Kinase Family STE11

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Kinase Classification: Group STE: Family STE11

STE11 (MAP3K, MEKK) kinases are part of the MAPK signaling cascades: they are activated by STE20 (MAP4K) and phosphorylate STE7 (MAP2K, MEK) kinases.

Major Subfamilies

MEKK1

MEKK2

MEKK4

MEKK15

ASK

CDC15


Evolution

STE11 kinases are found in almost all eukaryotes, with Plasmodium being a notable exception.

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