Kinase Glossary: ePK
ePK stands for eukaryotic Protein Kinase. Most eukaryotic protein kinases belong to this superfamily. ePKs themselves are part of the PKL or Protein Kinase-Like fold, and share a common protein fold and catalytic mechanism. ePKs have a number of specific characteristics, including more elaborate regulatory mechanisms , and are exclusively protein kinases, while other PKLs also phosphorylate various small molecules.
Human kinases have been classified into typical ePKs and Atypical kinases  that include both other PKLs and other kinase types. More recently , several typical kinases have been split off into other PKL classes, such as Bub, Haspin, and Bud32.
See also: Protein Kinase Evolution
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