Kinase Subfamily NEK8

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Kinase Classification: Group Other: Family NEK: Subfamily NEK8



Evolution

NEK8 is found in most holozoans (animals + choanoflagellates). It has a single copy in mammals (NEK8) and Drosophila (CG10951) but has duplicated in C. elegans (ZC581.1, Y39G10AR.4/nekl-2), sea urchin, sponge and elsewhere.


Domain Structure

Like NEK9, members have an N-terminal kinase domain followed by several RCC1 domains

Functions

References

  1. []
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