PRP4_Hsap ------------------------------------------------------------
PRP4_Mmus ------------------------------------------------------------
F22D6.5_Cele ------------------------------------------------------------
Prp4_Ddis ------------------------------------------------------------
15575_Tthe KQ---------KKKEDGELSGEEDEYKSPKQKKSDKDDRKKSKRSSRSHSS-RR------
PRP4_Spur K---------HKHK------SKKSHHKHKHH-KENKDGHRRHKHKHKKHKS-KK------
CG7028_Dmel ------------------------------------------------------------
CC1G_04865_Ccin ------------------------------------------------------------
AqueK115_Aque ------------------------------------------------------------
AqueK116_Aque ------------------------------------------------------------
PRP4_e_Smoe ------------------------------------------------------------
PRP4_d_Smoe ------------------------------------------------------------
PRP4_b_Smoe ------------------------------------------------------------
PRP4_a_Smoe GRVDDAKDKSRKRK------SVEDEQPSSKR-REDDDGKRKHKHRKHKHRSSHRKHISKE
PRP4_c_Smoe ------------------------------------------------------------
PRP4_Hsap ------------------------------------------------------------
PRP4_Mmus ------------------------------------------------------------
F22D6.5_Cele ------------------------------------------------------------
Prp4_Ddis ------------------------------------------------------------
15575_Tthe TNDKISDSTK--------------------------------------------------
PRP4_Spur DEEPP---------------------VATPAADESESDIELEDTIPLPKFEPKIPPPPPP
CG7028_Dmel ------------------------------------------------------------
CC1G_04865_Ccin ------------------------------------------------------------
AqueK115_Aque ------------------------------------------------------------
AqueK116_Aque ------------------------------------------------------------
PRP4_e_Smoe ------------------------------------------------------------
PRP4_d_Smoe ------------------------------------------------------------
PRP4_b_Smoe ------------------------------------------------------------
PRP4_a_Smoe VDLDVVPAAMACEAEDGEILEPTEDGI---------------------------------
PRP4_c_Smoe ------------------------------------------------------------
PRP4_Hsap ------------------------------------------------------------
PRP4_Mmus ------------------------------------------------------------
F22D6.5_Cele ------------------------------------------------------------
Prp4_Ddis ------------------------------------------------------------
15575_Tthe --------------------------------------------------SNKKDKD---
PRP4_Spur PNSRRESGRKERGRGGDDTLAALEKQKELLQAQLLATAEDEHSGMNLIAQGYQSDEEEGE
CG7028_Dmel ------------------------------------------------------------
CC1G_04865_Ccin ------------------------------------------------------------
AqueK115_Aque ------------------------------------------------------------
AqueK116_Aque ------------------------------------------------------------
PRP4_e_Smoe ------------------------------------------------------------
PRP4_d_Smoe ------------------------------------------------------------
PRP4_b_Smoe ------------------------------------------------------------
PRP4_a_Smoe ---------------------------------------------VLKE-----------
PRP4_c_Smoe ------------------------------------------------------------
PRP4_Hsap ------------------------------------------------------------
PRP4_Mmus ------------------------------------------------------------
F22D6.5_Cele ------------------------------------------------------------
Prp4_Ddis ------------------------------------------------------------
15575_Tthe ----------------HKDSSRRRSKSRSKDRKDQQKRKYS---------RSRSRSYPND
PRP4_Spur DDESALKQSLSKWIRPESSSSKPSSKSELKDSERSEKRKREREDETSQKKQHRSKSPATE
CG7028_Dmel ------------------------------------------------------------
CC1G_04865_Ccin ------------------------------------------------------------
AqueK115_Aque ------------------------------------------------------------
AqueK116_Aque ------------------------------------------------------------
PRP4_e_Smoe ------------------------------------------------------------
PRP4_d_Smoe ------------------------------------------------------------
PRP4_b_Smoe ------------------------------------------------------------
PRP4_a_Smoe ----------------EGNGSSESEKDV----------EQEIE-----------------
PRP4_c_Smoe ------------------------------------------------------------
PRP4_Hsap ------------------------------------------------------------
PRP4_Mmus ------------------------------------------------------------
F22D6.5_Cele ------------------------------------------------------------
Prp4_Ddis ------------------------------------------------------------
15575_Tthe RNGTKQRHLDNLYQRTQIKNGKCNQIYGSQKRNTKFSNDKFLFSNSKNLSEAFYIDSYFY
PRP4_Spur RSSGS----------SRVDNGDAKSSQSRTNRDSHIASDRKHSKDSDSRRDSRKSSPSAT
CG7028_Dmel ------------------------------------------------------------
CC1G_04865_Ccin ------------------------------------------------------------
AqueK115_Aque ------------------------------------------------------------
AqueK116_Aque ------------------------------------------------------------
PRP4_e_Smoe ------------------------------------------------------------
PRP4_d_Smoe ------------------------------------------------------------
PRP4_b_Smoe ------------------------------------------------------------
PRP4_a_Smoe -------------------------------------------------------APKSE
PRP4_c_Smoe ------------------------------------------------------------
PRP4_Hsap ------------------------------------------------------------
PRP4_Mmus ------------------------------------------------------------
F22D6.5_Cele ------------------------------------------------------------
Prp4_Ddis ------------------------------------------------------------
15575_Tthe SLNSSKKDKDRDNAKEKDRKR------SKSPTKDKDRKNDRK-RSKSPRSSNNGK-----
PRP4_Spur KSEQRESRDSREPRDSR--KSSGRDGRASPKRELKSGEKSRRESSRDSKPIRSRSPKKER
CG7028_Dmel ------------------------------------------------------------
CC1G_04865_Ccin ------------------------------------------------------------
AqueK115_Aque ------------------------------------------------------------
AqueK116_Aque ------------------------------------------------------------
PRP4_e_Smoe ------------------------------------------------------------
PRP4_d_Smoe ------------------------------------------------------------
PRP4_b_Smoe ------------------------------------------------------------
PRP4_a_Smoe RGSPRRSRDGSPPRDNVDRKH------SSPDRRHRGSSVDRKRRSRSKESVRENA-----
PRP4_c_Smoe ------------------------------------------------------------
PRP4_Hsap ------------------------------------------------------------
PRP4_Mmus ------------------------------------------------------------
F22D6.5_Cele ------------------------------------------------------------
Prp4_Ddis ------------------------------------------------------------
15575_Tthe ---------------------------------------------------------RKS
PRP4_Spur VFTEPARSRPSPPRRSPPPRRPPSPPARRPDQPLGRRGRSPIERRGRSPLERRIRSSRSP
CG7028_Dmel ------------------------------------------------------------
CC1G_04865_Ccin ------------------------------------------------------------
AqueK115_Aque ------------------------------------------------------------
AqueK116_Aque ------------------------------------------------------------
PRP4_e_Smoe ------------------------------------------------------------
PRP4_d_Smoe ------------------------------------------------------------
PRP4_b_Smoe ------------------------------------------------------------
PRP4_a_Smoe ---------------------------------------------------------RHH
PRP4_c_Smoe ------------------------------------------------------------
PRP4_Hsap ------------------------------------------------------------
PRP4_Mmus ------------------------------------------------------------
F22D6.5_Cele ------------------------------------------------------------
Prp4_Ddis ------------------------------------------------------------
15575_Tthe SRSKSPKREDSRRDKDSKSGYRDNEKKSNYGSNRDRESRRSEEN-----NTRESKQLTLE
PRP4_Spur AVVDRFDRRRGASPPRRFGDMSRNRRRWSRSPDRRGR-R-GRWGRSRSKS----------
CG7028_Dmel ------------------------------------------------------------
CC1G_04865_Ccin ------------------------------------------------------------
AqueK115_Aque ------------------------------------------------------------
AqueK116_Aque ------------------------------------------------------------
PRP4_e_Smoe ------------------------------------------------------------
PRP4_d_Smoe ------------------------------------------------------------
PRP4_b_Smoe ------------------------------------------------------------
PRP4_a_Smoe SRVASPDRKRRRSRSRDRGDE-R-SRRHAYSPDRRRRSR-SREHDEREKY----------
PRP4_c_Smoe ------------------------------------------------------------
PRP4_Hsap ------------------------------------------------------------
PRP4_Mmus ------------------------------------------------------------
F22D6.5_Cele ------------------------------------------------------------
Prp4_Ddis ------------------------------------------------------------
15575_Tthe EEEERNDRYYNDFDDSDSDYYQRVNDRKYKSSRRSKS------------RSKNRDRKKSK
PRP4_Spur ----------------------------------PRDKFKGSLSEGLSLKQESSDDEIPD
CG7028_Dmel ------------------------------------------------------------
CC1G_04865_Ccin ------------------------------------------------------------
AqueK115_Aque ------------------------------------------------------------
AqueK116_Aque ------------------------------------------------------------
PRP4_e_Smoe ------------------------------------------------------------
PRP4_d_Smoe ------------------------------------------------------------
PRP4_b_Smoe ------------------------------------------------------------
PRP4_a_Smoe ----------------------------------PRK------------RAESRDRHIKD
PRP4_c_Smoe ------------------------------------------------------------
PRP4_Hsap ------------------------------------------------------------
PRP4_Mmus ------------------------------------------------------------
F22D6.5_Cele ------------------------------------------------------------
Prp4_Ddis ------------------------------------------------------------
15575_Tthe SKGRKDD-KNKDKDKER---SKNSGNGDNSKSSKDKKEEEAKKAQQPETIDDDE------
PRP4_Spur VDLDEEEDEEAVIERRRR------------------------------------------
CG7028_Dmel ------------------------------------------------------------
CC1G_04865_Ccin ------------------------------------------------------------
AqueK115_Aque ------------------------------------------------------------
AqueK116_Aque ------------------------------------------------------------
PRP4_e_Smoe ------------------------------------------------------------
PRP4_d_Smoe ------------------------------------------------------------
PRP4_b_Smoe ------------------------------------------------------------
PRP4_a_Smoe DRGARDDERHYNRDRNRRDREELSE---------------KQETTQSETIEREEENQDEY
PRP4_c_Smoe ------------------------------------------------------------
PRP4_Hsap ------------------------------------------------------------
PRP4_Mmus ------------------------------------------------------------
F22D6.5_Cele ------------------------------------------------------------
Prp4_Ddis ------------------------------------------------------------
15575_Tthe ---------DLNMEIEDSDDERERKKQEFLNMIKVQGM----------------------
PRP4_Spur ------------------------ERQQLMQKYKVAPAESATSSPAQGPSEPSSTPQSPQ
CG7028_Dmel ------------------------------------------------------------
CC1G_04865_Ccin ------------------------------------------------------------
AqueK115_Aque ------------------------------------------------------------
AqueK116_Aque ------------------------------------------------------------
PRP4_e_Smoe ------------------------------------------------------------
PRP4_d_Smoe ------------------------------------------------------------
PRP4_b_Smoe ------------------------------------------------------------
PRP4_a_Smoe LERVAHQLAEQEEDIEKVKEESRKRRQAI-------------------------------
PRP4_c_Smoe ------------------------------------------------------------
PRP4_Hsap ------------------------------------------------------------
PRP4_Mmus ------------------------------------------------------------
F22D6.5_Cele ------------------------------------------------------------
Prp4_Ddis ------------------------------------------------------------
15575_Tthe ------------------------------------------------------------
PRP4_Spur ASEQGGSTAQSQDTDDEDDDEEEEEEDEEEDDSEKSSSSDSDDDSSEVESKASSDDDDDD
CG7028_Dmel ------------------------------------------------------------
CC1G_04865_Ccin ------------------------------------------------------------
AqueK115_Aque ------------------------------------------------------------
AqueK116_Aque ------------------------------------------------------------
PRP4_e_Smoe ------------------------------------------------------------
PRP4_d_Smoe ------------------------------------------------------------
PRP4_b_Smoe ------------------------------------------------------------
PRP4_a_Smoe ------------------------------------------------------------
PRP4_c_Smoe ------------------------------------------------------------
PRP4_Hsap ------------------------------------------------------------
PRP4_Mmus ------------------------------------------------------------
F22D6.5_Cele ------------------------------------------------------------
Prp4_Ddis ------------------------------------------------------------
15575_Tthe --------------------------------------QMQKQEASQTFSKENNQNNQTQ
PRP4_Spur EEDDEGDAARIEEEERLREEEEEAEQEKRREMERKRLKE---------------------
CG7028_Dmel ------------------------------------------------------------
CC1G_04865_Ccin ------------------------------------------------------------
AqueK115_Aque ------------------------------------------------------------
AqueK116_Aque ------------------------------------------------------------
PRP4_e_Smoe ------------------------------------------------------------
PRP4_d_Smoe ------------------------------------------------------------
PRP4_b_Smoe ------------------------------------------------------------
PRP4_a_Smoe -------------------------------LEKHKMQQ---------------------
PRP4_c_Smoe ------------------------------------------------------------
PRP4_Hsap ------------------------------------------------------------
PRP4_Mmus ------------------------------------------------------------
F22D6.5_Cele ------------------------------------------------------------
Prp4_Ddis ------------------------------------------------------------
15575_Tthe NKNDQDVVDDKLKVKDSENLENQNFADENSEEQLFDDTGLNPNDVLDDDDVNIANTINDD
PRP4_Spur ------------------------------------------------------------
CG7028_Dmel ------------------------------------------------------------
CC1G_04865_Ccin ------------------------------------------------------------
AqueK115_Aque ------------------------------------------------------------
AqueK116_Aque ------------------------------------------------------------
PRP4_e_Smoe ------------------------------------------------------------
PRP4_d_Smoe ------------------------------------------------------------
PRP4_b_Smoe ------------------------------------------------------------
PRP4_a_Smoe ------------------------------------------------------------
PRP4_c_Smoe ------------------------------------------------------------
PRP4_Hsap ------------------------------------------------------------
PRP4_Mmus ------------------------------------------------------------
F22D6.5_Cele ------------------------------------------------------------
Prp4_Ddis ------------------------------------------------------------
15575_Tthe YKEEVDESHSLTHRHSIDKAQLDHLKFLEDMRNQEIKGGIPDMPEQPILKQKRKSINSEK
PRP4_Spur ------------------------------------------------------------
CG7028_Dmel ------------------------------------------------------------
CC1G_04865_Ccin ------------------------------------------------------------
AqueK115_Aque ------------------------------------------------------------
AqueK116_Aque ------------------------------------------------------------
PRP4_e_Smoe ------------------------------------------------------------
PRP4_d_Smoe ------------------------------------------------------------
PRP4_b_Smoe ------------------------------------------------------------
PRP4_a_Smoe ------------------------------------------------------------
PRP4_c_Smoe ------------------------------------------------------------
PRP4_Hsap ------------------------------------------------------------
PRP4_Mmus ------------------------------------------------------------
F22D6.5_Cele ------------------------------------------------------------
Prp4_Ddis ------------------------------------------------------------
15575_Tthe LEGKFSNNDQLD-----EENKLHK------------------------------------
PRP4_Spur ---AFPQSDSED-----EESAANSKKGEGSLDKN----------------------LSDI
CG7028_Dmel ------------------------------------------------------------
CC1G_04865_Ccin ------------------------------------------------------------
AqueK115_Aque ------------------------------------------------------------
AqueK116_Aque ------------------------------------------------------------
PRP4_e_Smoe ------------------------------------------------------------
PRP4_d_Smoe ------------------------------------------------------------
PRP4_b_Smoe ------------------------------------------------------------
PRP4_a_Smoe ---SQPEEPAETMKVSKPLTAAEPDSGEGIIDPSTPLSLGKSALPNGTILKRNAGGLGEG
PRP4_c_Smoe ------------------------------------------------------------
PRP4_Hsap ------------------------------------------------------------
PRP4_Mmus ------------------------------------------------------------
F22D6.5_Cele ------------------------------------------------------------
Prp4_Ddis ------------------------------------------------------------
15575_Tthe -----LDDQEDSEEETDMF------GDDIDKIINKSNDG--KLQI-VKGANAECDDEQNY
PRP4_Spur VKPKSDKEQAMANNGLDMFSEVDMFKMSP-----STREGIGQMGPENPSLTDNWDDEEGY
CG7028_Dmel ------------------------------------------------------------
CC1G_04865_Ccin ------------------------------------------------------------
AqueK115_Aque ------------------------------------------------------------
AqueK116_Aque ------------------------------------------------------------
PRP4_e_Smoe ------------------------------------------------------------
PRP4_d_Smoe ------------------------------------------------------------
PRP4_b_Smoe ------------------------------------------------------------
PRP4_a_Smoe SPPKSEK-------PADMFC--DIFGESPAEIRKAGTRD--TLAIDTSGLTDNWDDADGY
PRP4_c_Smoe ------------------------------------------------------------
PRP4_Hsap ------------YNVYGYTGQGVFSNVVRARDNA--------------RANQEVAVKIIR
PRP4_Mmus ------------YNVYGYTGQGVFSNVVRARDNA--------------RANQEVAVKIIR
F22D6.5_Cele ------------YRVVGFTGAGVFGNVCRCNDQT--------------KG-NTVAVKIIR
Prp4_Ddis ------------YQIFSPIGSGVFSTVVSAKETKT---------------NEDVVIKIIR
15575_Tthe FKILIGEVLNGKYRVIQKCGKGVFANVCKAEQLDN---------------GKMVAIKILR
PRP4_Spur YRVRIGESLDKRYAVYGYTGQGVFSNVVRARDTA--------------RGKLDVAIKIIR
CG7028_Dmel ------------YLVNGYTGQGVFSNVVRGRDQA--------------RGQANVAIKIIR
CC1G_04865_Ccin ------------YQVFSSLGQGMFANVVRARVLKDENGKDLAVDGVAPESLREVAIKIIR
AqueK115_Aque ------------YMVYGYTGQGVFSNVVRARDTS--------------RSSQEVAIKIIR
AqueK116_Aque ------------YMVYGYTGHGVFSNVVRARDTS--------------RSSQEVAIKIIR
PRP4_e_Smoe ------------YQVKASIGSGMFSTVFLAKSLFP-------------ECEQEVAIKIPR
PRP4_d_Smoe ------------YQVKASIGSGMFSTVFLAKSLLP-------------ECQQEVAIKIPR
PRP4_b_Smoe ------------YEIASSHGRGVFSTVVRARDTKAGRG-----------EPEEVAIKIIR
PRP4_a_Smoe YTYRVGEVLDNRYEIASSHGRGVFSTVVRARDTKAGRG-----------EPEEVAIKIIR
PRP4_c_Smoe ------------------------------------------------------------
PRP4_Hsap NNELMQKTGLKELEFLKKLNDA--DPDDK-FHCLRLFRHFYHKQHLCLVFEPLSMNLREV
PRP4_Mmus NNELMQKTGLKELEFLKKLNDA--DPDDK-FHCLRLFRHFYHKQHLCLVFEPLSMNLREV
F22D6.5_Cele NNEVMYKTGLRELEVLRKLNEA--DKEDK-YHCLRLFRTFKHHNHLCLVFENLSMNLREL
Prp4_Ddis NRPSMHRSGLKEIEILQKISNTPTSSNQK-SHCIQMKDHFNYRNHLCIVFEPMSMSLHQL
15575_Tthe SNEIMRDSGEREKEIIQKLNLN--DKNDR-KHIVRLKNVFEHQKHMCLVFECFAMNLRDA
PRP4_Spur NNDLMQKTGMKELEYLKRLNDQ--DREDK-FHCVRLFRSFSYRQHLCLVFEPLSMNLREV
CG7028_Dmel NNEIMHKTGLRELEILKKLNDA--DPEDR-FHCLRLYRHFFHKQHLCMVFEPLAMNLREV
CC1G_04865_Ccin SQESMYKAGLKEAQILQKLRAL--DPEDK-KHIVKLERTFEHRGHLCLVFENLSMNLREV
AqueK115_Aque NNEMMHKTGMAELEILKKLNAT--DPDDK-FHCIRLFSNFFHKNHLCLVFESMSMNIREV
AqueK116_Aque NNEMMHKTGMAELEILKKLNAT--DPDDK-FHCIRLFSNFFHKNHLCLVFESMSMNIREV
PRP4_e_Smoe KNDLMLRSAKSELQILKKVAEP--EATNKDNHCVKLLDSFVYREHLCLVMESLDLNLRQI
PRP4_d_Smoe KNDLMLRSAKSELQILKKVAEP--EATNKDNHCVKLLDSFVYREHLCLVMEFLDLNLRQI
PRP4_b_Smoe SNETMFKAGQMELIILNKLAGA--DLENK-RHCVRLLSSFEYRNHLCLVFESLHMNLREI
PRP4_a_Smoe SNETMFKAGQMELIILNKLAGA--DLENK-RHCVRLLSSFEYRNHLCLVFESLHMNLREI
PRP4_c_Smoe -------------------------------------------EHLCLVMESLDLNLRQI
*:*:*:* : :.:::
PRP4_Hsap LKKYGKDVGLHIKAVRSYSQQLFLALKLLKRCNILHADIKPDNILVNESKTILKLCDFGS
PRP4_Mmus LKKYGKDVGLHIKAVRSYSQQLFLALKLLKRCNILHADIKPDNILVNESKTILKLCDFGS
F22D6.5_Cele LKKYGQKDGLHLKAVRSYAQQLLLALRLLKKLEFVHADIKPDNILVNESKLTLKLCDFGS
Prp4_Ddis IKKYGKDIGLSLNAVRVYAKQLFLALKHIKNSKILHADIKPDNIVVNEAKNTIKIVDFGS
15575_Tthe LKEYGKGKGFSLDVVRSYAYQIFVALTHLKKNNYIHADLKPDNLLISEDTKTLKMCDFGT
PRP4_Spur LKRYGKDVGLHIKAVRSYTQQLFLALKLLKRCNILHADIKPDNILVNESKSVLKLCDFGS
CG7028_Dmel LKKYGKNVGLHIKAVRSYTQQLFLALKLLKKTGILHADIKPDNILVNENNLILKLCDFGS
CC1G_04865_Ccin VKRFGKDVGLNIRAVRAYAHQLFLALSLLRKANIMHADIKPDNILVNEQKNLIKLCDLGS
AqueK115_Aque LRKYGKNIGLHIKAVRSYSQQLLLALKLMKRCTILHADIKPDNILVNESKLMLKLCDFGS
AqueK116_Aque LRKYGKNIGLHIKAVRSYSQQLLLALKLMKRCTILHADIKPDNILVNESKLMLKLCDFGS
PRP4_e_Smoe TNKYGRNRGINLKTICVYAHQLMVALQHLAHCGILHCDIKPDNIMVTKSRRSIKLCDFGV
PRP4_d_Smoe TNKYGRNRGINLKTICVYAHQLMVALQHLAHCGILHCDIKPDNIMVTKSRRSIKLCDFGV
PRP4_b_Smoe LKKFGRNIGISLAAVRSYARQLFTALKHLRNCGVLHCDIKPDNMLVNDSKNLLKLCDFGS
PRP4_a_Smoe LKKFGRNIGISLAAVRSYARQLFTALKHLRNCGVLHCDIKPDNMLVNDSKNLLKLCDFGS
PRP4_c_Smoe TNKYGRNRGINLKTICVYAHQLMVALQHLAHCGIFHCDIKPDNIMVTKSRRSIKLCDFGV
..:*: *: : .: *: *:: ** : . .*.*:****:::.. :*: *:*
PRP4_Hsap ASHVADN---DITPYLVSRFYRAPEIIIGK-SYDYGIDMWSVGCTLYELYTGKILFPGKT
PRP4_Mmus ASHVADN---DITPYLVSRFYRAPEIIIGK-SYDYGIDMWSVGCTLYELYTGKILFPGKT
F22D6.5_Cele AGRVNEQ---ELAPYLVSRFYRAPEIMLGV-RHDYAIDLWSVAVTLYEVYTGKIMFPGRT
Prp4_Ddis AGEIHES---EITPYLVSRFYRAPEIILGH-KYDYSIDVWSVGCCLAEFFTGKFLFPGKT
15575_Tthe ALPIEEN---GIIKYLQSRFYRAPEVLIGY-PPYNQIDVWSVGVTLYEIYTQKILFDGST
PRP4_Spur ASHVADN---DITPYLVSRFYRAPEIIIGM-NYDAAIDMWSTGCTIFELAAGKIMFPGKT
CG7028_Dmel ASAISDN---EITPYLVSRFYRSPEIILGI-PYDYGIDTWSAGCTIYELYTGKILFSGKS
CC1G_04865_Ccin ASDASEN---EITPYLVSRFYRAPEIILGV-PYDPALDVWSIGCTLYELYTGKILFPGRS
AqueK115_Aque ASFIQDN---EITPYLVSRFYRAPE-----------------------------------
AqueK116_Aque ASFIQDN---EITPYLVSRFYRAPEIIIGC-KYDYGIDMWSVGATLYELYTGQILFPGKS
PRP4_e_Smoe AMFARDQTPSAETPYLVSPSYRAPEIILGVAPYSHAIDMWSAGCCLYELYTGKFLFPVAT
PRP4_d_Smoe AMFARDQTPSAETPYLVSPSYRAPEIILGVAPYSHPIDMWSAGCCLYELYTGKFLFPVAT
PRP4_b_Smoe AMFAGEN---EITPYLVSRFYRAPEIILGL-PYDHALDMWSVGCCLYELYTGKVLFPGST
PRP4_a_Smoe AMFAGEN---EITPYLVSRFYRAPEIILGL-PYDHALDMWSVGCCLYELYTGKVLFPGST
PRP4_c_Smoe AMFARDQTPSAETPYLVSPSYRAPEIILGVAPYSHQIDMWSAGCCLYELYTGKFLFPVAT
* :. ** * **:**
PRP4_Hsap NNHMLKLAMDLKGKMPNKMIRKGVFKDQHFDQNLNFMYIEVDKVTEREK-----------
PRP4_Mmus NNHMLKLAMDLKGKMPNKMIRKGVFKDQHFDQNLNFMYIEVDKVTEREK-----------
F22D6.5_Cele NNHMLKLFTDVKGKYPNKLVRKSQFKDTHFDVNCNLLYQEVDKVTERNK-----------
Prp4_Ddis NNDMIRLFMEYRGAFSKKMLKKSEFVSNHFNENLVFMKQEIDNIEKTVR-----------
15575_Tthe NNEMLKLIMDSRGKFNKKMLQNGKYVEEYFDQNYNFKYTYVDKQTNQKY-----------
PRP4_Spur NNHMLKLFMDLKGKMPHKIIRKGILRDKHFDPNCNFKYVEVDKVTEREK-----------
CG7028_Dmel NNQMLKFFMDVKGKIPNRII----------------------------------------
CC1G_04865_Ccin NNQMLRLMMELKGRFNTKIIKKAKFGETYFDELGAFESVERDRLTGSDI-----------
AqueK115_Aque ------------------------------------------------------------
AqueK116_Aque NNEMLKLNMELKGKMSHKMVRKGMFRENHFDSSFNFLYHTVDKVTQKEK-----------
PRP4_e_Smoe NNGLLKQQMELKGAFPKAMLKKGAFTGMHFNENFEF--RQLDPVTKLET-----------
PRP4_d_Smoe NNGLLKQQMELKGAFPKAMLKKGAFTGMHFNENFEF--RQLDPVTKLET-----------
PRP4_b_Smoe NNDMLRLHMELKGPFPKKMLRKAMFTAQHFDQDLNFHAIEEDPVTKKTI-----------
PRP4_a_Smoe NNDMLRLHMELKGPFPKKMLRKAMFTAQHFDQDLNFHAIEEDPVTKKVQFCIFPVYSFLH
PRP4_c_Smoe NNGLLKQQMELKGAFPKAMLKKGAFTGMHFNENFEF--RQLDPVTKLET-----------
PRP4_Hsap -------VTVMSTIN-PTKDLLADLIGCQ--RLPEDQRKKVHQLKDLLDQILMLDPAKRI
PRP4_Mmus -------VTVMSTIN-PTKDLLADLIGCQ--RLPEDQRKKVHQLKDLLDQILMLDPAKRI
F22D6.5_Cele -------ITVLANLK-PTRDLESELIAGQ--RLSRDQMDQIQAFRTLLDGMLILDPSKRT
Prp4_Ddis -------KVPHDITK-PTKDILQFLLPKN-VSIPDQDMKKLIQLKDLIEKCTILDPEKRI
15575_Tthe -------TTIITYGDIPKKDIYRLLQEN-KDGINLENQKKLSQFKDFLDKCLQLDPKNRI
PRP4_Spur -------VTVMTVIN-PTKDLTTELLGYQ--RLPEDQQRKVLQLKDVLDRCLMLDPSKRI
CG7028_Dmel ----------------------------------------VTQLKDLLENMFALDPAKRI
CC1G_04865_Ccin -------TRKIHIQK-PTRDLRARLMPSSSVKLNDEETKMLANFIDLLDKCLMLDPARRI
AqueK115_Aque ------------------------------------------------------------
AqueK116_Aque -------VVVMSSFS-PQRDLLADLVGSQ--SPSEAHLRKIHHFKDFLDKIFILDPTKRL
PRP4_e_Smoe -------LRSMASFN-VKTSCISDLTG--------EDGALMARFKNLLERMLTLDPSKRI
PRP4_d_Smoe -------LRSMASFN-VKTSCISDLTG--------EDGALMARFKNLLERMLTLDPSKRI
PRP4_b_Smoe -------NRMITNVK-P-KDI-STLISSS--GGSDEDAKNLLNFKLLLEKIFILDPEKRL
PRP4_a_Smoe LLSFQTINRMITNVK-P-KDI-STLISSS--GGSDEDAKNLLNFKLLLEKIFILDPEKRL
PRP4_c_Smoe -------LRSMASFN-VKTSCLSDLTG--------EDGALMSRFKNLLERMLTLDPSKRI
PRP4_Hsap SINQAL----Q
PRP4_Mmus SINQAL----Q
F22D6.5_Cele TCNEALKHPFF
Prp4_Ddis TPFEA-----L
15575_Tthe TPEEALEHPFL
PRP4_Spur SINEVLRHSFI
CG7028_Dmel SLNQALVHPFI
CC1G_04865_Ccin TPREALSHPFI
AqueK115_Aque ----------I
AqueK116_Aque SINQALQHPFI
PRP4_e_Smoe TPDEALKHPFL
PRP4_d_Smoe TPDEALKHPFL
PRP4_b_Smoe TVSQALNHPFI
PRP4_a_Smoe TVSQALNHPFI
PRP4_c_Smoe TPDEALKHPFL