK_Mmus LDVCEGMAYLEKACVIHRDL-----------------------------AARNCLVGENQ
BTK_Mmus KDVCEAMEYLESKQFLHRDL-----------------------------AARNCLVNDQG
BMX_Mmus YDVCEGMAFLESHQFIHRDL-----------------------------AARNCLVDSDL
BMX_Hsap YDVCEGMAFLESHQFIHRDL-----------------------------AARNCLVDRDL
BTK_Hsap KDVCEAMEYLESKQFLHRDL-----------------------------AARNCLVNDQG
Btk29A_Dmel IQVSKGMTYLERHNYIHRDL-----------------------------AARNCLVGSEN
TEC_Mmus QDVCEGMEYLERNSFIHRDL-----------------------------AARNCLVNEAG
TXK_Mmus QDICEGMAYLERSCYIHRDL-----------------------------AARNCLVSSAC
TEC_Spur QQVCFGMAYLESKGFIHRDL-----------------------------AARNCLVGDKH
AqueK442_Aque IQICATMKFLEQSGFIHRNL-----------------------------PARNCQVGYSN
AqueK442~b_Aque IQICATMKFLEQSGFIHRNL-----------------------------PARNCQVGYSN
AqueK443_Aque LQICAAMKFFEQSGFIHRNL-----------------------------AAINCLVGDRN
AqueK444_Aque IQISDGMKFFEQSGLIHRDLYMEQISNLKHKIKVTTKVAKKFQLVMINMAARNCLVGDRN
AqueK445_Aque IQICAAMKFLEQSGFIHRNL-----------------------------AARNCLVGDRN
AqueK446_Aque IQICAAMKFFEQSGFIHRNL-----------------------------AARNCLVGDRN
AqueK447_Aque IQICDAMKFFEQSGFIHRDL-----------------------------AARNCLVGYSN
AqueK448_Aque IQICAAMKFLEQSGFIHRDL-----------------------------AARNCLVGDRN
::. * ::* :**:* .* ** *.
TXK_Hsap IVKISDFGMTRYVLDDEYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTE
TEC_Hsap VVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEVFTE
ITK_Hsap VIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSE
ITK_Mmus VIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSE
BTK_Mmus VVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSL
BMX_Mmus SVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSL
BMX_Hsap CVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSL
BTK_Hsap VVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSL
Btk29A_Dmel VVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTC
TEC_Mmus VVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEIFTE
TXK_Mmus VVKISDFGMARYVLDDEYISSSGAKFPVKWCPPEVFHFNKYSSKSDVWSFGVLMWEVFTE
TEC_Spur IVKVADFGLTRYVMDDEYTSS-GTKFPIKWAPPEVLHYTRFSSKSDVWAFGILMWEVFSG
AqueK442_Aque IVKVGGFSSARFVPDDEYEASVGVKYAVRWSPPEVITHARYSSK-DVWSYGKLLWELWSG
AqueK442~b_Aque IVKVGGFSSARFVPDDEYEASVGVKYAVRWSPPEVITHARYSSK-DVWSYDILLWELWSG
AqueK443_Aque IVKVGGFSSARFVPDDEYTASEGAEFPARWSAPEVITHARYSSKSDIWSYGILLWELWTG
AqueK444_Aque IVKVGGFSLARFVPDDEYTASVGAKYAVKWSPPEVITHARFSSKSDIWSYGILLWELWSG
AqueK445_Aque IVKVGSFSSARFVPDDEYKASVGAKYAVRWSAPEVITHARFSSKSDIWSY----------
AqueK446_Aque IVKVAGFGSARYVPDNEYTASEGTEFAVKWIAPEVITHARYSSKSDVWSYGILLWELWTG
AqueK447_Aque IVKVGGFSLARFVPDDQYTASEGAKYAVKWSPPEVITHGRFSSKSDVWSYGILLWELWSS
AqueK448_Aque IVKVGDFGLARFVTDDEYTASEGTKFPIKWAAPEVITHARFSSKSDVWSYGILLWELWSG
:*:..*. :*:* *::* :* * ::. :* .***: . ::*** *:*::
TXK_Hsap GKMPFENKSNLQVVEAISE-GFRLYRPHLAPMSIYEVMYSCWH---EKPEGRPTFAELLR
TEC_Hsap GRMPFEKYTNYEVVTMVTR-GHRLYQPKLASNYVYEVMLRCWQ---EKPEGRPSFEDLLR
ITK_Hsap GKIPYENRSNSEVVEDIST-GFRLYKPRLASTHVYQIMNHCWK---ERPEDRPAFSRLLR
ITK_Mmus GKIPYENRSNSEVVEDIST-GFRLYKPRLASCHVYQIMNHCWK---EKPEDRPPFSQLLS
BTK_Mmus GKMPYERFTNSETAEHIAQ-GLRLYRPHLASERVYTIMYSCWH---EKADERPSFKILLS
BMX_Mmus GKQPYDLYDNSEVVVKVSQ-GHRLYRPQLASDTIYQIMYSCWH---ELPEKRPTFQQLLS
BMX_Hsap GKQPYDLYDNSQVVLKVSQ-GHRLYRPHLASDTIYQIMYSCWH---ELPEKRPTFQQLLS
BTK_Hsap GKMPYERFTNSETAEHIAQ-GLRLYRPHLASEKVYTIMYSCWH---EKADERPTFKILLS
Btk29A_Dmel GKMPYGRLKNTEVVERVQR-GIILEKPKSCAKEIYDVMKLCWS---HGPEERPAFRVLMD
TEC_Mmus GRMPFEKNTNYEVVTMVTR-GHRLHRPKLASKYLYEVMLRCWQ---ERPEGRPSFEDLLR
TXK_Mmus GKMPFENKSNLQVVEAISQ-GFRLYRPHLAPMTIYRVMYSCWH---ESPKGRPTFAELLQ
TEC_Spur GLAPYPAMSNVEVVDQVTRHNYRMERPDHCPYQMYRIMKDC-------------------
AqueK442_Aque SNNPYPAFSNIQVLDQVER-GYRLEKPKLCPYKVYALMRRSWRIGKRYPKDRPLFSGLSD
AqueK442~b_Aque SNNPYPAFSNIQVLDQ--------------------------------------------
AqueK443_Aque GKIPYPAFTTPEILDGVLK-GYRLEKPKLCPSNIYDLMTRSWE---KNPFKRPSFAVLLD
AqueK444_Aque GKTPYPAFTNPQALDEVSK-GYRLEKPKLCPSKVYDLMKRSWQ---K-------------
AqueK445_Aque ------------------------------------------------------------
AqueK446_Aque GKTPYPAFTNPQVLDEVLR-GYRLEKPKLCPSKIYDLMKRSWQ-----------------
AqueK447_Aque GKNPYLGISNPLVLDKVLS-GYRLEKPKLCPSKVYDLMKRSWQ---VNPSDRPSFAVLLD
AqueK448_Aque GKTPYPAFTNPQVLDEVLR-GYRLENPKLCPPEVYDLMKKSWQ---ANPEDRPSFAVLSD
TXK_Hsap AVTE
TEC_Hsap T--I
ITK_Hsap Q--L
ITK_Mmus Q--L
BTK_Mmus NILD
BMX_Mmus AIEP
BMX_Hsap SIEP
BTK_Hsap NILD
Btk29A_Dmel Q-LA
TEC_Mmus T--I
TXK_Mmus VLTE
TEC_Spur ---W
AqueK442_Aque S--L
AqueK442~b_Aque ---V
AqueK443_Aque Y--L
AqueK444_Aque ---G
AqueK445_Aque ----
AqueK446_Aque ----
AqueK447_Aque S--L
AqueK448_Aque S-LK