Difference between revisions of "Kinase Family LISK"
From WikiKinome
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The LISK family consists of two main subfamilies: | The LISK family consists of two main subfamilies: | ||
| − | ====[[Kinase_Subfamily_LIMK|LIMK]]==== (LIM domain kinases) | + | ====[[Kinase_Subfamily_LIMK|LIMK]]==== |
| + | (LIM domain kinases) | ||
| − | ====[[Kinase_Subfamily_TESK|TESK]]==== (Testis Expressed Serine Kinases) | + | ====[[Kinase_Subfamily_TESK|TESK]]==== |
| + | (Testis Expressed Serine Kinases) | ||
A separate subfamily, [[Kinase_Family_LISK-DD1|LISK-DD1]] has been reported only from Dictyostelium, and some fungi | A separate subfamily, [[Kinase_Family_LISK-DD1|LISK-DD1]] has been reported only from Dictyostelium, and some fungi | ||
Latest revision as of 08:10, 9 February 2022
Kinase Classification: Group TKL: Family LISK
The LISK family consists of two main subfamilies:
LIMK
(LIM domain kinases)
TESK
(Testis Expressed Serine Kinases)
A separate subfamily, LISK-DD1 has been reported only from Dictyostelium, and some fungi
Evolution
LISK-DD1 is seen in Dictyostelium and at least one fungus, while the other two are animal-specific.
Functions
Both TESK and LIMK subfamilies phosphorylate cofilin and inhibit its actin-capping function.
