Difference between revisions of "E91"

From WikiKinome
Jump to: navigation, search
m
Line 2: Line 2:
 
[[Kinase Glossary]]: [[E91]]
 
[[Kinase Glossary]]: [[E91]]
  
[[E91]] is a key conserved residue in [[ePK]] and most [[PKL]] kinases. It forms a salt bridge with [[K72]]. It is found in the C helix, though it is not part of a larger motif, making it difficult to detect in some remote kinases. The number 91 is based on the position of this residue in the first PKA kinase crystal. It is a D in some PKL kinases.
+
[[E91]] is a key conserved residue in [[ePK]] and most [[PKL]] kinases. It forms a salt bridge with [[K72]]. It is found in the C helix, though it is not part of a larger motif, making it difficult to detect in some remote kinases. The number 91 is based on the position of this residue in the first PKA kinase crystal <cite>taylor1991</cite>. It is a D in some PKL kinases.
 +
 
 +
<biblio>
 +
#taylor1991 pmid=1862342
 +
</biblio>

Revision as of 18:35, 13 May 2014

Kinase Glossary: E91

E91 is a key conserved residue in ePK and most PKL kinases. It forms a salt bridge with K72. It is found in the C helix, though it is not part of a larger motif, making it difficult to detect in some remote kinases. The number 91 is based on the position of this residue in the first PKA kinase crystal [1]. It is a D in some PKL kinases.

  1. Knighton DR, Zheng JH, Ten Eyck LF, Ashford VA, Xuong NH, Taylor SS, and Sowadski JM. Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase. Science. 1991 Jul 26;253(5018):407-14. DOI:10.1126/science.1862342 | PubMed ID:1862342 | HubMed [taylor1991]