Kinase Family STE7
From WikiKinome
Kinase Classification: Group STE: Family STE7
STE7 (MAPKK, MAP2K, MEK) kinases are part of the MAPK signaling cascades: they are activated by STE11 (MAP3K, MAPKKK) and phosphorylate MAPK kinases. They are typically dual-specificity kinases, and phosphorylate a conserved TxY motif on MAPK.
Major Subfamilies
Evolution
STE11 kinases are found in almost all eukaryotes, with Plasmodium being a notable exception.
