HOME


Try NEW WEBSITE


TOOLS

KinBase
Blast
Logos
HyperTree
Sequences


KINOME PROJECTS

Human
Mouse
Sea Urchin
Drosophila
C. elegans
Sponge
Monosiga brevicollis
S. cerevisiae
Coprinopsis cinerea
Dictyostelium
Tetrahymena

Microbial Kinomes
Bacterial Spore Kinases

Kinase Evolution
Pseudokinases
WikiKinome


ABOUT

About Kinase.Com
What's New
Disclaimer
Help with viewers
Related Sites
Contact Us


The Mouse Kinome

These pages support our 2004 publication of the mouse kinome (the set of all mouse protein kinases) and its comparison to the human kinome:
The mouse kinome: Discovery and comparative genomics of all mouse protein kinases.
S Caenepeel, G Charydczak, S Sudarsanam, T Hunter and G Manning (2004).
PNAS 101 (32) 11707-11712.
PNAS have kindly allowed us to make the paper available to download as a PDF file. The paper is also available from the PNAS website.

All mouse sequences and classification are now available through our KinBase database, where dynamic alignments with human orthologs and other kinases can be carried out.

A related analysis of mouse kinases and phosphatases has been published by Forrest et al. We have looked at reasons for the differences between the two gene sets.

Supplemental Tables

Here are the supplemental tables to accompany the paper in Excel and tab-delimited formats
  • Legends to supplemental tables
  • Table 2: Kinase sequence, classification and annotation (Excel, Text)
  • Table 3: Coverage of kinase sequences in draft mouse genome (Excel, Text)
  • Table 4: Human-mouse kinase domain conservation, by family (Excel, Text)
  • Table 5: Species-specific indels in mouse-human kinase alignments (Excel, Text)
  • Table 6: Predictions of catalytically inactive mouse kinase domains (Excel, Text)
  • Table 7: Mouse kinase pseudogenes (Excel, Text)
  • Table 8: Mouse kinase mutations from MGI database (Excel, Text)
  • Tables 2-8 combined: (Excel)
Questions? See our feedback page.