Protein (view, download) , Domain (view, download)
mig-15_Cele     MSSS-----------GLDEIDLNSLRDPAGIFELIEVVGNGTYGQVYKGRHVKTAQLAAI
msn_Dmel        MAHQQQQQLAPSVNCSLDDIDLTALKDPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAAI
HGK_Mmus        MAND-------SPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAI
TNIK_Mmus       MASD-------SPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAI
MINK_Mmus       MGDP-------APARSLDDIDLSALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAI
NRK_Mmus        MAGP-------GGWRDREVTDLGHLPDPTGIFSLDKTIGLGTYGRIYLGLHEKTGAFTAV
MSN_Spur        -------------------IDLKGLRDPSGVFHVLKKMGNGFRGSVMRSYHRKKGILKRI
NRK_Hsap        MAGP-------GGWRDREVTDLGHLPDPTGIFSLDKTIGLGTYGRIYLGLHEKTGAFTAV
MINK_Hsap       MGDP-------APARSLDDIDLSALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAI
TNIK_Hsap       MASD-------SPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAI
HGK_Hsap        MAND-------SPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAI
AqueK232_Aque   MSP----------FKRR-----VQTKDPEGIFELIEVVGNGTYGQVFKGRHVKTGQLAAI
                                          ** *:* : : :* *  * :  . * *.. :  :

mig-15_Cele     KIMNIN------------------------EDEEDEIKLEINMLKKHSHHRNVATYYGAF
msn_Dmel        KVMDVT------------------------EDEEEEIKLEINVLKKYSNHRNIATYYGAF
HGK_Mmus        KVMDVT------------------------EDEEEEIKLEINMLKKYSHHRNIATYYGAF
TNIK_Mmus       KVMDVT------------------------GDEEEEIKQEINMLKKYSHHRNIATYYGAF
MINK_Mmus       KVMDVT------------------------EDEEEEIKQEINMLKKYSHHRNIATYYGAF
NRK_Mmus        KVMNARKTPLPEIGRRVRVNKYQKSVGWRYSDEEEDLRTELNLLRKYSFHKNIVSFYGAF
MSN_Spur        ALTMVT------------------------GNFREQLKSFSFLFVQYSHHRNIATYYGAF
NRK_Hsap        KVMNARKTPLPEIGRRVRVNKYQKSVGWRYSDEEEDLRTELNLLRKYSFHKNIVSFYGAF
MINK_Hsap       KVMDVT------------------------EDEEEEIKQEINMLKKYSHHRNIATYYGAF
TNIK_Hsap       KVMDVT------------------------GDEEEEIKQEINMLKKYSHHRNIATYYGAF
HGK_Hsap        KVMDVT------------------------EDEEEEIKLEINMLKKYSHHRNIATYYGAF
AqueK232_Aque   KIMEVT------------------------EDEEEEIRLEVDVLRKYSYHTNIATYYGAF
                 :                             : .::::    :: ::* * *:.::****

mig-15_Cele     IKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTKGGSLKEEWIAYICREILRGLYHLHQS
msn_Dmel        IKKSP--PGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILRGLSYLHSN
HGK_Mmus        IKKSP--PGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIH
TNIK_Mmus       IKKNP--PGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQH
MINK_Mmus       IKKSP--PGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAH
NRK_Mmus        FKLSP--PGQRHQLWMVMELCAAGSVTDVVRMTSNQSLKEDWIAYICREILQGLAHLHAH
MSN_Spur        IKKGV--KNHDDQLWLVMEFCGAGSVTDLVKATKGNALKEEWIAYICREILR--------
NRK_Hsap        FKLSP--PGQRHQLWMVMELCAAGSVTDVVRMTSNQSLKEDWIAYICREILQGLAHLHAH
MINK_Hsap       IKKSP--PGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAH
TNIK_Hsap       IKKNP--PGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQH
HGK_Hsap        IKKSP--PGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIH
AqueK232_Aque   VKKSE--PGTEDQLWLVMEFCGAGSITDLVKSTKTRSLKEEWIAYVAREVLRGLSHLHKN
                .*      .  .***:*** *.:**:**::: *.  :***: ***:.**:*:

mig-15_Cele     KVIHRDIKGQNVLLTDSAEVKLVDFGVSAQLDKTVGRRNTFIGTPYWMAPEVIACDESPE
msn_Dmel        KVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPD
HGK_Mmus        HVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPD
TNIK_Mmus       KVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPD
MINK_Mmus       KVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPD
NRK_Mmus        RVIHRDIKGQNVLLTHNAEVKLVDFGVSAQVSRTNGRRNSFIGTPYWMAPEVIDCDEDPR
MSN_Spur        --------------------KIVDFGVSAQLDKTIGRRNTFIGTPYWMAPEVIACDENPD
NRK_Hsap        RVIHRDIKGQNVLLTHNAEVKLVDFGVSAQVSRTNGRRNSFIGTPYWMAPEVIDCDEDPR
MINK_Hsap       KVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPD
TNIK_Hsap       KVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPD
HGK_Hsap        HVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPD
AqueK232_Aque   KVIHRDIKGQNVLLTDNADIKLVDFGVSAQLDRTIGKRNTFIGTPYWMAPEVIACDQDPH
                                    *:********:.:* *:**:************* **:.*

mig-15_Cele     ATYDSRSDLWSLGITALEMAEGHPPLCDMHPMRALFLIPRNPPPKLKRNKKWTKKFETFI
msn_Dmel        ATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRLK-SKKWSKKFHGFI
HGK_Mmus        ATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLK-SKKWSKKFFSFI
TNIK_Mmus       ATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLK-SKKWSKKFQSFI
MINK_Mmus       ATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLK-SKKWSKKFIDFI
NRK_Mmus        RSYDYRSDVWSVGITAIEMAEGAPPLCNLQPLEALFVILRESAPTVK-SSGWSRKFHNFM
MSN_Spur        ATYDNKSDLWSLGITALEMAEGQPPLCDMHPMRALFLIPRNPKPKLK-SKKWNKKFMDFV
NRK_Hsap        RSYDYRSDVWSVGITAIEMAEGAPPLCNLQPLEALFVILRESAPTVK-SSGWSRKFHNFM
MINK_Hsap       ATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLK-SKKWSKKFIDFI
TNIK_Hsap       ATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLK-SKKWSKKFQSFI
HGK_Hsap        ATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLK-SKKWSKKFFSFI
AqueK232_Aque   ATYDYRSDQWSLGITSIEIAEGEPPLCSMHPMRALFLIPRNPPPRLKMPKKWSPKFTSFI
                 :** :** ** ***::*:**. ****.::*:.***:* *:. * :*  . *. **  *:

mig-15_Cele     ETVLVKDYHQRPYTGALLRHPFIKEQPHEQTIRHSIKEHIDRNRR--VKKDDA-DYEYSG
msn_Dmel        DTVLVKDYHQRPYTENLLKHGFIKDQPTDRQVRIQLKDHIDRCKKRKQEKERE-DYRYSG
HGK_Mmus        EGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDET-EYEYSG
TNIK_Mmus       ESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDET-EYEYSG
MINK_Mmus       DTCLIKTYLSRPPTEQLLKFPFIRDQPTERQVRIQLKDHIDRSRKKRGEKEET-EYEYSG
NRK_Mmus        EKCTIKNFLFRPTSANMLQHPFVRDIKNERHVVESLTRHLTGIIKKRQKKGIPLIFEREE
MSN_Spur        DKCLIKNYQQRPDTNQLLKHSFIKDLPNERQVRIQLKDHIDRTPRE---DLST-DYEYNS
NRK_Hsap        EKCTIKNFLFRPTSANMLQHPFVRDIKNERHVVESLTRHLTGIIKKRQKKGIPLIFEREE
MINK_Hsap       DTCLIKTYLSRPPTEQLLKFPFIRDQPTERQVRIQLKDHIDRSRKKRGEKEET-EYEYSG
TNIK_Hsap       ESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDET-EYEYSG
HGK_Hsap        EGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDET-EYEYSG
AqueK232_Aque   DQCLTKDPTKRPTSDELLRHPFVNDFP-ERQVRIQMKDQIDRMKRKKVMDDHL-SSDEEG
                :    *    ** :  :::. *:.:   :: :  .:. ::    :    .        .

mig-15_Cele     SEDDEPS-PNNRGPSMG--IR-------------DDS--ESSSMIPMDNT----------
msn_Dmel        SDNDDDE-PQLAGEH------------------------SSIVQAPGGDT----------
HGK_Mmus        SEEEEEEVPEQEGEP------------------------SSIVNVPGEST----------
TNIK_Mmus       SEEEEEE--NDSGEP------------------------SSILNLPGEST----------
MINK_Mmus       SEEEDDS-HGEEGEP------------------------SSIMNVPGEST----------
NRK_Mmus        AIKEQYTVRRFRGPSCTHELLRLPTSSRCRPLRVLHGEPSQPRWLPDREEPQVQALQQLQ
MSN_Spur        NESDEEPEIEDEGEP------------------------SSILPGPSEST----------
NRK_Hsap        AIKEQYTVRRFRGPSCTHELLRLPTSSRCRPLRVLHGEPSQPRWLPDREEPQVQALQQLQ
MINK_Hsap       SEEEDDS-HGEEGEP------------------------SSIMNVPGEST----------
TNIK_Hsap       SEEEEEE--NDSGEP------------------------SSILNLPGEST----------
HGK_Hsap        SEEEEEEVPEQEGEP------------------------SSIVNVPGEST----------
AqueK232_Aque   SLEQPT-I-KKGGG----------------------------------------------
                  .:        *

mig-15_Cele     -LRKGFQKLQESSRGFAEPGAQQ-LRRLPQQPA---------------------------
msn_Dmel        -LRRNFQQIQEG-RLAAEQQQQHHLMAQAQAQAA---AAHAAAQAQAQLQQQQQQAA---
HGK_Mmus        -LRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLE
TNIK_Mmus       -LRRDFLRLQLANKERSEALRRQQL--EQQQRENEEHKRQLLAERQKRIEEQKEQRRRLE
MINK_Mmus       -LRREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVE
NRK_Mmus        GAARVFMPLQALDS-APKPLKGQAQAPQRLQGA--AR-VFMPLQAQVKAKASKPLQMQIK
MSN_Spur        -LRRNFLRLQQQQQQQEEGG-----------------------------------RRRLE
NRK_Hsap        GAARVFMPLQALDS-APKPLKGQAQAPQRLQGA--AR-VFMPLQAQVKAKASKPLQMQIK
MINK_Hsap       -LRREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVE
TNIK_Hsap       -LRRDFLRLQLANKERSEALRRQQL--EQQQRENEEHKRQLLAERQKRIEEQKEQRRRLE
HGK_Hsap        -LRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLE
AqueK232_Aque   ------------------------------------------------------------


mig-15_Cele     -----PAPFQYQQSRYVEPRRESSE----------------VKLRAVSSRGAAD------
msn_Dmel        ------------------------------------------------------------
HGK_Mmus        EQQRREREARRQQERE--QRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYI
TNIK_Mmus       EQQRREKELRKQQERE--QRRHYEEQM-----------------RREEERRRAEHEQEYI
MINK_Mmus       EQQRREREQRKLQEKE--QQRRLEDM---------------QALRREEERRQAEREQEYK
NRK_Mmus        APPRLRRAARVLMPLQ--AQVRAPRL---------------LQVQSQVSKKQQAQTQTSE
MSN_Spur        DD----------------------------------------------------------
NRK_Hsap        APPRLRRAARVLMPLQ--AQVRAPRL---------------LQVQSQVSKKQQAQTQTSE
MINK_Hsap       EQQRREREQRKLQEKE--QQRRLEDM---------------QALRREEERRQAEREQEYK
TNIK_Hsap       EQQRREKELRKQQERE--QRRHYEEQM-----------------RREEERRRAEHEQEYI
HGK_Hsap        EQQRREREARRQQERE--QRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYI
AqueK232_Aque   ------------------------------------------------------------


mig-15_Cele     -----------------------------------------GPRHSPAS-----------
msn_Dmel        ------------AAAAAAAHAAQQAQQAA----------------------------QQA
HGK_Mmus        RRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDH
TNIK_Mmus       RRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQR
MINK_Mmus       -----------------------------RKQLEEQRQSERLQRQLQQEHAYLKSLQQQQ
NRK_Mmus        -----------------------------PQDLDQVPEEFQGQDQVPEQQRQGQAPEQQQ
MSN_Spur        ------------------------------------------------------------
NRK_Hsap        -----------------------------PQDLDQVPEEFQGQDQVPEQQRQGQAPEQQQ
MINK_Hsap       -----------------------------RKQLEEQRQSERLQRQLQQEHAYLKSLQQQQ
TNIK_Hsap       RRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQR
HGK_Hsap        RRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDH
AqueK232_Aque   ------------------------------------------------------------


mig-15_Cele     -RPRPVSHHQRSP--Q-QSHPAAPHLADLANYEKRRRS-EREERRERERQA-HHAMPIAR
msn_Dmel        QAQQPQ---------AN-RQP------------KPPSRQQVEE-----------------
HGK_Mmus        RRPHPQHSQQPPPPQQERSKPSFHAPEPKAHYEPADRAREVEDRFRKTNH-SSPEAQ-SK
TNIK_Mmus       QEQRPV-----------EKKPLYHYKEGMSPSEKPAWAKEVEERSRLNRQ-SSPAMP-HK
MINK_Mmus       QQQQLQKQQQQQLLPG-DRKPLYHYGRGMNPADKPAWAREVEERTRMNKQQNSPLAK-SK
NRK_Mmus        RHNQVPEQELEQNQAPE--QPEVQ-EQAAEPAQAETEAEE-PESLRVNAQVFLPLLS-QD
MSN_Spur        ------------PPST------------------------------------NPLMR-SA
NRK_Hsap        RHNQVPEQELEQNQAPE--QPEVQ-EQAAEPAQAETEAEE-PESLRVNAQVFLPLLS-QD
MINK_Hsap       QQQQLQKQQQQQLLPG-DRKPLYHYGRGMNPADKPAWAREVEERTRMNKQQNSPLAK-SK
TNIK_Hsap       QEQRPV-----------EKKPLYHYKEGMSPSEKPAWAKEVEERSRLNRQ-SSPAMP-HK
HGK_Hsap        RRPHPQHSQQPPPPQQERSKPSFHAPEPKAHYEPADRAREVEDRFRKTNH-SSPEAQ-SK
AqueK232_Aque   ------------------------------------------------------------


mig-15_Cele     VSASVPAP---QQSRKM--S---EPLLITHVKPEDLDVL-----ASELSKMGGHHNGRSR
msn_Dmel        -------------------PG-PPAR-PPQRLIVVPDP-PHANRP--LPPT-P-KCGEPA
HGK_Mmus        QTGRVLEPPVPSRSESFSN-GNSESVHPALQRPAEPQVQ-----WSHLASLKNNVSPVSR
TNIK_Mmus       VANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQI-------PHLVAVKSQGPALTA
MINK_Mmus       PGSTGPEPPIPQASPGP--PG-PLSQTPPMQRPVEPQEGPHKSLVAHRVPLKPYAAPVPR
NRK_Mmus        H---------------------------HVLLPLHLDT-------QVLIPVEGQTEGSPQ
MSN_Spur        PSRAGPV-----------------------------------------------------
NRK_Hsap        H---------------------------HVLLPLHLDT-------QVLIPVEGQTEGSPQ
MINK_Hsap       PGSTGPEPPIPQASPGP--PG-PLSQTPPMQRPVEPQEGPHKSLVAHRVPLKPYAAPVPR
TNIK_Hsap       VANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQI-------PHLVAVKSQGPALTA
HGK_Hsap        QTGRVLEPPVPSRSESFSN-GNSESVHPALQRPAEPQVQ-----WSHLASLKNNVSPVSR
AqueK232_Aque   ------------------------------------------------------------


mig-15_Cele     EESMS-----------------------------------------------P-P-----
msn_Dmel        GQTPQQQQRNSQNNFKPSLPPRRPEDHLDVLAAQLSELGVVFSQQPQPQTAAGGQGSQQ-
HGK_Mmus        SHSFSDPSPKFAHHHLRS---QDP---------CPPSRSEVLSQSSDSKSEAP--DPT--
TNIK_Mmus       SQSVHEQPTKGLSGFQEA---L-N---------VTSHRVEMPRQNSDPTSENP-PLPTRI
MINK_Mmus       SQSLQDQPTRNLAAFPAS---HDPDPAIPAPTATPSARGAVIRQNSDPTSEGPGPSPN--
NRK_Mmus        AQAWTLEPPQAIGSVQAL---I-E---------GLS-RDLLRAPNSNNSKPLG-PLQTLM
MSN_Spur        ---------------------------------------------------------N--
NRK_Hsap        AQAWTLEPPQAIGSVQAL---I-E---------GLS-RDLLRAPNSNNSKPLG-PLQTLM
MINK_Hsap       SQSLQDQPTRNLAAFPAS---HDPDPAIPAPTATPSARGAVIRQNSDPTSEGPGPSPN--
TNIK_Hsap       SQSVHEQPTKGLSGFQEA---L-N---------VTSHRVEMPRQNSDPTSENP-PLPTRI
HGK_Hsap        SHSFSDPSPKFAHHHLRS---QDP---------CPPSRSEVLSQSSDSKSEAP--DPT--
AqueK232_Aque   ------------------------------------------------------------


mig-15_Cele     ----------------PPAPPPREASISSITDT-IDVGELDNGADAEWDDLKDIMMNG-E
msn_Dmel        ---------QAQ-PEAPPRNNRQSSGLSSSGGSASGGG-------------------GSS
HGK_Mmus        ----QKAWSRSDSDEVPPRVPVRTTSRSPVLSR-RDSP-------------------L-Q
TNIK_Mmus       EKFDRSSWLRQE-EDIPPKVPQRTTSISPALAR-KNSP-------------------G-N
MINK_Mmus       ----PPAWVRPD-NEAPPKVPQRTSSIATALNT-SGAG-------------------G-S
NRK_Mmus        ENLSSNRFYSQP-EQAREKK-SKVSTLRQALAK-RLSP-------------------K-R
MSN_Spur        ----PPCHPHPP-AESRPKLRQGSAKLSVCRNV-TVTS-------------------S-S
NRK_Hsap        ENLSSNRFYSQP-EQAREKK-SKVSTLRQALAK-RLSP-------------------K-R
MINK_Hsap       ----PPAWVRPD-NEAPPKVPQRTSSIATALNT-SGAG-------------------G-S
TNIK_Hsap       EKFDRSSWLRQE-EDIPPKVPQRTTSISPALAR-KNSP-------------------G-N
HGK_Hsap        ----QKAWSRSDSDEVPPRVPVRTTSRSPVLSR-RDSP-------------------L-Q
AqueK232_Aque   -------------------------------DT-TGSG-------------------G--


mig-15_Cele     GTLRGPNKPLPP------------------------------------------------
msn_Dmel        KPAAALP--QQS------------------------------------------------
HGK_Mmus        GSGQQNSQAGQR------------------------------------------------
TNIK_Mmus       GSALGPRLGSQP------------------------------------------------
MINK_Mmus       RPAQAVRA--RP------------------------------------------------
NRK_Mmus        FRAKSS-WRPEKLELSDLEARRQRRQRRWEDIFNQHEEELRQVDKDKEDESSDNDEVFHS
MSN_Spur        LRAMSWRS--WN------------------------------------------------
NRK_Hsap        FRAKSS-WRPEKLELSDLEARRQRRQRRWEDIFNQHEEELRQVDKDKEDESSDNDEVFHS
MINK_Hsap       RPAQAVRA--RP------------------------------------------------
TNIK_Hsap       GSALGPRLGSQP------------------------------------------------
HGK_Hsap        GSGQQNSQAGQR------------------------------------------------
AqueK232_Aque   ------------------------------------------------------------


mig-15_Cele     ---------------------------------------------TPTDGENTLVSDVRR
msn_Dmel        ---------------------------------------NNH------------------
HGK_Mmus        ---------------------------------------NSTSSIEPRLLWERVEKLVPR
TNIK_Mmus       ---------------------------------------IRASNPDLRRTEPILESPLQR
MINK_Mmus       ---------------------------------------RS-NSAWQIYLQRRAERGTPK
NRK_Mmus        IQAEVQIEPLKPYISNPKKIEVQERSPSVPNNQDHAHHVKFSSSVPQRSLLEQAQKPIDI
MSN_Spur        ---------------------------------------AD-ITLCPIFYE---------
NRK_Hsap        IQAEVQIEPLKPYISNPKKIEVQERSPSVPNNQDHAHHVKFSSSVPQRSLLEQAQKPIDI
MINK_Hsap       ---------------------------------------RS-NSAWQIYLQRRAERGTPK
TNIK_Hsap       ---------------------------------------IRASNPDLRRTEPILESPLQR
HGK_Hsap        ---------------------------------------NSTSSIEPRLLWERVEKLVPR
AqueK232_Aque   ------------------------------------------------------------


mig-15_Cele     NGN--GNSGHG------------------AYKGKKIP----EIRPGII------------
msn_Dmel        -LGQPVNPLDPLD-SSDSDSEPDEPNDRARNDG-TLLASDP-P--KPLPG----------
HGK_Mmus        PGS--GSSSGS------------------SNSG-SQP----GSHPGSQSGSGERFRV---
TNIK_Mmus       TSS--GSSSSS------------------STPS-SQPSSQGGSQPGSQAGSSERTRV---
MINK_Mmus       PPGPPAQPPGPPNASSNPDLRRSDPG-WERSDS-VLPASHG-H--LPQAGSLERNRV---
NRK_Mmus        RQR-S-SQN---------------------RQN-WLAASES--------SSEEESPVTGR
MSN_Spur        ------------------------------------------------NFKLDLTMA---
NRK_Hsap        RQR-S-SQN---------------------RQN-WLAASES--------SSEEESPVTGR
MINK_Hsap       PPGPPAQPPGPPNASSNPDLRRSDPG-WERSDS-VLPASHG-H--LPQAGSLERNRV---
TNIK_Hsap       TSS--GSSSSS------------------STPS-SQPSSQGGSQPGSQAGSSERTRV---
HGK_Hsap        PGS--GSSSGS------------------SNSG-SQP----GSHPGSQSGSGERFRV---
AqueK232_Aque   -----------------------------------K------------------------


mig-15_Cele     ------------------------------------------------------------
msn_Dmel        --------LGPVSEDAN-TTTPLSHGSGGPPNRPLP------------------------
HGK_Mmus        -RSSSKSEGSPSQRLENAVKKPEDKKE---VFRPLKPAG-----EVDLTALAKEL-----
TNIK_Mmus       -RANSKSEGSPVLPHEPAKVKPEESRD---ITRPSRPASYKKAIDEDLTALAKELRE--L
MINK_Mmus       -GVSSKPDSSPVLSPGN-KAKPDDHR-----SRPGRPASYKRAIGEDFV-LLKE-----R
NRK_Mmus        RSQSSPPYSTIDQKLLVDIHVPDGFKV----GK-ISPPVYLTNEWVGYNALSEIFRNDWL
MSN_Spur        -GHSAYVDSHHVLALALK-RRSQGHK-----SAK--------------------------
NRK_Hsap        RSQSSPPYSTIDQKLLVDIHVPDGFKV----GK-ISPPVYLTNEWVGYNALSEIFRNDWL
MINK_Hsap       -GVSSKPDSSPVLSPGN-KAKPDDHR-----SRPGRPASYKRAIGEDFV-LLKE-----R
TNIK_Hsap       -RANSKSEGSPVLPHEPAKVKPEESRD---ITRPSRPASYKKAIDEDLTALAKELRE--L
HGK_Hsap        -RSSSKSEGSPSQRLENAVKKPEDKKE---VFRPLKPAG-----EVDLTALAKEL-----
AqueK232_Aque   ----------P-------------------------------------------------


mig-15_Cele     ---------------------SLD-DDDSDSDN-EEGNEPLM----FKPIN---AS----
msn_Dmel        --------P--------------T---PDDDDQAGD------------------------
HGK_Mmus        RAVEDVRPPHKVTDYSSSSEESG-TTDEEDDDVEQEGADEST----SGPEDTRAAS----
TNIK_Mmus       RIEETNRPMKKVTDYSSSSEESE-SSEEEEEDGESETHDGTV----AVSDIPRLIP----
MINK_Mmus       TLDEAPRPPKKAMDYSSSSEEVE-SSEDDEEEGEGGPAEGSR--------DT--------
NRK_Mmus        TPAPVIQPPEEDGDYVELYDASA-DTDGDDDDESNDTFEDTYDHANGNDDLDNQVDQAND
MSN_Spur        ------------------------------------------------------------
NRK_Hsap        TPAPVIQPPEEDGDYVELYDASA-DTDGDDDDESNDTFEDTYDHANGNDDLDNQVDQAND
MINK_Hsap       TLDEAPRPPKKAMDYSSSSEEVE-SSEDDEEEGEGGPAEGSR--------DT--------
TNIK_Hsap       RIEETNRPMKKVTDYSSSSEESE-SSEEEEEDGESETHDGTV----AVSDIPRLIP----
HGK_Hsap        RAVEDVRPPHKVTDYSSSSEESG-TTDEEDDDVEQEGADEST----SGPEDTRAAS----
AqueK232_Aque   --------------------KTEDEDDDDDDDILGAAGD-TI----LT---TR-------


mig-15_Cele     ----------------------------------------------------------S-
msn_Dmel        ------------------------------------------------------------
HGK_Mmus        ----------------------------------------------------------SL
TNIK_Mmus       ----------------------------------------------------------TG
MINK_Mmus       ----------------------------------------------------------PG
NRK_Mmus        VCKDHDDDNNKFVDDVNNNYYEAPSCPRASYGRDGSCKQDGYDGSRGKEEAYRGYGSHTA
MSN_Spur        ------------------------------------------------------------
NRK_Hsap        VCKDHDDDNNKFVDDVNNNYYEAPSCPRASYGRDGSCKQDGYDGSRGKEEAYRGYGSHTA
MINK_Hsap       ----------------------------------------------------------PG
TNIK_Hsap       ----------------------------------------------------------TG
HGK_Hsap        ----------------------------------------------------------SL
AqueK232_Aque   ----------------------------------------------------------EQ


mig-15_Cele     ---------------------------------------------------------S--
msn_Dmel        ------------------------------------RTLIMKRNRGGGGGG-GGGGGGGG
HGK_Mmus        NLSNGET-ESVKTMIVHDDVESEP-----AMTPSKEGTLIVRQSTVDQKRA-SHH-ESNG
TNIK_Mmus       APGSNEQ-YNVGMVGTHGLETSHADSF--SGSISREGTLMIRETSGEKKRS-GHS-DSNG
MINK_Mmus       GRSDGDT-DSVSTMVVHDVEEITG-----TQPPYGGGTMVVQRTPEEERNL-LHA-DSNG
NRK_Mmus        NRSHGGSAASEDNAAIGDQEEHAANIGSERRGSEGDGGKGVVRTSEESGALGLNG-EENC
MSN_Spur        --------------------------------------FTFFDNTLLNKKL-LSK-DHNG
NRK_Hsap        NRSHGGSAASEDNAAIGDQEEHAANIGSERRGSEGDGGKGVVRTSEESGALGLNG-EENC
MINK_Hsap       GRSDGDT-DSVSTMVVHDVEEITG-----TQPPYGGGTMVVQRTPEEERNL-LHA-DSNG
TNIK_Hsap       APGSNEQ-YNVGMVGTHGLETSHADSF--SGSISREGTLMIRETSGEKKRS-GHS-DSNG
HGK_Hsap        NLSNGET-ESVKTMIVHDDVESEP-----AMTPSKEGTLIVRQSTVDQKRA-SHH-ESNG
AqueK232_Aque   GASDDFT-ASTDTKLSQYAEETLI-----IRPDSEPSSSFLQDSSPEQRKA---------


mig-15_Cele     R------------------G-ALPDLLPKSPQLRRQINDQTRQM----------------
msn_Dmel        SSGVGADGTGLGTPGTRTSS-VLPDLLSQAS-P-------------------------AT
HGK_Mmus        FAG---------------RIHLLPDLLQQSHSSSTSSTSSSPSSS-QPTP----TMSPQT
TNIK_Mmus       FAG---------------HIN-LPDLVQQSHSPAGTPTEGLGRVS-T-------------
MINK_Mmus       YT------------------N-LPDVVQPSHSPTENSKGQSPPS----------------
NRK_Mmus        ---SETDG---------------PGLKRPASQDFEYLQEEPGGGN-EASNAIDSGAAPSA
MSN_Spur        ES------------------N-LPRTSQESYGTSENGKGQLLPI----------------
NRK_Hsap        ---SETDG---------------PGLKRPASQDFEYLQEEPGGGN-EASNAIDSGAAPSA
MINK_Hsap       YT------------------N-LPDVVQPSHSPTENSKGQSPPS----------------
TNIK_Hsap       FAG---------------HIN-LPDLVQQSHSPAGTPTEGLGRVS-T-------------
HGK_Hsap        FAG---------------RIHLLPDLLQQSHSSSTSSTSSSPSSS-QPTP----TMSPQT
AqueK232_Aque   ---------------------------------------DQPFSSYQPSG----GAKP--


mig-15_Cele     ---SDDRADE--QPNGFQNSDSRSSI---------QHSFSNR----DREKSFVGYFGGGA
msn_Dmel        PPRHDKSSSEEKQR----------SFLT------------------------FGFGAGG-
HGK_Mmus        PQDKLTANETQSASSTLQKHKSSSSFTPFIDPRLLQISPSSG----TTVTSVVGFS----
TNIK_Mmus       -----HSQEMDSGTEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFT----
MINK_Mmus       ---KDGSGDY--QSRGLVKAPGKSSFTMFVDLGIYQPGGSG-----DSIPITALVG----
NRK_Mmus        P-DHESDNK------DISESSTQSDFSAN------HSSPSKG----SGMSADANFA----
MSN_Spur        ---RNGGSDY--RFKGLVRTKNMSSFTMFVSLMQHQPGSRG-----ETVNL-RLIG----
NRK_Hsap        P-DHESDNK------DISESSTQSDFSAN------HSSPSKG----SGMSADANFA----
MINK_Hsap       ---KDGSGDY--QSRGLVKAPGKSSFTMFVDLGIYQPGGSG-----DSIPITALVG----
TNIK_Hsap       -----HSQEMDSGTEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFT----
HGK_Hsap        PQDKLTANETQSASSTLQKHKSSSSFTPFIDPRLLQISPSSG----TTVTSVVGFS----
AqueK232_Aque   ------------------------------------------GGAV---PR---------


mig-15_Cele     GAGGGTVNRPGR---PQ-DINQ-VQ--VNVTPNSNGTPAENDAPEIRKYKKKFSGEILCA
msn_Dmel        ----------------SGPSRRESHVNVNVTPT--SHEAANDTPEIRKYKKRFNSEILCA
HGK_Mmus        --CDGM--RPEAI--RQDPTRKGSV--VNVNPT--NTRPQSDTPEIRKYKKRFNSEILCA
TNIK_Mmus       --SELL--RQEQA--KLNEARKISV--VNVNPT--NIRPHSDTPEIRKYKKRFNSEILCA
MINK_Mmus       --GEGT--RLDQL--QY-DVRKGSV--VNVNPT--NTRAHSETPEIRKYKKRFNSEILCA
NRK_Mmus        --SAIL--YAGFVEVPEESPKQPSE--VNVNPL--YVSPACKKPLIHMYEKEFTSEICCG
MSN_Spur        --GLAI--DLDQS--QF-LIRQSIS--VNVKPT--TPESLNDMPEIRKYRKKFNSEILCA
NRK_Hsap        --SAIL--YAGFVEVPEESPKQPSE--VNVNPL--YVSPACKKPLIHMYEKEFTSEICCG
MINK_Hsap       --GEGT--RLDQL--QY-DVRKGSV--VNVNPT--NTRAHSETPEIRKYKKRFNSEILCA
TNIK_Hsap       --SELL--RQEQA--KLNEARKISV--VNVNPT--NIRPHSDTPEIRKYKKRFNSEILCA
HGK_Hsap        --CDGM--RPEAI--RQDPTRKGSV--VNVNPT--NTRPQSDTPEIRKYKKRFNSEILCA
AqueK232_Aque   -----------PI--GASGGRQGEN--G--GVV--KAEVTKMNPEIRKYKRKFTSEILCG
                                    .:                     * *: *.:.*..** *.

mig-15_Cele     ALWGVNLLIGTDSGLMLLDRSGQGKVYPLISRRRFDQMTVLEGQNILATISGRKRRIRVY
msn_Dmel        ALWGVNLLIGTENGLMLLDRSGQGKVYQLISRRRFQQMEVLEGQNILVTISGKKNRVRVY
HGK_Mmus        ALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKDKLRVY
TNIK_Mmus       ALWGVNLLVGTENGLMLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLVTISGKKNKLRVY
MINK_Mmus       ALWGVNLLVGTENGLMLLDRSGQGKVYGLIGRRRFQQMDVLEGLNLLITISGKRNKLRVY
NRK_Mmus        SLWGVNLLLGTRSNLYLMDRSGKADITKLIRRRPFRQIQVLEPLNLLITISGHKNRLRVY
MSN_Spur        SLWGVNLLIGTDSGLMLLDRSGEGKVYPLISRKRFQQMDVLESQNILVCIAGKKNKLRTY
NRK_Hsap        SLWGVNLLLGTRSNLYLMDRSGKADITKLIRRRPFRQIQVLEPLNLLITISGHKNRLRVY
MINK_Hsap       ALWGVNLLVGTENGLMLLDRSGQGKVYGLIGRRRFQQMDVLEGLNLLITISGKRNKLRVY
TNIK_Hsap       ALWGVNLLVGTENGLMLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLVTISGKKNKLRVY
HGK_Hsap        ALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKDKLRVY
AqueK232_Aque   ALWGVNLLVGTDNGLMLLDRSGHGKVFPLISRRKFSQIDVLEGLNVLIGINGRKNKLRIY
                :*******:** ..* *:****...:  ** *: * *: ***  *:*  * *:: ::* *

mig-15_Cele     YLSWLRQKILRTEGAGSANTTEKRN--------GWVNVGDLQGAIHFKIVRYERIKFLVV
msn_Dmel        YLSWLKSKILRTDGLS--DQVERRN--------GWINVGDLQGAVHFKIVKYERIKFLVI
HGK_Mmus        YLSWLRNKILHNDPE-----VEKKQ--------GWTTVGDLEGCVHYKVVKYERIKFLVI
TNIK_Mmus       YLSWLRNRILHNDPE-----VEKKQ--------GWITVGDLEGCIHYKVVKYERIKFLVI
MINK_Mmus       YLSWLRNKILHNDPE-----VEKKQ--------GWTTVGDMEGCGHYRVVKYERIKFLVI
NRK_Mmus        HLTWLRNKILNNDPE-----SKRRQEEMLKTEEACKAIDKLTGCEHFSVLQHEETTYIAI
MSN_Spur        FLSWLKQKIVRSDGE-----AKRKS--------GFLSVGDLEGCIHYKIIKYEKIKFLVI
NRK_Hsap        HLTWLRNKILNNDPE-----SKRRQEEMLKTEEACKAIDKLTGCEHFSVLQHEETTYIAI
MINK_Hsap       YLSWLRNKILHNDPE-----VEKKQ--------GWTTVGDMEGCGHYRVVKYERIKFLVI
TNIK_Hsap       YLSWLRNRILHNDPE-----VEKKQ--------GWITVGDLEGCIHYKVVKYERIKFLVI
HGK_Hsap        YLSWLRNKILHNDPE-----VEKKQ--------GWTTVGDLEGCVHYKVVKYERIKFLVI
AqueK232_Aque   YLSWLKQKIMKHELD----SPHTRQ--------GFVPVGDLEHCVHYKVARSDKMKYLVI
                .*:**:.:*:. :        . :.        .   :..:  . *: : : :. .::.:

mig-15_Cele     GLESSIEIYAWAPKPYHKF-----------------------------------------
msn_Dmel        ALKDSIEIYAWAPKPYHKF-----------------------------------------
HGK_Mmus        ALKSSVEVYAWAPKPYHKF-----------------------------------------
TNIK_Mmus       ALKNAVEIYAWAPKPYHKF-----------------------------------------
MINK_Mmus       ALKSSVEVYAWAPKPYHKF-----------------------------------------
NRK_Mmus        ALKSSIHLYAWAPKSFDESTAIKVCIDQSADSEGDYMSYQAYIRILAKIQAADPVNRFKR
MSN_Spur        ALKDSIEIYAWAPKPYHKF-----------------------------------------
NRK_Hsap        ALKSSIHLYAWAPKSFDESTAIKVCIDQSADSEGDYMSYQAYIRILAKIQAADPVNRFKR
MINK_Hsap       ALKSSVEVYAWAPKPYHKF-----------------------------------------
TNIK_Hsap       ALKNAVEIYAWAPKPYHKF-----------------------------------------
HGK_Hsap        ALKSSVEVYAWAPKPYHKF-----------------------------------------
AqueK232_Aque   GTKTGVEVYAWAQRPYSKF-----------------------------------------
                . : .:.:**** :.: :

mig-15_Cele     -------MSFKSFGSLSHVPLIVDLTVEDNARLKVLYGSTGGFHAIDLDSAAVYDIYTPA
msn_Dmel        -------MAFKNFGELEHRPLLVDLTIEDQSRLKVIYGSAEGFHAVDLDSAEVYDIYLPK
HGK_Mmus        -------MAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPT
TNIK_Mmus       -------MAFKSFADLQHKPLLVDLTVEEGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPS
MINK_Mmus       -------MAFKSFADLPHRPLLVDLTVEEGQRLKVIYGSSAGFHAVDVDSGNSYDIYIPV
NRK_Mmus        PDELLHLLKLKVFPTLDHKPVTVDLAIGSEKRLKIFFSSADGYHLIDAESEVMSDVTLPK
MSN_Spur        -------MAFKSFPNLVHRPLIVDLTVEDNQRLKVIYGSVNGFHAIDLDSASVQDIYSPP
NRK_Hsap        PDELLHLLKLKVFPTLDHKPVTVDLAIGSEKRLKIFFSSADGYHLIDAESEVMSDVTLPK
MINK_Hsap       -------MAFKSFADLPHRPLLVDLTVEEGQRLKVIYGSSAGFHAVDVDSGNSYDIYIPV
TNIK_Hsap       -------MAFKSFADLQHKPLLVDLTVEEGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPS
HGK_Hsap        -------MAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPT
AqueK232_Aque   -------MAFKSFPDLPNKPILVDMVHMPGGKSKVVYASTSGFHAVDMDTGVVQNIYIPA
                       : :* *  * : *: **:.     : *:.:.*  *:* :* ::    ::  *

mig-15_Cele     QS--------GQTTTPHCIVVLPNSNGMQLLLCYDNEGVYVNTYGRMTKNVVLQWGEMPS
msn_Dmel        HT--------QGAIIPHCIVALPNSNGMQLLLCYDNEGVYVNTVGRVSKNIVLQWGEMPT
HGK_Mmus        HVRKNPHSMIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPT
TNIK_Mmus       HI--------QGNITPHAIVILPKTDGMEMLVCYEDEGVYVNTYGRITKDVVLQWGEMPT
MINK_Mmus       HI--------QSQITPHAIIFLPNTDGMEMLLCYEDEGVYVNTYGRIIKDVVLQWGEMPT
NRK_Mmus        NP--------LEIIIPQNIIILPDCLGIGMMLTFNAEALSVEANEQLFKKILEMWKDIPS
MSN_Spur        QE--------IGTITPYCVVILPNSQGKYLLLCFNNEGVFVDTKGVPFKDVILQWGELPA
NRK_Hsap        NP--------LEIIIPQNIIILPDCLGIGMMLTFNAEALSVEANEQLFKKILEMWKDIPS
MINK_Hsap       HI--------QSQITPHAIIFLPNTDGMEMLLCYEDEGVYVNTYGRIIKDVVLQWGEMPT
TNIK_Hsap       HI--------QGNITPHAIVILPKTDGMEMLVCYEDEGVYVNTYGRITKDVVLQWGEMPT
HGK_Hsap        HVRKNPHSMIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPT
AqueK232_Aque   AAA-------RGPILPHAIIPLPSK-PSELLLCHNNEGVYVDSEGRSTKDTRLQWGEEPS
                               *  :: **.     ::: .: *.: *::     *.    * : *:

mig-15_Cele     SVAYISTGQIMGWGNKAIEIRSVDTGHLDGVFMHKKAQKLKFLCERNDKVFFSSAKGGGS
msn_Dmel        SVAYIGTGQIMGWGNKAIEIRSVESGHLDGVFMHKKAQRLKFLCERNDKVFFSSAKGASS
HGK_Mmus        SVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGS
TNIK_Mmus       SVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGS
MINK_Mmus       SVAYICSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGS
NRK_Mmus        SIAFECTQRTTGWGQKAIEVRSLQSRVLESELKRRSIKKLRFLCTRGDKLFFTSTLRNHH
MSN_Spur        SVAYISTGQIMGWGNKAIEIRSAETGHLDGVFMHKRSQQLRFLCERNDKVFFASIRP-SN
NRK_Hsap        SIAFECTQRTTGWGQKAIEVRSLQSRVLESELKRRSIKKLRFLCTRGDKLFFTSTLRNHH
MINK_Hsap       SVAYICSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGS
TNIK_Hsap       SVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGS
HGK_Hsap        SVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGS
AqueK232_Aque   SVALIGESHVMGWGSKAIEIRAVESGQLDGVFMHKRTQKLRFLCERNDKVFFASIRSTSN
                *:*     :  ***.****:*: ::  *:. : ::  ::*:*** *.**:**:*

mig-15_Cele     CQIYFMTLNKPGL----TNW
msn_Dmel        CQIYFMTLNKPGM----ANW
HGK_Mmus        SQVYFMTLGRTSL----LSW
TNIK_Mmus       SQVFFMTLNRNSM----MNW
MINK_Mmus       SQVYFMTLNRNCI----MNW
NRK_Mmus        SRVYFMTLGKLEELQSNYDV
MSN_Spur        SQVYFLTLKRNCL------M
NRK_Hsap        SRVYFMTLGKLEELQSNYDV
MINK_Hsap       SQVYFMTLNRNCI----MNW
TNIK_Hsap       SQVFFMTLNRNSM----MNW
HGK_Hsap        SQVYFMTLGRTSL----LSW
AqueK232_Aque   SQVYFMALNRSLVPSSSSSS
                .:::*::* :