View source for Kinase Family STE11

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[[kinase classification|Kinase Classification]]: [[Kinase_Group_STE|Group STE]]: [[Kinase_Family_STE11|Family STE11]]

STE11 (MAP3K, MEKK) kinases are part of the MAPK signaling cascades: they are activated by [[Kinase_Family_STE20|STE20]] (MAP4K) and phosphorylate [[Kinase_Family_STE7|STE7]] (MAP2K, MEK) kinases.

The STE11 family has the following subfamilies: 

====[[Kinase_Subfamily_MEKK1|MEKK1]]====

====[[Kinase_Subfamily_MEKK2|MEKK2]]====

====[[Kinase_Subfamily_MEKK4|MEKK4]]====

====[[Kinase_Subfamily_MEKK15|MEKK15]]====

====[[Kinase_Subfamily_ASK|ASK]]====

====[[Kinase_Subfamily_CDC15|CDC15]]====


====Evolution====
STE11 kinases are found in almost all eukaryotes, with Plasmodium being a notable exception.