RHOK_Hsap       FLDFRVLGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKKILMKVHSRF
GPRK7_Hsap      FTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLEKEILEKVSSPF
GPRK6_Hsap      FRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRF
GPRK5_Hsap      FRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEKVNSQF
GPRK4_Hsap      FRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILEKVQSRF
Gprk2_Dmel      FRMYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGESMVLIEKQILQKINSPF
GPRK6_Mmus      FRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRF
GPRK5_Mmus      FRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEKVNSQF
GPRK4_Mmus      FRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKRILEKLHSRF
F19C6.1_Cele    FRLYRVLGKGGFGEVCACQVRASGKMYALKKLEKKRVKKRHAETLSLNEKQILQRINSPF
RHOK_Mmus       FLDFRVLGKGGFGEVSACQMKATGKMYACKKLNKKRLKKRKGYQGAIVEKRILTKVHSRF
GPRK_Spur       ------------------------------------------------------------
AqueK008_Aque   FRQYRVLGKGGFGLVFACQSKFTGKMYALKKLEKKRVKKRKGEKLALNEKEVLEKVDSRF


RHOK_Hsap       IVSLAYAFETKADLCLVMTIMNGGDIRYHIYNVNEENPGFPEPRALFYTAQIICGLEHLH
GPRK7_Hsap      IVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVG--TRGLDMSRVIFYSAQIACGMLHLH
GPRK6_Hsap      VVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMG--QAGFPEARAVFYAAEICCGLEDLH
GPRK5_Hsap      VVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMG--NPGFEEERALFYAAEILCGLEDLH
GPRK4_Hsap      VVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLG--NPGFDEQRAVFYAAELCCGLEDLQ
Gprk2_Dmel      VVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMG-GEPGFELERARFYAAEVACGLQHLH
GPRK6_Mmus      VVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMG--QAGFPEARAVFYAAEICCGLEDLH
GPRK5_Mmus      VVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMG--NPGFEEERALFYAAEILCGLEDLH
GPRK4_Mmus      VVSLAYTYETKDALCLVLTIMNGGDLKYHIYNLG--DPGFEEPRAVFYAAELCCGLEDLQ
F19C6.1_Cele    VVSLAYAYETKDALCLVLTLMNGGDLKFHLYNLM--PGGFDEKRVQFYAAEITLGLQHLH
RHOK_Mmus       IVSLAYAFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIYYTAQIISGLEHLH
GPRK_Spur       ----------KEALCLVLTIMNGGDLKFHIHNMG--SPGFEEERARFYAAEILCGLEDLH
AqueK008_Aque   VVTLAYAYQSKDSLCMVLTLMNGGDLRFHIYSIG--SPGLEPERVVFYAAEIACGLHHLH
                          *  **:*:::*****:::*:: :     *:   *. :*:*::  *: .*:

RHOK_Hsap       QRRIVYRDLKPENVLLDNDGNVRISDLGLAVELLDGQSKTKGYAGTPGFMAPELLQ-GEE
GPRK7_Hsap      ELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKP-ITQRAGTNGYMAPEILMEKVS
GPRK6_Hsap      RERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQT-IKGRVGTVGYMAPEVVK-NER
GPRK5_Hsap      RENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDL-IRGRVGTVGYMAPEVLN-NQR
GPRK4_Hsap      RERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQR-VRGRVGTVGYMAPEVVN-NEK
Gprk2_Dmel      KQGIVYRDCKPENILLDDHGHVRISDLGLAVEIPEGEM-VRGRVGTVGYMAPEVID-NEK
GPRK6_Mmus      RERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQT-IKGRVGTVGYMAPEVVR-NER
GPRK5_Mmus      RENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDL-IRGRVGTVGYMAPEVLN-NQR
GPRK4_Mmus      RKRIVYRDLKPENILLDDHGHIRISDLGLAMEVPEGEM-VRGRVGTVGYMAPEIIN-HEK
F19C6.1_Cele    SERILYRDLKPENILLDDFGHVRISDLGLAVEIKDNEP-IKGRVGTVGYMAPEIVK-NER
RHOK_Mmus       QRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQNKTKGYAGTPGFMAPELLR-GEE
GPRK_Spur       RLRIVYRDMKPENILLDDHGHVRISDLGLAVEIPENDT-IRGRVGTVGYMAPEVVK-NER
AqueK008_Aque   TARIAYRDMKPDNILLDDAGHIRISDLGLAVHIPEGQS-VRGRVGTPGYMAPEVID-GHR
                     *** **:*:***: *: *:****** .:  ..      .** *:****::

RHOK_Hsap       YDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKHRIISEPVKY-PDKFSQASKDFC
GPRK7_Hsap      YSYPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNFTEEAKDIC
GPRK6_Hsap      YTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEY-SERFSPQARSLC
GPRK5_Hsap      YGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVY-SHKFSEEAKSIC
GPRK4_Hsap      YTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEY-SEKFSEDAKSIC
Gprk2_Dmel      YAFSPDWFSFGCLLYEMIEGQAPFRMRKEKVKREEVDRRVKEDPEKY-SSKFNDEAKSMC
GPRK6_Mmus      YTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVAEEY-TDRFSSQARSLC
GPRK5_Mmus      YGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVY-SSKFSEEAKSIC
GPRK4_Mmus      YTFSPDWWGLGCLIYEMIAGHSPFRKYKEKVNREELERRVKNETEEY-SERFSEDAKSIC
F19C6.1_Cele    YSYGVDWWGVGCLIYEMIEGKAPFRQRKEKVKREEVERRVREDQEKY-SEKFSEAARTLC
RHOK_Mmus       YDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRIISEPVKY-PEKFSQASKDFC
GPRK_Spur       YTFSPDYWGLGCLIYEMIEGRAPFRARKEKVKREEVDRRVKEDDEKY-SQKFSTEAQDIC
AqueK008_Aque   YTFAPDWWGMGCLIYEMICGRTPFRKHKERVSREDIERRIKDDRVCLDNSAFTEDSRSIC
                *    *::..*  :***: .: **:   :::. :::.:   .         *.  :: :*

RHOK_Hsap       EALLEKDPEKRLGFRD-----E--TCDKLRAHPLF
GPRK7_Hsap      RLFLAKKPEQRLGSRE-----K---SDDPRKHHFF
GPRK6_Hsap      SQLLCKDPAERLGCRG-----G--SAREVKEHPLF
GPRK5_Hsap      KMLLTKDAKQRLGCQE-----E--GAAEVKRHPFF
GPRK4_Hsap      RMLLTKNPSKRLGCRG-----E--GAAGVKQHPVF
Gprk2_Dmel      QQLLAKSIKQRLGCRN-----GRMGGQDVMAHPFF
GPRK6_Mmus      SQLLSKDPAERLGCRG-----G--GAREVKEHPLF
GPRK5_Mmus      NMLLTKDSKQRLGCQE-----E--GAAEVKRHPFF
GPRK4_Mmus      SMLLIKDPSKRLGCQR-----D--GVSAVKQHPIF
F19C6.1_Cele    RGLLHKEPGFRLGCRRVGRPED--GAEEIRAHPFF
RHOK_Mmus       EQLLEKDPEKRLGFRD-----G--TCDALRANVLF
GPRK_Spur       KKLLQKDPALRMGFEN-----G--TAQTVKDHSFF
AqueK008_Aque   DQFLDKVHATRLGCCG-----E--MFEDVKAHPFF
                  :* *    *:*                  : .*